What is Lorihis?
Lorihis is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Lorihis is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.
Lorihis is also used to treat skin hives and itching in people with chronic skin reactions.
Lorihis may also be used for purposes not listed in this medication guide.
Treatment of seasonal allergic rhinitis, perennial rhinitis, urticaria, allergic dermatologic disorders, angioedema and conjunctivitis. Lorihis is generally considered to be ineffective in asthma.
Acute anaphylaxis should be treated with adrenaline; Lorihis and corticosteroids are given to prevent relapse.
Lorihis is also used to control the pruritus associated with skin disorders eg, atopic eczema.
How should I use Lorihis?
Use Lorihis orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Lorihis orally disintegrating tablets by mouth with or without food.
- Be sure that your hands are completely dry before you handle Lorihis orally disintegrating tablets. Use the tablet right away after you remove it from the tablet blister.
- To open the tablet blister, peel back the foil, then gently remove the tablet. Place the tablet on the tongue. The tablet will dissolve quickly. You may take Lorihis orally disintegrating tablets with or without water.
- If you miss a dose of Lorihis orally disintegrating tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Lorihis orally disintegrating tablets.
Uses of Lorihis in details
This medication is an antihistamine that treats symptoms such as itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergies. It is also used to relieve itching from hives.
Lorihis does not prevent hives or prevent/treat a serious allergic reaction (e.g., anaphylaxis). Therefore, if your doctor has prescribed epinephrine to treat allergic reactions, always carry your epinephrine injector with you. Do not use Lorihis in place of your epinephrine.
If you are self-treating with this medication, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.
Do not use this medication in children younger than 6 years unless directed by the doctor.
How to use Lorihis
If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. If your doctor has prescribed this medication, follow your doctor's directions and the instructions on your prescription label. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor or the product package, usually once or twice a day. Remove the tablet from its foil pack immediately before taking and place the tablet on the tongue. It will dissolve quickly. You may swallow the dissolved medication with or without water. Dosage is based on your age, condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age.
Tell your doctor if your allergy symptoms do not improve after 3 days of treatment or if your hives last more than 6 weeks. Seek immediate medical attention if your condition worsens or you think you have a serious medical problem (e.g., very serious allergic reaction/anaphylaxis).
Lorihis competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. Lorihis's anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease.
Use only with enclosed dosing cup
- adults and children 6 years and over: 2 teaspoonfuls (TSP) daily; do not take more than 2 teaspoonfuls (TSP) in 24 hours
- children 2 to under 6 years of age: 1 teaspoonful (TSP) daily; do not take more than 1 teaspoonful (TSP) in 24 hours
- children under 2 years of age: ask a doctor
- consumers with liver or kidney disease: ask a doctor
- each teaspoonful contains: sodium 5 mg
- do not use if tape imprinted with “SEALED FOR YOUR PROTECTION” on top and bottom flaps of carton is not intact.
- store between 20° and 25°C (68° and 77°F)
edetate disodium, flavor, glycerin, maltitol, monobasic sodium phosphate, phosphoric acid, propylene glycol, sodium benzoate, sorbitol, sucralose, purified water
Questions or comments ?
1-800-Lorihis (1-800-252-7484) or www.Lorihis.com
Distributed by Bayer HealthCare LLC, Whippany, NJ, USA, 07981. Revised: Dec 2015
Lorihis (10 mg once daily) has been coadministered with therapeutic doses of erythromycin, cimetidine, and ketoconazole in controlled clinical pharmacology studies in adult volunteers. Although increased plasma concentrations (AUC 0-24 hrs) of Lorihis and/or descarboethoxyloratadine were observed following coadministration of Lorihis with each of these drugs in normal volunteers (n = 24 in each study), there were no clinically relevant changes in the safety profile of Lorihis, as assessed by electrocardiographic parameters, clinical laboratory tests, vital signs, and adverse events. There were no significant effects on QTc intervals, and no reports of sedation or syncope. No effects on plasma concentrations of cimetidine or ketoconazole were observed. Plasma concentrations (AUC 0-24 hrs) of erythromycin decreased 15% with coadministration of Lorihis relative to that observed with erythromycin alone. The clinical relevance of this difference is unknown. These above findings are summarized in TABLE 1.
|TABLE 1 Effects on Plasma Concentrations (AUC 0-24 hrs) of Lorihis and Descarboethoxyloratadine After 10 Days of Coadministration (Lorihis 10 mg) in Normal Volunteers|
|Erythromycin (500 mg q8h)||+ 40%||+46%|
|Cimetidine (300 mg qid)||+103%||+ 6%|
|Ketoconazole (200 mg q12h)||+307%||+73%|
Lorihis side effects
Applies to Lorihis: oral fixed-combination tablets, oral orally disintegrating tablets, oral solution, oral tablets
Side effects include:
Children 2–5 years of age receiving oral solution: Diarrhea, epistaxis, pharyngitis, flu-like symptoms, fatigue, stomatitis, tooth disorder, earache, viral infection, rash.
