Moxifloxacin Side effects

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What are the possible side effects of Moxifloxacin?

Get emergency medical help if you have any of these signs of an allergic reaction: hives, or the first sign of a skin rash; difficult breathing; swelling of your face, lips, tongue, or throat.

Moxifloxacin may cause swelling or tearing of (rupture) a tendon, especially in your ankle. Moxifloxacin can also have serious effects on your nerves, and may cause permanent nerve damage. Stop taking this medicine and call your doctor at once if you have:

  • signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions); or

  • nerve symptoms--numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position.

Stop using moxifloxacin and call your doctor at once if you have:

  • headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;

  • muscle weakness or trouble breathing;

  • diarrhea that is watery or bloody;

  • the first sign of any skin rash, no matter how mild;

  • sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, easy bruising or bleeding, pale or yellowed skin;

  • depression, confusion, hallucinations, paranoia, tremors, feeling restless or anxious, insomnia, nightmares, thoughts about suicide or hurting yourself;

  • seizure (convulsions);

  • high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss;

  • low blood sugar--headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or

  • increased pressure inside the skull-- severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.

Common side effects may include:

  • nausea, diarrhea;

  • dizziness; or

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side effects of Moxifloxacin in details

infoA side effect of any drug can be defined as the unwanted or undesired effect produced by the drug. The side effect can be major or in few medications minor that can be ignored. Side effects not only vary from drug to drug, but it also depends on the dose of the drug, the individual sensitivity of the person, brand or company which manufactures it. If side effects overweigh the actual effect of the medicine, it may be difficult to convince the patient to take the drug. Few patients get specific side effects to specific drugs; in that case, a doctor replaces the drug with another. If you feel any side effect and it troubles you, do not forget to share with your healthcare practitioner.
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Applies to moxifloxacin: oral tablet

In addition to its needed effects, some unwanted effects may be caused by moxifloxacin (the active ingredient contained in Moxifloxacin). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking moxifloxacin:

Rare

  • Abdominal or stomach cramps
  • abdominal or stomach tenderness
  • black, tarry stools
  • bleeding gums
  • blisters
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • blood in the urine or stools
  • blurred vision
  • bone pain
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain
  • chills
  • clay-colored stools
  • cough
  • crying
  • dark urine
  • diarrhea, watery and severe, which may also be bloody
  • difficult or labored breathing
  • difficulty with moving
  • difficulty with swallowing
  • discouragement
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • excessive muscle tone
  • fainting
  • fast, irregular, pounding, or racing heartbeat or pulse
  • feeling of unreality
  • feeling of warmth or heat
  • feeling sad or empty
  • fever
  • flushed, dry skin
  • flushing or redness of the skin, especially on the face and neck
  • fruit-like breath odor
  • headache
  • hyperventilation
  • increased hunger
  • increased sensitivity of the skin to sunlight
  • increased thirst
  • increased urination
  • irregular heartbeat recurrent
  • irritability
  • joint pain, stiffness, or swelling
  • lack of coordination
  • loss of appetite
  • loss of interest or pleasure
  • lower back, side, or stomach pain
  • mood or mental changes
  • muscle aching or cramping
  • muscle pains or stiffness
  • muscle tension or tightness
  • nausea or vomiting
  • nervousness
  • noisy breathing
  • pain
  • pain in the pelvis
  • pain, warmth, or burning in the fingers, toes, and legs
  • painful or difficult urination
  • painful, swollen joints
  • pale skin
  • pinpoint red spots on the skin
  • pounding in the ears
  • problems with speech or speaking
  • problems with vision or hearing
  • quick to react or overreact emotionally
  • rapid weight gain
  • rapidly changing moods
  • redness or other discoloration of the skin
  • restlessness
  • seeing, hearing, or feeling things that are not there
  • seizures
  • sensation of the skin burning
  • sense of detachment from self or body
  • severe sunburn
  • shakiness in the legs, arms, hands, or feet
  • skin rash or itching
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • sweating
  • swelling of the feet or lower legs
  • swelling or puffiness of the face
  • swollen glands
  • tightness in the chest
  • tingling of the hands or feet
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • troubled breathing with exertion
  • unexplained weight loss
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting of blood
  • yellow eyes or skin
Incidence not known:
  • Blistering, peeling, or loosening of the skin
  • burning, numbness, tingling, or painful sensations
  • change in the ability to see colors, especially blue or yellow
  • difficulty with chewing or talking
  • double vision
  • drooping eyelids
  • eye pain
  • general feeling of tiredness or weakness
  • hives
  • hoarseness
  • irregular or slow heart rate
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • muscle weakness
  • no blood pressure or pulse
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red, irritated eyes
  • red skin lesions, often with a purple center
  • severe headache
  • severe tiredness
  • stomach pain, continuing
  • stopping of heart
  • unconsciousness
  • unsteadiness or awkwardness
  • unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness
  • weakness in the arms, hands, legs, or feet

