What is Metoprolol 100 Stada/Metoprolol 200 Stada Retard?
Treating high blood pressure, alone or with other medicines; long-term treatment of chest pain; and reducing the risk of death because of heart problems in patients who have had a heart attack. It may also be used for other conditions as determined by your doctor.
Metoprolol 100 Stada/Metoprolol 200 Stada Retard is a beta-adrenergic blocking agent (beta-blocker). It works by reducing the amount of work the heart has to do (reduces chest pain) and the amount of blood the heart pumps out (lowers high blood pressure). It is also used to stabilize the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
Used alone or in combination with other antihypertensive agents for management of hypertension; long-term management of angina pectoris; MI (immediate-release tablets and injection); treatment of stable, symptomatic angina (New York Heart Association [NYHA] class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin ( Toprol XL only).
How should I use Metoprolol 100 Stada/Metoprolol 200 Stada Retard?
Use Metoprolol 100 Stada/Metoprolol 200 Stada Retard as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Metoprolol 100 Stada/Metoprolol 200 Stada Retard is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Metoprolol 100 Stada/Metoprolol 200 Stada Retard at home, a health care provider will teach you how to use it. Be sure you understand how to use Metoprolol 100 Stada/Metoprolol 200 Stada Retard. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
Do not use Metoprolol 100 Stada/Metoprolol 200 Stada Retard if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
If you miss a dose of Metoprolol 100 Stada/Metoprolol 200 Stada Retard, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Metoprolol 100 Stada/Metoprolol 200 Stada Retard.
Uses of Metoprolol 100 Stada/Metoprolol 200 Stada Retard in details
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Use: Labeled Indications
Angina: Long-term treatment of angina pectoris.
Heart failure with reduced ejection fraction (ER oral formulation): Treatment of stable, symptomatic (NYHA class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin to reduce the rate of mortality plus hospitalization in patients already receiving angiotensin-converting enzyme inhibitors, diuretics, and/or digoxin.
Hypertension: Management of hypertension. Note: Beta-blockers are not recommended as first-line therapy (ACC/AHA [Whelton 2017]).
Myocardial infarction: Treatment of hemodynamically stable acute myocardial infarction to reduce cardiovascular mortality (injection to be used in combination with Metoprolol 100 Stada/Metoprolol 200 Stada Retard oral maintenance therapy).
Off Label Uses
Based on the 2014 American Heart Association/American College of Cardiology/Heart Rhythm Society (AHA/ACC/HRS) guideline for the management of patients with atrial fibrillation (AF), the use of beta-blockers, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, for ventricular rate control in patients with paroxysmal, persistent, or permanent AF is effective and recommended.
Atrial fibrillation prevention after cardiac surgery
Based on the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guideline for coronary artery bypass graft surgery, beta-blockers are recommended to help prevent postoperative atrial fibrillation.
Based on the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guideline for the diagnosis and treatment of hypertrophic cardiomyopathy, a beta blocker (eg, Metoprolol 100 Stada/Metoprolol 200 Stada Retard) is an effective and recommended agent for the treatment of symptoms (eg, angina, dyspnea) in patients with obstructive or nonobstructive hypertrophic cardiomyopathy.
Marfan syndrome with aortic aneurysm
Based on the American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery (ACCF/AHA/AATS) guideline for the diagnosis and management of patients with thoracic aortic disease, a beta blocker (eg, Metoprolol 100 Stada/Metoprolol 200 Stada Retard) is an effective and recommended agent to reduce the rate of aortic dilatation in patients with Marfan syndrome and aortic aneurysm, unless a contraindication exists.
Data from small, randomized, active-controlled trials support the use of Metoprolol 100 Stada/Metoprolol 200 Stada Retard for prevention of migraines.
Based on evidence-based guidelines for pharmacologic treatment for episodic migraine prevention in adults from the American Academy of Neurology and the American Headache Society, Metoprolol 100 Stada/Metoprolol 200 Stada Retard is effective for migraine prevention in adults.