Children 6–12 years of age receiving oral solution: Nervousness, wheezing, fatigue, hyperkinesia, abdominal pain, conjunctivitis, dysphonia, upper respiratory tract infection.
Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth.
Fixed combination Lorihis (the active ingredient contained in Lorihis Reditab) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.
You should not take this medication if you are allergic to Lorihis or to desloratadine (Clarinex).
Ask a doctor or pharmacist before taking this medicine if you have liver or kidney disease.
Do not give this medication to a child younger than 6 years old without the advice of a doctor.
Lorihis disintegrating tablets (Lorihis Reditab) may contain phenylalanine. Talk to your doctor before using this form of Lorihis if you have phenylketonuria (PKU).
Active ingredient matches for Lorihis:
Loratadine in Indonesia.
|Unit description / dosage (Manufacturer)||Price, USD|
|Lorihis 10 mg x 5 x 10's||$ 14.97|
|Lorihis 5 mg/5 mL x 60 mL x 1's||$ 2.62|
List of Lorihis substitutes (brand and generic names):
|Loridin Rapitabs (Latvia, Lithuania)|
|Lorin (Bangladesh, India)|
|10 mg x 10's (Stadmed)||$ 0.44|
|5 mg x 5 mL x 30ml (Stadmed)||$ 0.29|
|Lorin 10mg TAB / 10 (Stadmed)||$ 0.44|
|Lorin 5mg x 5mL SUSP / 30ml (Stadmed)||$ 0.29|
|LORIN SYRUP 1 bottle / 30 ML syrup each (Stadmed)||$ 0.44|
|LORIN TABLET 1 strip / 10 tablets each (Stadmed)||$ 0.63|
|LORIN tab 10 mg x 10's (Stadmed)||$ 0.44|
|LORIN oral susp 5 mg x 5 mL x 30ml (Stadmed)||$ 0.29|
|Lorin 5mg Syrup (Stadmed)||$ 0.44|
|Lorin 10mg Tablet (Stadmed)||$ 0.06|
|Lorinet 10 mg x 10 Blister x 10 Tablet|
|Lorinol (India, Myanmar)|
|Lorinol 10mg TAB / 10 (Micro Gratia)||$ 0.65|
|10 mg x 10's (Micro Gratia)||$ 0.65|
|LORINOL CREAM 1 tube / 15 GM cream each (Micro Gratia)||$ 2.41|
|LORINOL EYE DROP 1 packet / 5 ML eye drop each (Micro Gratia)||$ 1.51|
|LORINOL TABLET 1 strip / 10 tablets each (Micro Gratia)||$ 1.13|
|LORINOL tab 10 mg x 10's (Micro Gratia)||$ 0.65|
|Lorinol NA Cream (Micro Gratia)||$ 2.41|
|Lorinol NA Eye Drop (Micro Gratia)||$ 1.51|
|Lorinol 10mg Tablet (Micro Gratia)||$ 0.11|
|Lorinol-10 chewable tab 10 mg 10 x 10's (Micro Labs)|
|10 mg x 100's (Sidhbali)||$ 5.08|
|Lorispa 10mg TAB / 100 (Sidhbali)||$ 5.08|
|LORISPA tab 10 mg x 10's (Sidhbali)||$ 0.51|
|Lorispa 10mg TAB / 100 (Sidhbali)||$ 5.08|
|LORIT 10MG TABLET 1 strip / 10 tablets each (Wizad Biotech Pvt Ltd)||$ 0.63|
|Lorita 10 mg x 10 x 10's (Bangkok Lab & Cosmetic)|
|Lorita tab 10 mg 10 x 10's (Bangkok Lab & Cosmetic)|
|Loritin (Iceland, Malta, Taiwan)|
|Loritin 10 mg (Actavis)|
- DailyMed. "LORATADINE; PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "loratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "loratadine". http://www.drugbank.ca/drugs/DB00455 (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Lorihis are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Lorihis. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported usefulNo survey data has been collected yet
Consumer reported price estimatesNo survey data has been collected yet
Consumer reported time for resultsNo survey data has been collected yet
Consumer reported ageNo survey data has been collected yet
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Information checked by Dr. Sachin Kumar, MD Pharmacology