Metoprolol 100 Stada/Metoprolol 200 Stada Retard Uses

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What is Metoprolol 100 Stada/Metoprolol 200 Stada Retard?

Treating high blood pressure, alone or with other medicines; long-term treatment of chest pain; and reducing the risk of death because of heart problems in patients who have had a heart attack. It may also be used for other conditions as determined by your doctor.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard is a beta-adrenergic blocking agent (beta-blocker). It works by reducing the amount of work the heart has to do (reduces chest pain) and the amount of blood the heart pumps out (lowers high blood pressure). It is also used to stabilize the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Used alone or in combination with other antihypertensive agents for management of hypertension; long-term management of angina pectoris; MI (immediate-release tablets and injection); treatment of stable, symptomatic angina (New York Heart Association [NYHA] class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin ( Toprol XL only).

How should I use Metoprolol 100 Stada/Metoprolol 200 Stada Retard?

Use Metoprolol 100 Stada/Metoprolol 200 Stada Retard as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Metoprolol 100 Stada/Metoprolol 200 Stada Retard.

Uses of Metoprolol 100 Stada/Metoprolol 200 Stada Retard in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Use: Labeled Indications

Angina: Long-term treatment of angina pectoris.

Heart failure with reduced ejection fraction (ER oral formulation): Treatment of stable, symptomatic (NYHA class II or III) heart failure of ischemic, hypertensive, or cardiomyopathic origin to reduce the rate of mortality plus hospitalization in patients already receiving angiotensin-converting enzyme inhibitors, diuretics, and/or digoxin.

Hypertension: Management of hypertension. Note: Beta-blockers are not recommended as first-line therapy (ACC/AHA [Whelton 2017]).

Myocardial infarction: Treatment of hemodynamically stable acute myocardial infarction to reduce cardiovascular mortality (injection to be used in combination with Metoprolol 100 Stada/Metoprolol 200 Stada Retard oral maintenance therapy).

Off Label Uses

Atrial fibrillation/flutter

Based on the 2014 American Heart Association/American College of Cardiology/Heart Rhythm Society (AHA/ACC/HRS) guideline for the management of patients with atrial fibrillation (AF), the use of beta-blockers, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, for ventricular rate control in patients with paroxysmal, persistent, or permanent AF is effective and recommended.

Atrial fibrillation prevention after cardiac surgery

Based on the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guideline for coronary artery bypass graft surgery, beta-blockers are recommended to help prevent postoperative atrial fibrillation.

Hypertrophic cardiomyopathy

Based on the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) guideline for the diagnosis and treatment of hypertrophic cardiomyopathy, a beta blocker (eg, Metoprolol 100 Stada/Metoprolol 200 Stada Retard) is an effective and recommended agent for the treatment of symptoms (eg, angina, dyspnea) in patients with obstructive or nonobstructive hypertrophic cardiomyopathy.

Marfan syndrome with aortic aneurysm

Based on the American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery (ACCF/AHA/AATS) guideline for the diagnosis and management of patients with thoracic aortic disease, a beta blocker (eg, Metoprolol 100 Stada/Metoprolol 200 Stada Retard) is an effective and recommended agent to reduce the rate of aortic dilatation in patients with Marfan syndrome and aortic aneurysm, unless a contraindication exists.

Migraine prophylaxis

Data from small, randomized, active-controlled trials support the use of Metoprolol 100 Stada/Metoprolol 200 Stada Retard for prevention of migraines.

Based on evidence-based guidelines for pharmacologic treatment for episodic migraine prevention in adults from the American Academy of Neurology and the American Headache Society, Metoprolol 100 Stada/Metoprolol 200 Stada Retard is effective for migraine prevention in adults.

Supraventricular tachycardia (eg, atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, focal atrial tachycardia)

Based on the American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS) guidelines for the management of adult patients with supraventricular tachycardia, the use of an oral or intravenous beta-blocker, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, is effective and recommended for a variety of symptomatic supraventricular tachycardias (atrioventricular nodal reentrant tachycardia [AVNRT], atrioventricular reentrant tachycardia [AVRT], focal atrial tachycardia [AT], and multifocal atrial tachycardia [MAT]). In patients without pre-excitation, intravenous Metoprolol 100 Stada/Metoprolol 200 Stada Retard is recommended for acute treatment in hemodynamically stable patients and oral Metoprolol 100 Stada/Metoprolol 200 Stada Retard is recommended for ongoing management of symptomatic supraventricular tachycardias in patients who are not candidates for, or prefer not to undergo, catheter ablation.

Intravenous or oral Metoprolol 100 Stada/Metoprolol 200 Stada Retard may be useful for rate control in the acute treatment or ongoing management of hemodynamically stable patients with atrial flutter.

Thyrotoxicosis

Based on the American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis, beta-blockers, including Metoprolol 100 Stada/Metoprolol 200 Stada Retard, are effective and recommended in the treatment of symptomatic thyrotoxicosis. Beta-blockers should also be considered in asymptomatic patients who are at increased risk of complications due to worsening hyperthyroidism.