Based on the American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS) guidelines for the management of adult patients with supraventricular tachycardia, the use of an oral or intravenous beta-blocker, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, is effective and recommended for a variety of symptomatic supraventricular tachycardias (atrioventricular nodal reentrant tachycardia [AVNRT], atrioventricular reentrant tachycardia [AVRT], focal atrial tachycardia [AT], and multifocal atrial tachycardia [MAT]). In patients without pre-excitation, intravenous Metoprolol 100 Stada/Metoprolol 200 Stada Retard is recommended for acute treatment in hemodynamically stable patients and oral Metoprolol 100 Stada/Metoprolol 200 Stada Retard is recommended for ongoing management of symptomatic supraventricular tachycardias in patients who are not candidates for, or prefer not to undergo, catheter ablation.
Intravenous or oral Metoprolol 100 Stada/Metoprolol 200 Stada Retard may be useful for rate control in the acute treatment or ongoing management of hemodynamically stable patients with atrial flutter.
Based on the American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis, beta-blockers, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, are effective and recommended in the treatment of symptomatic thyrotoxicosis. Beta-blockers should also be considered in asymptomatic patients who are at increased risk of complications due to worsening hyperthyroidism.
Based on the American Heart Association/American College of Cardiology/Heart Rhythm Society (AHA/ACC/HRS) guideline for management of patients with ventricular arrhythmias and prevention of sudden cardiac death, beta-blockers are effective for control of ventricular arrhythmias and ventricular premature beats.
Parenteral administration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard shall be supervised by appropriate personnel, at sites where blood pressure and ECG measurements and resuscitation can be carried out.
Supraventricular Tachyarrhythmia: Initially, 5 mg (=5 mL) is to be given intravenously at 1-2 mg/minute. This dose can be repeated every 5 minute until the desired effect is reached. Usually a total dose of 10-15 mg (=10-15 mL) is sufficient. Recommended maximum intravenous dose: 20 mg (=20 mL).
Prophylaxis and Treatment of Myocardial Ischemia, Tachyarrhythmia and Pain if Suspected or Diagnosed Myocardial Infarction: Acute: Give 5 mg (=5 mL) intravenously. The dose can be repeated every 2 minutes, maximum dose 15 mg (=15 mL). 15 minutes after the last injection, give 50 mg Metoprolol 100 Stada/Metoprolol 200 Stada Retard orally every 6 hours for 48 hours. For continued (oral) treatment Betaloc tablets or Betaloc ZOK prolonged release tablets should be given.
Metoprolol 100 Stada/Metoprolol 200 Stada Retard is a CYP2D6-substrate. Drugs that inhibit CYP2D6 may have an effect on the plasma concentration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard. Examples of drugs that inhibit CYP2D6 are quinidine, terbinafine, paroxetine, fluoxetine, sertraline, celecoxib, propafenon and diphenhydramine. When treatment with these drugs are initiated the dose of Betaloc might have to be reduced for patients treated with Betaloc.
The following combinations with Metoprolol 100 Stada/Metoprolol 200 Stada Retard should be avoided: Barbituric acid derivatives, propafenone and verapamil.
The following combinations with Metoprolol 100 Stada/Metoprolol 200 Stada Retard may require a dose adjustment: Class I antiarrhythmic drugs, amiodarone, diphenhydramine, digitalis glycosides, diltiazem, epinephrine, phenylpropanolamine, nonsteroidal anti-inflammatory/antirheumatic drugs (NSAIDs), quinidine, clonidine and rifampicin.
Patients receiving concomitant treatment with other β-blockers (eg, eye drops) or MAO-inhibitors should be kept under close surveillance. In patients on β-receptor blocker therapy, inhalation anaesthetics enhance the cardiodepressant effect. The dosages of oral antidiabetics may have to be readjusted in patients taking β-blockers. The plasma concentration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard may increase when cimetidine or hydralazine are administered simultaneously.
Incompatibilities: Macrodex is not suitable for mixing with Metoprolol 100 Stada/Metoprolol 200 Stada Retard.
Compatibility: Betaloc solution for injection 1 mg/mL equivalent to up to Metoprolol 100 Stada/Metoprolol 200 Stada Retard 40 mg may be added to 1000 mL of the following solutions for infusion: Sodium chloride 0.9%, mannitol 150 mg/mL, glucose 100 mg/mL, glucose 50 mg/mL, fructose 200 mg/mL, invertose 100 mg/mL, Ringer, Ringer glucose, Ringer acetate.