Minor Side Effects

Some of the side effects that can occur with moxifloxacin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Rare

  • Acid or sour stomach
  • bad, unusual, or unpleasant (after) taste
  • belching
  • burning feeling in the chest or stomach
  • change in sense of smell
  • change in taste
  • changes in vision
  • continuing ringing or buzzing or other unexplained noise in the ears
  • difficulty having a bowel movement (stool)
  • excess air or gas in the stomach or intestines
  • fear or nervousness
  • feeling of constant movement of self or surroundings
  • full feeling
  • general feeling of discomfort or illness
  • hearing loss
  • heartburn
  • impaired vision
  • indigestion
  • itching of the vagina or genital area
  • lack or loss of strength
  • loss of memory
  • pain during sexual intercourse
  • passing of gas
  • problems with memory
  • redness, swelling, or soreness of the tongue
  • sensation of spinning
  • sleepiness or unusual drowsiness
  • sore mouth or tongue
  • stomach discomfort, upset, or pain
  • thick, white vaginal discharge with no odor or with a mild odor
  • white patches in the mouth or on the tongue

What is the most important information I should know about Moxifloxacin?

  • Moxifloxacin only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Moxifloxacin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Be sure to use Moxifloxacin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Different brands of Moxifloxacin are approved for different ages of CHILDREN. Follow the instructions that your doctor has provided. If you have any questions about giving Moxifloxacin to your child, check with your doctor or pharmacist.
  • Moxifloxacin should be used with extreme caution in CHILDREN younger than 1 year old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Moxifloxacin while you are pregnant. It is not known if Moxifloxacin is found in breast milk. If you are or will be breast-feeding while you use Moxifloxacin, check with your doctor. Discuss any possible risks to your baby.

Moxifloxacin contraindications

infoContraindication can be described as a special circumstance or a disease or a condition wherein you are not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can be dangerous and life threatening as well. When a procedure should not be combined with other procedure or when a medicine cannot be taken with another medicine, it is called Relative contraindication. Contraindications should be taken seriously as they are based on the relative clinical experience of health care providers or from proven research findings.
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Hypersensitivity to other quinolones, moxifloxacin or any of the excipients of Moxifloxacin.

Use in pregnancy: The safe use of moxifloxacin in human pregnancy has not been established. Reversible joint injuries are described in children receiving some quinolones. However, this effect has not been reported as occurring on exposed foetuses. Animal studies have shown reproductive toxicity. The potential risk for humans is unknown.

Consequently, the use of moxifloxacin during pregnancy is contraindicated.

Use in lactation: As with other quinolones, moxifloxacin has been shown to cause lesions in the cartilage of the weight bearing joints of immature animals. Preclinical evidence indicates that small amounts of moxifloxacin may be secreted in human milk. There is no data available in lactating or nursing women. Therefore, the use of moxifloxacin in nursing mothers is contraindicated.

Use in children: Safety and efficacy of moxifloxacin in children and adolescents have not been established.


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References

  1. European Chemicals Agency - ECHA. "1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-on-ch... (accessed September 18, 2017).
  2. HSDB. "Moxifloxacin". https://toxnet.nlm.nih.gov/cgi-bin/sis/s... (accessed September 18, 2017).

Reviews

The results of a survey conducted on ndrugs.com for Moxifloxacin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Moxifloxacin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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