Mozal Uses

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What is Mozal?

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent wheezing caused by exercise (exercise-induced bronchospasm).

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, albuterol is used in certain patients with the following medical condition:

Mozal indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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As a bronchodilator in the treatment of bronchospasm associated with bronchial asthma, emphysema and chronic bronchitis and other conditions associated with reversible airways obstruction. Mozal also decreases uterine contractility and arrests premature labor.

Uses of Mozal in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Mozal is used to prevent reversible airways obstruction occurring during asthma, infections of airway passages (bronchitis), lung disorder in which the flow of air to the lungs is blocked (emphysema), and other lung diseases.

Mozal description

Each 200 mcg/dose powder for inhalation solution contains Salbutamol sulphate equivalent to Mozal 200 mcg per metered dose. The dose, which the patient gets through the mouthpiece of the device is Mozal 180 mcg.

It contains lactose monohydrate (milk protein) as excipient.

The Mozal multiple dose powder inhaler contains 200 doses of finely powdered Mozal sulphate mixed in a small quantity of lactose. The amount of drug received by the patient (180 mcg/dose) corresponds to that from Mozal inhalation aerosol. The dose to be inhaled is released from the container by pressing the device between the thumb and forefinger. This is followed by inhalation through the device. As a result, Mozal particles are transferred to their target, the lungs. Use of the Mozal does not require coordination of actuation of the dose and inhalation.

Mozal dosage

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Tablet: Adults: Usual Dose: 4 mg or 10 mL (2 tsp) of syrup. If adequate bronchodilation is not obtained, each single dose may be gradually increased to as much as 8 mg or 20 mL (4 tsp) of syrup.

To be taken every 6 or 8 hrs.

In some patients known to be unusually sensitive to β-adrenergic stimulant drugs who obtain adequate relief with 5 mL of syrup, it is advisable to initiate treatment with 5 mL (1 tsp) of syrup 3 or 4 times a day.

Children >12 years: 2-4 mg or 5-10 mL (1-2 tsp) of syrup; 6-12 years: 2 mg or 5 mL (1 tsp) of syrup; 2-6 years: 1-2 mg or 2.5-5 mL (½-1 tsp) of syrup.

Nebulizing Solution: Adults and Adolescents: Usual Dose: The usual initial dose of Mozal by wet inhalation is 2.5-5 mg. Treatment may be repeated up to 4 times daily. In adults, higher dosing up to 40 mg/day can be given under strict medical supervision in hospital for the treatment of severe airway obstruction.

Children up to 12 years: Dosage has not been established. Note: As there may be adverse effects associated with excessive dosing, the dosage or frequency of administration should only be increased on medical advice.

Administration: Mozal 1 mg/mL nebulizing solution for inhalation is given undiluted using a nebulizer, under the direction of a physician. However, if prolonged administration is desired (>10 min), the solution can be diluted with 0.9% sodium chloride solution.

Direction for Dilution/Prolonged Inhalation: Pipette 2.5-5 mL (equivalent to 2.5-5 mg Mozal, as sulfate) of Mozal nebulizing solution from the bottle by using a calibrated medicine dropper provided in the pack. Drop the solution into an electric nebulizer and dilute it with 2-4 mL normal saline solution and start inhalation. Any unused solution in the chamber of the nebulizer must be discarded. Repeat the same procedure every 8 hrs in a 24-hr period.

Mozal interactions

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If additional adrenergic drugs are administered to patients using Mozal Easyhaler they should be used with caution to avoid deleterious cardiovascular effects. Patients treated with monoamine oxidase inhibitors or tricyclic antidepressants should be followed clinically in the beginning of Mozal treatment, because the action of Mozal on the vascular system may be potentiated. Beta-blockers eg, propranolol, inhibit the effect of Mozal like that of any other β2-agonists.

The simultaneous administration of xanthines, corticosteroids or potassium excreting diuretics may increase hypokalemia.

Incompatibilities: Not applicable.

Mozal side effects

See also:
What are the possible side effects of Mozal?