Ventricular arrhythmias

Based on the American Heart Association/American College of Cardiology/Heart Rhythm Society (AHA/ACC/HRS) guideline for management of patients with ventricular arrhythmias and prevention of sudden cardiac death, beta-blockers are effective for control of ventricular arrhythmias and ventricular premature beats.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard description

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Each mL of solution for injection also contains sodium chloride 9 mg and water for injection.

Betaloc solution for injection 1 mg/mL has a pH of approximately 6. Clear colourless solution.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard dosage

Parenteral administration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard shall be supervised by appropriate personnel, at sites where blood pressure and ECG measurements and resuscitation can be carried out.

Supraventricular Tachyarrhythmia: Initially, 5 mg (=5 mL) is to be given intravenously at 1-2 mg/minute. This dose can be repeated every 5 minute until the desired effect is reached. Usually a total dose of 10-15 mg (=10-15 mL) is sufficient. Recommended maximum intravenous dose: 20 mg (=20 mL).

Prophylaxis and Treatment of Myocardial Ischemia, Tachyarrhythmia and Pain if Suspected or Diagnosed Myocardial Infarction: Acute: Give 5 mg (=5 mL) intravenously. The dose can be repeated every 2 minutes, maximum dose 15 mg (=15 mL). 15 minutes after the last injection, give 50 mg Metoprolol 100 Stada/Metoprolol 200 Stada Retard orally every 6 hours for 48 hours. For continued (oral) treatment Betaloc tablets or Betaloc ZOK prolonged release tablets should be given.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard interactions

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What other drugs will affect Metoprolol 100 Stada/Metoprolol 200 Stada Retard?

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Metoprolol 100 Stada/Metoprolol 200 Stada Retard is a CYP2D6-substrate. Drugs that inhibit CYP2D6 may have an effect on the plasma concentration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard. Examples of drugs that inhibit CYP2D6 are quinidine, terbinafine, paroxetine, fluoxetine, sertraline, celecoxib, propafenon and diphenhydramine. When treatment with these drugs are initiated the dose of Betaloc might have to be reduced for patients treated with Betaloc.

The following combinations with Metoprolol 100 Stada/Metoprolol 200 Stada Retard should be avoided: Barbituric acid derivatives, propafenone and verapamil.

The following combinations with Metoprolol 100 Stada/Metoprolol 200 Stada Retard may require a dose adjustment: Class I antiarrhythmic drugs, amiodarone, diphenhydramine, digitalis glycosides, diltiazem, epinephrine, phenylpropanolamine, nonsteroidal anti-inflammatory/antirheumatic drugs (NSAIDs), quinidine, clonidine and rifampicin.

Patients receiving concomitant treatment with other β-blockers (eg, eye drops) or MAO-inhibitors should be kept under close surveillance. In patients on β-receptor blocker therapy, inhalation anaesthetics enhance the cardiodepressant effect. The dosages of oral antidiabetics may have to be readjusted in patients taking β-blockers. The plasma concentration of Metoprolol 100 Stada/Metoprolol 200 Stada Retard may increase when cimetidine or hydralazine are administered simultaneously.

Incompatibilities: Macrodex is not suitable for mixing with Metoprolol 100 Stada/Metoprolol 200 Stada Retard.

Compatibility: Betaloc solution for injection 1 mg/mL equivalent to up to Metoprolol 100 Stada/Metoprolol 200 Stada Retard 40 mg may be added to 1000 mL of the following solutions for infusion: Sodium chloride 0.9%, mannitol 150 mg/mL, glucose 100 mg/mL, glucose 50 mg/mL, fructose 200 mg/mL, invertose 100 mg/mL, Ringer, Ringer glucose, Ringer acetate.

Metoprolol 100 Stada/Metoprolol 200 Stada Retard side effects

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What are the possible side effects of Metoprolol 100 Stada/Metoprolol 200 Stada Retard?

Applies to Metoprolol 100 Stada/Metoprolol 200 Stada Retard: oral tablet, oral tablet extended release

Other dosage forms:

In addition to its needed effects, some unwanted effects may be caused by Metoprolol 100 Stada/Metoprolol 200 Stada Retard (the active ingredient contained in Metoprolol 100 Stada/Metoprolol 200 Stada Retard). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard:

More common:

Less common: Rare Incidence not known:

If any of the following symptoms of overdose occur while taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard, get emergency help immediately:

Symptoms of overdose:

Minor Side Effects

Some of the side effects that can occur with Metoprolol 100 Stada/Metoprolol 200 Stada Retard may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Rare Incidence not known:

Metoprolol 100 Stada/Metoprolol 200 Stada Retard contraindications

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What is the most important information I should know about Metoprolol 100 Stada/Metoprolol 200 Stada Retard?

