Moxiflox Uses

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What is Moxiflox?

Moxiflox ophthalmic (eye) solution is used to treat infections of the eye, such as bacterial conjunctivitis. Moxiflox belongs to a group of medicines called fluoroquinolone antibiotics. It works by killing bacteria that cause conjunctivitis.

Moxiflox is available only with your doctor's prescription.

Moxiflox indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Moxiflox Tablets and I.V. are indicated for the treatment of adults ( ≥ 18 years of age) with infections caused by susceptible strains of the designated microorganisms in the conditions listed below. Acute Bacterial Sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.

Acute Bacterial Exacerbation of Chronic Bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, methicillin-susceptible Staphylococcus aureus, or Moraxella catarrhalis.

Community Acquired Pneumonia caused by Streptococcus pneumoniae (including multi-drug resistant strains*), Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus, Klebsiella pneumoniae, Mycoplasma pneumoniae, or Chlamydia pneumoniae.

* MDRSP, Multi-drug resistant Streptococcus pneumoniae includes isolates previously known as PRSP (Penicillin-resistant S. pneumoniae), and are strains resistant to two or more of the following antibiotics: penicillin (MIC ≥ 2 μg/mL), 2nd generation cephalosporins (e.g., cefuroxime), macrolides, tetracyclines, and trimethoprim/sulfamethoxazole.

Uncomplicated Skin and Skin Structure Infections caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.

Complicated Intra-Abdominal Infections including polymicrobial infections such as abscess caused by Escherichia coli, Bacteroides fragilis, Streptococcus anginosus, Streptococcus constellatus, Enterococcus faecalis, Proteus mirabilis, Clostridium perfringens, Bacteroides thetaiotaomicron, or Peptostreptococcus species.

Complicated Skin and Skin Structure Infections caused by methicillin-susceptible Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, or Enterobacter cloacae.

Appropriate culture and susceptibility tests should be performed before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to Moxiflox. Therapy with Moxiflox may be initiated before results of these tests are known; once results become available, appropriate therapy should be continued.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Moxiflox and other antibacterial drugs, Moxiflox should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Moxiflox?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

If you wear contact lenses, remove them before applying Moxiflox ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

  • Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.

  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Moxiflox ophthalmic is most often used for 7 days in a row. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store at cool room temperature, away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

Uses of Moxiflox in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Moxiflox is used to treat bacterial infections of the respiratory tract, infections of female upper genital tract, abdominal infections and infections of skin and eye.

Moxiflox description

infoPharmacology is a crucial part of medicine wherein various medications are used to advance the well-being of an individual. Some drugs cure the infection or a disease; few prevent the occurrence of a symptom or a disease, and few are used in long-term treatment of the disease. Drugs are obtained from the plants as well as they can be synthesized organically. The drugs are used in various combinations or a single drug by the pharmaceutical industry during its preparation. The half-life of each medicine is different, and the dosage of the drug depends on the half-life of the drug.

Each tablet contains Moxiflox HCl 436.8 mg equivalent to Moxiflox 400 mg. It also contains croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, hypromellose, macrogol 4000, titanium dioxide (E171) and ferric oxide (E172) as inactive constituents.

Each 250 mL solution for infusion contain Moxiflox HCl 436.8 mg equivalent to Moxiflox 400 mg. It also contains sodium chloride, 1N hydrochloric acid, 2N sodium hydroxide and water for injection. The solution for infusion (250 mL) contains sodium 34 mmol.

Active ingredient matches for Moxiflox:

Moxifloxacin in Egypt, Philippines.

Moxifloxacin HCl in Philippines.


Unit description / dosage (Manufacturer)Price, USD
Moxiflox 400 mg x 24's$ 87.89
MOXIFLOX 400 MG TABLET 1 strip / 5 tablets each (Cipla Ltd)$ 1.96
MOXIFLOX EYE DROP 1 packet / 5 ML eye drop each (Cipla Ltd)$ 1.39
Moxiflox FC tab 400 mg 24's (InnoGen Pharmaceuticals)$ 3.11
MOXIFLOX film-coated tab 400 mg x 5's (Cipla)$ 1.98
Moxiflox 400mg Tablet (Cipla Ltd)$ 0.39
Moxiflox NA Eye Drop (Cipla Ltd)$ 1.39

List of Moxiflox substitutes (brand and generic names):

Tablet; Oral; Moxifloxacin Hydrochloride 400 mg
Solution; Ophthalmic; Moxifloxacin Hydrochloride 0.5%
Vigamox 0.5% Solution 3ml Bottle$ 90.72
Vigamox 0.5% eye drops$ 27.22
Avelox 400 mg tablet$ 16.68
Avelox abc pack 400 mg tablet$ 16.35
Avelox iv 400 mg/250 ml$ 0.17
Tablets; Oral; Moxifloxacin Hydrochloride 400 mg
MOXIFLOXACIN 400MG TABLET 1 strip / 5 tablets each (Jan Aushadhi)$ 1.46
Moxifloxacin injection, solution 400 mg/250mL (Fresenius Kabi USA, LLC (US))
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Moxifloxacin tablet, film coated 400 mg/1 (Major Pharmaceuticals (US))

References

  1. Wikipedia. "moxifloxacin: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Moxifloxac... (accessed September 18, 2017).
  2. PubChem. "moxifloxacin". https://pubchem.ncbi.nlm.nih.gov/compoun... (accessed September 18, 2017).
  3. FDA Orange Book. "Patent:9114168: The publication, Approved Drug Products with Therapeutic Equivalence Evaluations (the List, commonly known as the Orange Book), identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act (the Act).". https://www.fda.gov/Drugs/InformationOnD... (accessed September 18, 2017).

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