The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Miconazole Dosage
Applies to the following strength(s): 50 mg; 10 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Oral Thrush
Usual Pediatric Dose for:
Oral Thrush
Additional dosage information:
Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments
Usual Adult Dose for
Oral Thrush
Oropharyngeal candidiasis: Apply 50 mg buccally to the upper gum region once a day for 14 consecutive days.
Usual Pediatric Dose for
Oral Thrush
Oropharyngeal candidiasis:
16 years or older: Apply 50 mg buccally to the upper gum region once a day for 14 consecutive days.
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
The manufacturer recommends caution when administering this drug to patients with liver dysfunction.
Precautions
Miconazole buccal tablets are contraindicated in patients with known hypersensitivity (e.g., anaphylaxis) to milk protein concentrate.
Allergic reactions (including anaphylactic reactions and hypersensitivity) have been reported with the use of Miconazole products. Miconazole should be discontinued at once at the first sign of hypersensitivity.
There are no data regarding cross-hypersensitivity between Miconazole and other azole antifungal agents. Patients with a history of hypersensitivity to azoles should be monitored.
Safety and effectiveness have not been established in pediatric patients less than 16 years of age.
Dialysis
No adjustment recommended.
Other Comments
Miconazole buccal tablets should be applied with dry hands each morning after brushing teeth. The tablets should be placed against the upper gum, above the incisor tooth, and held in place with slight pressure over the upper lip for 30 seconds to ensure adhesion. Once in place, the buccal tablet stays in position and gradually dissolves. Subsequent applications should be made to alternate sides of the mouth. Any remaining tablet material should be cleared away before the next tablet is applied.
Miconazole buccal tablets should not be crushed, chewed, or swallowed. Food and drink can be taken normally when the buccal tablet is in place but chewing gum should be avoided.
If the Miconazole buccal tablet does not adhere or falls off within the first 6 hours, the same tablet should be repositioned at once; however, if the tablet still does not adhere, a new tablet should be used. If the buccal tablet is swallowed within the first 6 hours, the patient should drink a glass of water and a new tablet should be applied only once. If the buccal tablet falls off or is swallowed after it was in place for at least 6 hours, a new tablet should not be applied until the next scheduled dose.
More about Miconazole
Side Effects
During Pregnancy or Breastfeeding
Dosage Information
Drug Interactions
Support Group
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Consumer resources
Miconazole
Miconazole oral buccal
Miconazole Buccal mucosa (Advanced Reading)
Other brands: Oravig
Professional resources
Miconazole (Oral) (Wolters Kluwer)
Related treatment guides
Oral Thrush
What other drugs will affect Miconazole?
It is not likely that other drugs you take orally or inject will have an effect on topically applied Miconazole. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
Miconazole interactions
Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Miconazole, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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Interaction with other medicinal products and other forms of interaction: When using any concomitant medication, the corresponding label should be consulted for information on the route of metabolism. Miconazole can inhibit the metabolism of drugs metabolized by the CYP3A4 and CYP2C9 enzyme systems. This can result in an increase and/or prolongation of their effects, including adverse effects.
Drugs which should not be used during treatment with Miconazole:
Oral Miconazole is contraindicated with the co-administration of the following drugs that are subject to metabolism by CYP3A4 : Substrates known to prolong QT-interval eg, astemizole, bepridil, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole and terfenadine; ergot alkaloids; HMG-CoA reductase inhibitors eg, simvastatin and lovastatin; triazolam and oral midazolam.
When co-administered with oral Miconazole, the following drugs should be used with caution because of a possible increase or prolongation of the therapeutic outcome and/or adverse effects. If necessary, their dosage should be reduced and when appropriate, plasma levels monitored: Others:
Oral hypoglycemics (CYP2C9), phenytoin (CYP2C9), carbamazepine, buspirone, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine.
Other drugs subject to metabolism by CYP3A4: HIV protease inhibitors eg, saquinavir; certain antineoplastic agents eg, vinca alkaloids, busulfan and docetaxel; certain calcium channel blockers eg, dihydropyridines and verapamil; certain immunosuppressive agents: cyclosporine, tacrolimus, sirolimus (rapamycin); others: alfentanil, alprazolam, brotizolam, buspirone, carbamazepine, cilostasol, disopyramide, ebastin, methylprednisolone, midazolam IV, reboxetine, rifabutin, sildenafil and trimetrexate.
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References
DailyMed. "MICONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
European Chemicals Agency - ECHA. "Miconazole: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Miconazole are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Miconazole. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
1 consumer reported frequency of use
How frequently do I need to take Miconazole? It was reported by ndrugs.com website users that Miconazole should ideally be taken Once in a day as the most common frequency of the Miconazole. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Miconazole should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
Users
%
Once in a day
1
100.0%
2 consumers reported doses
What doses of Miconazole drug you have used? The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Miconazole drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users
%
501mg-1g
1
50.0%
11-50mg
1
50.0%
Consumer reviews
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