What are the possible side effects of Moxifloxacin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives, or the first sign of a skin rash; difficult breathing; swelling of your face, lips, tongue, or throat.
Moxifloxacin may cause swelling or tearing of (rupture) a tendon, especially in your ankle. Moxifloxacin can also have serious effects on your nerves, and may cause permanent nerve damage. Stop taking this medicine and call your doctor at once if you have:
signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions); or
nerve symptoms--numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position.
Stop using moxifloxacin and call your doctor at once if you have:
headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
muscle weakness or trouble breathing;
diarrhea that is watery or bloody;
the first sign of any skin rash, no matter how mild;
sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, easy bruising or bleeding, pale or yellowed skin;
depression, confusion, hallucinations, paranoia, tremors, feeling restless or anxious, insomnia, nightmares, thoughts about suicide or hurting yourself;
high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss;
low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or
increased pressure inside the skull-- severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Moxifloxacin in details
Applies to moxifloxacin ophthalmic: ophthalmic solution
As well as its needed effects, moxifloxacin ophthalmic (the active ingredient contained in Moxifloxacin) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking moxifloxacin ophthalmic, check with your doctor immediately:
Incidence not known:
- Fainting or loss of consciousness
- fast or irregular breathing
- skin rash
- swelling of the eyes or eyelids
- tightness in the chest or wheezing
- trouble with breathing
Minor Side Effects
Some moxifloxacin ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
- Burning, dry, or itching eyes
- change in vision
- decreased vision
- dry eye
- excessive tearing
- eye discharge
- itching of the eye
- pain in the eye
- red, sore eyes
- redness of the eye
- swelling of the eye, eyelid, or inner lining of the eyelid
- Body aches or pain
- cough or hoarseness
- decreased hearing
- dryness or soreness of the throat
- fever or chills
- general body discomfort
- lower back or side pain
- painful or difficult urination
- rubbing or pulling of the ears (in children)
- runny nose
- sore throat
- tender, swollen glands in the neck
- trouble with swallowing
- voice changes
- vomiting and diarrhea (in infants)
What is the most important information I should know about Moxifloxacin?
- Moxifloxacin may cause dizziness, drowsiness, light-headedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use moxifloxacin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Be sure to use moxifloxacin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Moxifloxacin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to moxifloxacin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
- Nerve problems in the arms, hands, legs, or feet can happen in people taking moxifloxacin. These nerve problems can happen soon after moxifloxacin is started and may be permanent. Call your doctor right away if you have symptoms or nerve problems (eg, not able to handle heat or cold; decreased sensation of touch; unusual burning, numbness, tingling, pain, or weakness of the arms, hands, legs, or feet).
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Severe and sometimes fatal effects have rarely happened with moxifloxacin. These have included muscle or joint, kidney, liver, blood, and other problems. Talk with your doctor if you have questions.
- Moxifloxacin only works against bacteria; it does not treat viral infections (eg, the common cold).
- Do not receive certain live vaccines (oral typhoid vaccine, bacille Calmette-GuÃ©rin [BCG] vaccine) while you are taking moxifloxacin. Talk with your doctor before you receive any vaccine.
- Long-term or repeated use of moxifloxacin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Moxifloxacin has infrequently caused tendon problems, including tendon rupture. If you experience any unusual pain or swelling in your joints (eg, shoulder, elbow, hand, hip, knee, ankle, foot), contact your doctor immediately. Rest and avoid exercise or other physically stressful activity until your doctor tells you otherwise.
- Diabetes patients - Moxifloxacin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Use moxifloxacin with caution in the ELDERLY; they may be more sensitive to its effects (eg, tendon problems), especially if they take corticosteroids (eg, prednisone). They may also be more sensitive to other effects (eg, irregular heartbeat).
- PREGNANCY and BREAST-FEEDING: It is not known if moxifloxacin can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using moxifloxacin while you are pregnant. It is not known if moxifloxacin is found in breast milk. Do not breast-feed while using moxifloxacin.
Known hypersensitivity to moxifloxacin or other quinolones or any of the excipients of Moxifloxacin.
Pregnancy and lactation. Patients <18 years.
Use in pregnancy & lactation: Moxifloxacin is contraindicated in pregnant women.
As with other quinolones, moxifloxacin has been shown to cause lesions in the cartilage of the weight bearing joints of immature animals. Preclinical evidence indicates that small amounts of moxifloxacin may be secreted in human milk. There is no data available in lactating or nursing women. Therefore, the use of moxifloxacin in pregnancy and nursing mothers is contraindicated.
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- HSDB. "Moxifloxacin". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
- NCIt. "Moxifloxacin: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
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- ClinicalTrials.gov. "moxifloxacin". https://clinicaltrials.gov/ (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Moxifloxacin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Moxifloxacin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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Information checked by Dr. Sachin Kumar, MD Pharmacology