Mozal sulfate is generally well tolerated and serious toxic effects are few. The adverse reactions to Mozal sulfate are similar in nature to reactions to other sympathomimetic agents, although the incidence of certain cardiovascular effects is lower with Mozal sulfate. The most frequent adverse reactions to Mozal sulfate are nervousness and tremor. Other reported reactions are headache, tachycardia and palpitations, muscle cramps, insomnia, nausea, weakness and dizziness. Rare cases of urticaria, angioedema, rash and oropharyngeal edema have been reported after the use of Mozal sulfate. The reactions are generally transient in nature and it is usually not necessary to discontinue treatment with Mozal sulfate. Inform the physician of the unwanted effects after administering.

Mozal contraindications

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Hyperthyroidism and cardiac disease. Mozal may interact with monoamine oxidase inhibitors and should not be given to patients receiving such treatment or within 14 days after stopping treatment.

Use in pregnancy & lactation: Safety in pregnancy and lactating women has not been established.

Mozal is not indicated for the prevention of premature labor associated with toxemia of pregnancy or ante partum hemorrhage, nor should it be used for threatened abortion during the 1st and 2nd trimesters of pregnancy.

Active ingredient matches for Mozal:

Salbutamol in Taiwan.


Unit description / dosage (Manufacturer)Price, USD
Mozal 4 mg x 100's
Mozal 4 mg x 500's
Mozal 4 mg x 1000's

List of Mozal substitutes (brand and generic names):

Nefty S 1000+500 Injection (Neuron Pharma Pvt. Ltd.)$ 1.33
New Ventiphyline 2+157.23 Tablet (Yash Pharma International)$ 0.01
New Ventiphyline Forte 4+314.46 Tablet (Yash Pharma International)$ 0.01
Nioxol 100 ml Syrup (Woodrock Healthcare Pvt. Ltd.)$ 0.02
Nioxol S 100 ml Syrup (Woodrock Healthcare Pvt. Ltd.)$ 0.02
Nopant 6 mg/1 mL x 20 mL
Onimar PD 100 ml Syrup (Emcee Pharmaceuticals Pvt.Ltd.)$ 0.01
ONIMAR PD 50 MG/1 MG SYRUP 1 bottle / 100 ML syrup each (Emcee Pharmaceuticals Pvt.Ltd.)$ 0.39
Onimar PD 50 mg/1 mg Syrup (Emcee Pharmaceuticals Pvt.Ltd.)$ 0.39
Ophyl TR 300 mg Tablet (Octane Biotech Pvt. Ltd.)$ 0.23
Solution; Inhalation; Albuterol Sulfate
Aerosol, Metered-Dose; Inhalation; Albuterol Sulfate 50 mcg / dose (Penta)
Pharmaniaga Salbutamol 4 mg x 50 x 10's (Pharmaniaga Manufacturing Berhad)
Pharmaniaga Salbutamol 2 mg/5 mL x 90 mL (Pharmaniaga Manufacturing Berhad)
Pharmaniaga Salbutamol syr 2 mg/5 mL 90 mL x 1's (Pharmaniaga Manufacturing Berhad)
Pharmaniaga Salbutamol tab 4 mg 50 x 10's (Pharmaniaga Manufacturing Berhad)
Solution; Oral; Albuterol Sulfate 0.4 mg / ml
Solution; Oral; Albuterol Sulfate 0.5 mg / ml
Solution; Oral; Albuterol Sulfate 1 mg / ml
Solution; Oral; Albuterol Sulfate 2 mg / ml
Solution; Oral; Albuterol Sulfate 5 mg / ml
Solution; Inhalation; Salbutamol Sulfate 0.5 mg / ml
Solution; Inhalation; Salbutamol Sulfate 1 mg / ml
Solution; Inhalation; Salbutamol Sulfate 2 mg / ml
Solution; Inhalation; Oral; Salbutamol Sulfate 5 mg / ml
PMS-salbutamol solution 5 mg (Pharmascience Inc (Canada))

References

  1. DailyMed. "ALBUTEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Salbutamol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Salbutamol". http://www.drugbank.ca/drugs/DB01001 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Mozal are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mozal. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Mozal drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


1 consumer reported time for results

To what extent do I have to use Mozal before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Mozal. To get the time effectiveness of using Mozal drug by other patients, please click here.
Users%
5 days1
100.0%


1 consumer reported age

Users%
30-451
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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