Mags Uses

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Mags indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.

For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.

Uses of Mags in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Mags is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.

Mags description

Each retard capsule contains Ambroxol hydrochloride 75 mg.

Each tablet contains Ambroxol hydrochloride 30 mg.

Each 5 mL of syrup contains Ambroxol hydrochloride 15 or 30 mg.

Each mL of syrup (infant drops) contains Ambroxol hydrochloride 6 mg.

Mags hydrochloride is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.

It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.

Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.

Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.

Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.

Mags dosage

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Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Mags).

Mags SR capsule is not suitable for children <12 years.

Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.

Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.

DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.

Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.

Mags interactions

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Amoxicillin may decrease the effectiveness of contraceptives for oral administration.

With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.

Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.

Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.

Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.

Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.

With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.

Mags side effects

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Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.

Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).

With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.

Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.

Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.

Mags contraindications

Hypersensitivity to Mags hydrochloride or to any other excipients of Mags.

In case of rare hereditary conditions that may be incompatible with an excipient of Mags, the use of Mags is contraindicated.



Active ingredient matches for Mags:

Ambroxol in India.

Ambroxol hydrochloride/guaiphenesin/menthol/terbutaline sulphate in India.


Unit description / dosage (Manufacturer)Price, USD
Mags Terbutaline sulphate 1.25 mg, Guaiphenesin 50 mg, Ambroxolhydrochloride 15 mg, Menthol2.5 mg. SYR / 100ml$ 0.51
100ml$ 0.51
MAGS syr 100ml (Plus India)$ 0.51

List of Mags substitutes (brand and generic names):

Max 30 mg x 50 x 10's (Pidek)
Max 30 mg x 1, 000's (Pidek)
500 mg x 10's (Pidek)$ 1.03
Max 30 mg x 500's (Pidek)
MAX cap 500 mg x 10's (Pidek)$ 1.03
Medibron 30 mg/5 mL x 60 mL (Medi-Rx)$ 2.44
Medibron 30 mg/5 mL x 120 mL (Medi-Rx)$ 3.81
Medibron 6 mg/1 mL x 15 mL (Medi-Rx)$ 2.03
Medibron oral drops 6 mg/mL 15 mL x 1's (Medi-Rx)$ 2.03
Medibron syr 30 mg/5 mL 60 mL x 1's (Medi-Rx)$ 2.44
Medibron syr 30 mg/5 mL 120 mL x 1's (Medi-Rx)$ 3.81
Medirox-A Roxithromycin 150 mg, Ambroxolhydrochloride 30 mg. TAB / 10$ 1.03
10's$ 1.03
Syrup; Oral; Ambroxol Hydrochloride 15 mg / 5 ml
Tablet; Oral; Ambroxol Hydrochloride 30 mg
Medox 7.5 mg x 1 Blister x 10 Tablet
Solution; Oral; Ambroxol (Ederka)
Misovan 30 mg x 500's (T. O. Chemicals)
Misovan 30 mg/5 mL x 60 mL (T. O. Chemicals)
Misovan 30 mg/5 mL x 3.8 L (T. O. Chemicals)
Misovan syr 30 mg/5 mL 60 mL x 1's (T. O. Chemicals)
Misovan syr 30 mg/5 mL 3800 mL x 1's (T. O. Chemicals)
Misovan tab 30 mg 500's (T. O. Chemicals)
Mokotam 30 mg x 1000's
Molapect 30 mg x 10 x 10's (Molex ayus)$ 5.46
Molapect 15 mg/5 mL x 60 mL x 1's (Molex ayus)$ 0.81
Molapect 30 mg/5 mL x 60 mL (Molex ayus)$ 1.09

References

  1. DailyMed. "TERBUTALINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "terbutaline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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