Melodene-15 Overdose

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Overdose of Melodene-15 in details

When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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Symptoms: Overdosage in adults and children may include nausea, vomiting, breast tenderness, dizziness, abdominal pain, drowsiness/fatigue; withdrawal bleeding may occur in females.

Treatment: There is no specific antidote, and further treatment of overdose, if necessary, is directed to the symptoms.

Melodene-15 warnings

Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.

Use with caution in patients with impaired renal function and liver.

During the period of treatment required to conduct monitoring of blood glucose. Long-term therapy is necessary to periodically monitor the kidney function, liver and peripheral blood picture.

When using Melodene-15 it should be ensure adequate hydration of the body, the patient should be subjected to ultraviolet irradiation.

In experimental studies the mutagenic potential was not been identified. Long-term studies to determine the carcinogenicity of ofloxacin were not conducted.

Safety and efficacy in children and adolescents under the age of 18 is not defined.

Use with caution in patients whose activities are connected with the necessity of high concentration of attention and quickness of psychomotor reactions.

Melodene-15 precautions

Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Regular consultation with a physician is recommended while taking Melodene-15. The physician should be informed if the patient is suffering from the following conditions: Gallbladder disease, sickle-cell disease, conditions influenced by fluid retention, clinical depression, varicose veins, risk factor for cardiovascular disease eg, diabetes mellitus, smoking, obesity, hypertension and history of cardiovascular disease, undergoing laboratory tests ie, liver, thyroid, adrenal and renal function test, plasma concentrations of binding proteins and lipid/lipoprotein fractions, fibrinolysis and coagulation factors, inflammatory bowel disease.

Melodene-15 should not be used after the recent evacuation of a hydatidiform mole until urine and plasma gonadotropin concentrations have returned to normal.

References

  1. DrugBank. "GESTODENE". http://www.drugbank.ca/drugs/DB06730 (accessed September 17, 2018).
  2. MeSH. "Contraceptives, Oral, Synthetic". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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