Mébévérine Uses

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Mébévérine indications

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Irritable bowel syndrome & allied conditions eg, chronic irritable colon, spastic constipation, mucous colitis and spastic colitis. Symptomatic treatment of abdominal pain, cramps, nonspecific diarrhoea & flatulence. GI spasm secondary to organic diseases eg, diverticulitis, gastritis, duodenitis, oesophagitis, cholecystitis, Crohn's disease, ulcerative colitis, peptic ulcer, gallbladder disease, hiatus hernia, GIT inflammation.

Uses of Mébévérine in details

Mébévérine is used to treat irritable bowel syndrome (disorder of the intestines that leads to cramps in the abdomen, gas, bloating and changes in bowel habits). It is also used to treat other conditions that involve spasm and pain related to small and large bowel.

Mébévérine description

Each capsule contains Mébévérine HCl 200 mg.

Mébévérine also contains the following excipients: Capsule Content (Granules): Magnesium stearate, polyacrylate dispersion 30%, talc, hypromellose, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion 30% and glycerol triacetate. Capsule Shell: Gelatin, titanium dioxide (E171). Printing Ink: Shellac (E904), black iron oxide (E172), propylene glycol, concentrated ammonia solution, potassium hydroxide.

Mébévérine dosage

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Adults: 1 capsule twice daily (1 in the morning and 1 in the evening).

Special Populations: Elderly, Renal and Hepatic Impairment: No posology studies in elderly, renal and/or hepatically impaired patients have been performed. However, no specific risk for elderly, renal and/or hepatically impaired patients could be identified from available post-marketing data. No dosage adjustment is deemed necessary in these patients.

Missed Dose: In case of ≥1 doses missed, continue with the next dose as prescribed; the missed doses are not to be taken in addition to the regular dose.

Administration: The capsules should be swallowed with a sufficient amount of water (at least 100 mL of water).

It should not be chewed because the coating is intended to ensure a prolonged release mechanism.

Mébévérine interactions

No interaction studies have been performed except with alcohol. In vitro and in vivo studies in animals have demonstrated the absence of any interaction between Mébévérine and ethanol.

Incompatibilities: Not applicable.

Mébévérine side effects

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Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Rarely, allergic reactions such as rashes, hives, or severe swelling of lips, face or tongue (angioedema).

The side effects listed above may not include all of the side effects reported by the medicine’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Mébévérine contraindications

Hypersensitivity to Mébévérine HCl or to any of the excipients of Mébévérine.

Active ingredient matches for Mébévérine:

Mébévérine


Unit description / dosage (Manufacturer)Price, USD
Capsule; Oral; Mebeverine Hydrochloride 100 mg
Capsule; Oral; Mebeverine Hydrochloride 200 mg
Tablet, Sugar-Coated; Oral; Mebeverine Hydrochloride 135 mg

List of Mébévérine substitutes (brand and generic names):

MEVA CAPSULE SR 1 strip / 10 capsule srs each (Zydus (Alidac))$ 1.57
MEVA SR cap 200 mg x 10's (Zydus (Alidac))$ 1.30
Meva 200mg Capsule SR (Zydus (Alidac))$ 0.17
MOREASE Capsule/ Tablet / 135mg / 10 units (Dr. Reddy's)$ 0.59
Morease 135mg TAB / 10 (Dr. Reddy's)$ 0.57
135 mg x 10's (Dr. Reddy's)$ 0.57
MOREASE 135 MG TABLET 1 strip / 10 tablets each (Dr. Reddy's)$ 0.89
MOREASE 200 MG CAPSULE SR 1 strip / 10 capsule srs each (Dr. Reddy's)$ 0.89
MOREASE tab 135 mg x 10's (Dr. Reddy's)$ 0.68
MOREASE SR cap 200 mg x 10's (Dr. Reddy's)$ 0.99
Morease 135mg TAB / 10 (Dr. Reddy's)$ 0.57
Morease 135mg Tablet (Dr. Reddy's)$ 0.09
Morease 200mg Capsule SR (Dr. Reddy's)$ 0.14
NORMAXIN MB 200 MG TABLET 1 strip / 10 tablets each (Systopic Laboratories Pvt Ltd)$ 0.95
Normaxin MB 200mg Capsule (Systopic Laboratories Pvt Ltd)$ 0.10
Padalin 100 mg
Sulson 100 mg
Verimed 135 mg x 5 Blister x 10 Tablet

References

  1. PubChem. "mebeverine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Mebeverine". http://www.drugbank.ca/drugs/DB12554 (accessed September 17, 2018).
  3. MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Mébévérine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mébévérine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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