Mebeverinehydrochloride ERC Retard Uses

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Mebeverinehydrochloride ERC Retard indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.

Uses of Mebeverinehydrochloride ERC Retard in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Mebeverinehydrochloride ERC Retard is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.

Mebeverinehydrochloride ERC Retard description

Each capsule contains Mebeverine HCl 200 mg.

Mebeverinehydrochloride ERC Retard also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.

Mebeverinehydrochloride ERC Retard dosage

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Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).

Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.

Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.

Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).

It should not be chewed because the coating is intended to ensure a prolonged release mechanism.

Mebeverinehydrochloride ERC Retard interactions

No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Mebeverinehydrochloride ERC Retard and ethanol.

Incompatibilities: Not applicable.

Mebeverinehydrochloride ERC Retard side effects

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Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia and tachycardia have been reported in patients receiving Mebeverinehydrochloride ERC Retard.

Mebeverinehydrochloride ERC Retard contraindications

Hypersensitivity to Mebeverinehydrochloride ERC Retard HCl or to any of the excipients of Mebeverinehydrochloride ERC Retard.

Active ingredient matches for Mebeverinehydrochloride ERC Retard:

Mebeverine in Netherlands.


List of Mebeverinehydrochloride ERC Retard substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
MEBIZ CAPSULE SR 1 strip / 10 capsule srs each (Sun Pharma Laboratories Ltd)$ 2.37
Mebiz 200mg Capsule MR (Sun Pharmaceutical Industries Ltd)$ 0.26
Mebiz SR cap 200 mg 10's (Sun Pharma)
Mebrin 135mg TAB / 100 (Psycorem)$ 8.57
135 mg x 100's (Psycorem)$ 8.57
MEBRIN tab 135 mg x 10's (Psycorem)$ 0.86
Tablet; Oral; Mebeverine Hydrochloride 135 mg (Medipharm)
Tablet, Prolonged Release; Oral; Mebeverine Hydrochloride 200 mg
Menosor 135 mg x 3 x 10's (Tp)
10's (Zydus (Alidac))
200 mg x 10's (Zydus (Alidac))$ 1.45
Meva - SR-TAB / 10 (Zydus (Alidac))
Meva 200mg SR-CAP / 10 (Zydus (Alidac))$ 1.45
MEVA CAPSULE SR 1 strip / 10 capsule srs each (Zydus (Alidac))$ 2.07
MEVA SR cap 200 mg x 10's (Zydus (Alidac))$ 1.72
Meva 200mg Capsule SR (Zydus (Alidac))$ 0.23
MOREASE Capsule/ Tablet / 135mg / 10 units (Dr. Reddy's)$ 0.78
Morease 135mg TAB / 10 (Dr. Reddy's)$ 0.75
135 mg x 10's (Dr. Reddy's)$ 0.75
MOREASE 135 MG TABLET 1 strip / 10 tablets each (Dr. Reddy's)$ 1.17
MOREASE 200 MG CAPSULE SR 1 strip / 10 capsule srs each (Dr. Reddy's)$ 1.17
MOREASE tab 135 mg x 10's (Dr. Reddy's)$ 0.90
MOREASE SR cap 200 mg x 10's (Dr. Reddy's)$ 1.31
Morease 135mg TAB / 10 (Dr. Reddy's)$ 0.75
Morease 135mg Tablet (Dr. Reddy's)$ 0.12

References

  1. PubChem. "mebeverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Mebeverine". http://www.drugbank.ca/drugs/DB12554 (accessed September 17, 2018).
  3. MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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