Metoprolol 100 Stada/Metoprolol 200 Stada Retard side effects
In addition to its needed effects, some unwanted effects may be caused by Metoprolol 100 Stada/Metoprolol 200 Stada Retard (the active ingredient contained in Metoprolol 100 Stada/Metoprolol 200 Stada Retard). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard:
chest pain or discomfort
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
shortness of breath
slow or irregular heartbeat
unusual tiredness or weakness
Bloating or swelling of the face, arms, hands, lower legs, or feet
decreased urine output
difficult or labored breathing
difficulty with speaking
dilated neck veins
disturbed color perception
fast, pounding, or racing heartbeat or pulse
halos around lights
inability to move the arms, legs, or facial muscles
inability to speak
loss of vision
overbright appearance of lights
pain, tension, and weakness upon walking that subsides during periods of rest
paleness or cold feeling in the fingertips and toes
rapid weight gain
seeing, hearing, or feeling things that are not there
short-term memory loss
swelling of the face, fingers, feet, or lower legs
tightness in the chest
tingling of the hands or feet
tingling or pain in the fingers or toes when exposed to cold
unusual weight gain or loss
Bluish color skin of the fingers or toes
continuing loss of appetite
continuing or severe abdominal or stomach pain
continuing or severe nausea and vomiting
difficulty with moving
general tiredness and weakness
increased frequency of urination
lower back or side pain
muscle pain or stiffness
numbness of the fingers or toes
pain, swelling, or redness in the joints
sores, ulcers, or white spots on the lips or in the mouth
unpleasant breath odor
unusual bleeding or bruising
upper right abdominal or stomach pain
vomiting of blood
yellow eyes and skin
Incidence not known:
Black, tarry stools
blood in the urine or stools
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
cool, sweaty skin
pinpoint red spots on the skin
If any of the following symptoms of overdose occur while taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard, get emergency help immediately:
Symptoms of overdose:
Bluish color of the fingernails, lips, skin, palms, or nail beds
change in consciousness
loss of consciousness
no blood pressure or pulse
stopping of heart
very drowsy or sleepy
Minor Side Effects
Some of the side effects that can occur with Metoprolol 100 Stada/Metoprolol 200 Stada Retard may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
decreased interest in sexual intercourse
difficulty having a bowel movement (stool)
excess air or gas in stomach or intestines
feeling of constant movement of self or surroundings
feeling of indigestion
feeling sad or empty
inability to have or keep an erection
loss in sexual ability, desire, drive, or performance
loss of interest or pleasure
pain in the chest below the breastbone
redness or other discoloration of the skin
sensation of spinning
continuing ringing or buzzing or other unexplained noise in the ears
hair loss or thinning of the hair
increased sensitivity of the skin to sunlight
pain of penis on erection
Incidence not known:
Change in taste or bad, unusual, or unpleasant (after) taste
Known hypersensitivity to Metoprolol 100 Stada/Metoprolol 200 Stada Retard or other β-blockers. Cardiogenic shock. Sick sinus syndrome. AV block. Patients with unstable, uncompensated heart failure (pulmonary oedema, hypoperfusion or hypotension), and patients with continuous or intermittent inotropic therapy acting through β-receptor agonism. Symptomatic bradycardia or hypotension. Metoprolol 100 Stada/Metoprolol 200 Stada Retard should not be given to patients with suspected acute myocardial infarction as long as the heart rate is <45 beats/min, the P-Q interval is >0.24 sec or the systolic blood pressure is <100 mmHg. In treatment of supraventricular tachyarrhythmia, Metoprolol 100 Stada/Metoprolol 200 Stada Retard should not be given IV to patients with a systolic blood pressure <110 mmHg. Serious peripheral vascular disease with gangrene threat.
Active ingredient matches for Metoprolol 100 Stada/Metoprolol 200 Stada Retard:
DailyMed. "METOPROLOL FUMARATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Metoprolol 100 Stada/Metoprolol 200 Stada Retard are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
Consumer reported useful
No survey data has been collected yet
Consumer reported price estimates
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1 consumer reported time for results
To what extent do I have to use Metoprolol 100 Stada/Metoprolol 200 Stada Retard before I begin to see changes in my health conditions? As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions. Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard. To get the time effectiveness of using Metoprolol 100 Stada/Metoprolol 200 Stada Retard drug by other patients, please click here.
2 consumers reported age
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