Known hypersensitivity to Metoprolol 100 Stada/Metoprolol 200 Stada Retard or other β-blockers. Cardiogenic shock. Sick sinus syndrome. AV block. Patients with unstable, uncompensated heart failure (pulmonary oedema, hypoperfusion or hypotension), and patients with continuous or intermittent inotropic therapy acting through β-receptor agonism. Symptomatic bradycardia or hypotension. Metoprolol 100 Stada/Metoprolol 200 Stada Retard should not be given to patients with suspected acute myocardial infarction as long as the heart rate is <45 beats/min, the P-Q interval is >0.24 sec or the systolic blood pressure is <100 mmHg. In treatment of supraventricular tachyarrhythmia, Metoprolol 100 Stada/Metoprolol 200 Stada Retard should not be given IV to patients with a systolic blood pressure <110 mmHg. Serious peripheral vascular disease with gangrene threat.

Active ingredient matches for Metoprolol 100 Stada/Metoprolol 200 Stada Retard:

Metoprolol tartrate in Thailand.


Unit description / dosage (Manufacturer)Price, USD
Metoprolol 100 Stada tab 100 mg 100's (Stada)
Metoprolol 200 Stada Retard tab 200 mg 100's (Stada)
Metoprolol 200 Stada Retard retard tab 200 mg 100's (Stada)

List of Metoprolol 100 Stada/Metoprolol 200 Stada Retard substitutes (brand and generic names):

Metoprolol TV Pharm 50 mg x 5 Blister x 10 Tablet
25 mg x 10's (Zinnia)$ 0.42
50 mg x 10's (Zinnia)$ 0.68
Metosafe-XL 25mg TAB / 10 (Zinnia)$ 0.42
Metosafe-XL 50mg TAB / 10 (Zinnia)$ 0.68
METOSAFE-XL tab 25 mg x 10's (Zinnia)$ 0.42
METOSAFE-XL tab 50 mg x 10's (Zinnia)$ 0.68
Metosafe-XL 25mg TAB / 10 (Zinnia)$ 0.42
Metosafe-XL 50mg TAB / 10 (Zinnia)$ 0.68
Metospec 50 mg x 100's (Pharmaspec)$ 9.25
Metospec 100 mg x 100's (Pharmaspec)$ 12.22
METOZAAR-XL film-coated tab 12.5 mg x 10's (Corona (Wellness))$ 0.27
METOZAAR-XL film-coated tab 25 mg x 15's (Corona (Wellness))$ 0.63
METOZAAR-XL film-coated tab 50 mg x 10's (Corona (Wellness))$ 0.48
Montebloc 50 mg x 100's (Danlex)$ 7.78
Montebloc 100 mg x 100's (Danlex)$ 12.22
25 mg x 100's
50 mg x 100's
MT-Loc 25mg TAB / 100
MT-Loc 50mg TAB / 100
MT-Loc 25mg TAB / 100
MT-Loc 50mg TAB / 100
REVELOL-XL ER tab 25 mg x 10's (IPCA)$ 0.72
REVELOL-XL ER tab 50 mg x 10's (IPCA)$ 0.99
REVELOL-XL ER tab 100 mg x 10's (IPCA)$ 1.33
25 mg x 10's (Lupin (CVN))$ 0.69
Starpress-XL 25mg ER-FC-TAB / 10 (Lupin (CVN))$ 0.69
Starpress-XL 50mg ER-FC-TAB / 10 (Lupin (CVN))$ 1.15
STARPRESS-XL 100 MG TABLET 1 strip / 10 tablets each (Lupin (CVN))$ 1.35
STARPRESS-XL 12.5 MG TABLET 1 strip / 10 tablets each (Lupin (CVN))$ 0.44
STARPRESS-XL 25 MG TABLET 1 strip / 15 tablets each (Lupin (CVN))$ 0.94
STARPRESS-XL 50 MG TABLET 1 strip / 15 tablets each (Lupin (CVN))$ 1.33
STARPRESS-XL ER tab 12.5 mg x 10's (Lupin (CVN))$ 0.44
STARPRESS-XL ER tab 25 mg x 15's (Lupin (CVN))$ 0.94
STARPRESS-XL ER tab 50 mg x 15's (Lupin (CVN))$ 1.33
STARPRESS-XL ER tab 100 mg x 10's (Lupin (CVN))$ 1.35
Starpress-XL 25mg ER-FC-TAB / 10 (Lupin (CVN))$ 0.69
Starpress-XL 50mg ER-FC-TAB / 10 (Lupin (CVN))$ 1.15

References

  1. DailyMed. "METOPROLOL FUMARATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "metoprolol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "metoprolol". http://www.drugbank.ca/drugs/DB00264 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Metoprolol 100 Stada/Metoprolol 200 Stada Retard are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

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1 consumer reported time for results

To what extent do I have to use Metoprolol 100 Stada/Metoprolol 200 Stada Retard before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Metoprolol 100 Stada/Metoprolol 200 Stada Retard. To get the time effectiveness of using Metoprolol 100 Stada/Metoprolol 200 Stada Retard drug by other patients, please click here.
Users%
2 weeks1
100.0%


2 consumers reported age

Users%
> 602
100.0%


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