Neo-Collargol Suppositories Uses

How do you administer this medicine?
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Consists of Epinephrine, Procaine, Silver

What is Epinephrine (Neo-Collargol Suppositories)?

Epinephrine (Neo-Collargol Suppositories) is an injection containing Epinephrine (Neo-Collargol Suppositories), a chemical that narrows blood vessels and opens airways in the lungs. These effects can reverse severe low blood pressure, wheezing, severe skin itching, hives, and other symptoms of an allergic reaction.

Epinephrine (Neo-Collargol Suppositories) is used to treat severe allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs, and other allergens. Epinephrine (Neo-Collargol Suppositories) is also used to treat exercise-induced anaphylaxis.

Epinephrine (Neo-Collargol Suppositories) auto-injectors such as Epinephrine (Neo-Collargol Suppositories) and Epinephrine (Neo-Collargol Suppositories) Jr. may be kept on hand for self-injection by a person with a history of an severe allergic reaction.

Epinephrine (Neo-Collargol Suppositories) may also be used for purposes not listed in this medication guide.

Epinephrine (Neo-Collargol Suppositories) indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Epinephrine (Neo-Collargol Suppositories) and Epinephrine (Neo-Collargol Suppositories) Jr are indicated in the emergency treatment of allergic reactions (Type I) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g., radiocontrast media) and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.

Epinephrine (Neo-Collargol Suppositories) and Epinephrine (Neo-Collargol Suppositories) Jr are intended for immediate administration in patients who are determined to be at increased risk for anaphylaxis, including individuals with a history of anaphylactic reactions.

Anaphylactic reactions may occur within minutes after exposure and consist of flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with a fall in blood pressure, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, wheezing, dyspnea due to laryngeal spasm, pruritus, rashes, urticaria or angioedema.

Epinephrine (Neo-Collargol Suppositories) and Epinephrine (Neo-Collargol Suppositories) Jr are intended for immediate administration as emergency supportive therapy only and are not a substitute for immediate medical care.

How should I use Epinephrine (Neo-Collargol Suppositories)?

Use Epinephrine (Neo-Collargol Suppositories) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Epinephrine (Neo-Collargol Suppositories).

Uses of Epinephrine (Neo-Collargol Suppositories) in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Acute asthma, anaphylactic shock, advanced cardiac life support, ocular hypertension, open angle glaucoma.

Epinephrine (Neo-Collargol Suppositories) description

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Epinephrine (Neo-Collargol Suppositories) may also cause sterility, birth defects, mutations, and cancer.

Epinephrine (Neo-Collargol Suppositories) dosage

Selection of the appropriate dosage strength (Epinephrine (Neo-Collargol Suppositories) 0.3 mg or Epinephrine (Neo-Collargol Suppositories) Jr 0.15 mg) is determined according to patient body weight.

Inject Epinephrine (Neo-Collargol Suppositories) or Epinephrine (Neo-Collargol Suppositories) Jr intramuscularly or subcutaneously into the anterolateral aspect of the thigh, through clothing if necessary. Instruct caregivers of young children who are prescribed an Epinephrine (Neo-Collargol Suppositories) or Epinephrine (Neo-Collargol Suppositories) Jr and who may be uncooperative and kick or move during an injection to hold the leg firmly in place and limit movement prior to and during an injection.

Each Epinephrine (Neo-Collargol Suppositories) or Epinephrine (Neo-Collargol Suppositories) Jr contains a single dose of Epinephrine (Neo-Collargol Suppositories) for single-use injection. Since the doses of Epinephrine (Neo-Collargol Suppositories) delivered from Epinephrine (Neo-Collargol Suppositories) or Epinephrine (Neo-Collargol Suppositories) Jr are fixed, consider using other forms of injectable Epinephrine (Neo-Collargol Suppositories) if doses lower than 0.15 mg are deemed necessary.

The prescriber should carefully assess each patient to determine the most appropriate dose of Epinephrine (Neo-Collargol Suppositories), recognizing the life-threatening nature of the reactions for which this drug is indicated. Wit h severe persist ent anaph yl ax is, repeat injections with an additional EpiP en or Epinephrine (Neo-Collargol Suppositories) Jr ma y be necessary. More than two sequential doses of Epinephrine (Neo-Collargol Suppositories) should only be administered under direct medical supervision.

The Epinephrine (Neo-Collargol Suppositories) solution in the clear window of t he Epinephrine (Neo-Collargol Suppositories) should be inspected visually for particulate matter and discoloration. Epinephrine (Neo-Collargol Suppositories) is light sensitive and should be stored in the carrier tube provided to protect it from light.

How supplied

Dosage Forms And Strengths

Epinephrine (Neo-Collargol Suppositories) Auto-Injectors (Epinephrine (Neo-Collargol Suppositories) injections, USP, 1:1000, 0.3 mL) are available as Epinephrine (Neo-Collargol Suppositories) 2Pak®, NDC 49502-500-02, a pack that contains two Epinephrine (Neo-Collargol Suppositories) Auto-Injectors (Epinephrine (Neo-Collargol Suppositories) injections, USP, 1:1000, 0.3 mL) and one Epinephrine (Neo-Collargol Suppositories) trainer device.

Epinephrine (Neo-Collargol Suppositories) Jr Auto-Injectors (Epinephrine (Neo-Collargol Suppositories) injections, USP, 1:2000, 0.3 mL) are available as Epinephrine (Neo-Collargol Suppositories) Jr 2-Pak®, NDC 49502-501-02, a pack that contains two Epinephrine (Neo-Collargol Suppositories) Jr Auto-Injectors (Epinephrine (Neo-Collargol Suppositories) injections, USP, 1:2000, 0.3 mL) and one Epinephrine (Neo-Collargol Suppositories) trainer device.

Epinephrine (Neo-Collargol Suppositories) 2-Pak® and Epinephrine (Neo-Collargol Suppositories) Jr 2-Pak® also include an S-clip to clip two carrier tubes together.

Storage And Handling

Protect from light. Epinephrine (Neo-Collargol Suppositories) is light sensitive and should be stored in the carrier tube provided to protect it from light. Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). Do not refrigerate. Before using, check to make sure the solution in the auto-injector is clear and colorless. Replace the auto-injector if the solution is discolored (pinkish or brown color), cloudy, or contains particles.

Manufactured for Mylan Specialty L.P., Morgantown, WV 26505, U.S.A. by Meridian Medical Technologies, Inc., Columbia, MD 21046, U.S.A., a Pfizer company. Revised: May 2016

Epinephrine (Neo-Collargol Suppositories) interactions

See also:
What other drugs will affect Epinephrine (Neo-Collargol Suppositories)?

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Alpha-adrenergic blocking agents (eg, phentolamine), ergot derivative (eg, ergotamine), nitrites, phenothiazines (eg, chlorpromazine)

May counteract the Epinephrine (Neo-Collargol Suppositories) pressor effects.

Antihistamines (eg, chlorpheniramine, diphenhydramine), COMT inhibitors (eg, entacapone, tolcapone), levothyroxine, linezolid, MAOIs (eg, phenelzine), tricyclic antidepressants (amitriptyline)

Epinephrine (Neo-Collargol Suppositories) effects may be potentiated.

Beta-adrenergic blockers (eg, propranolol)

Beta-adrenergic effects of Epinephrine (Neo-Collargol Suppositories) may be blocked, resulting in hypertension.

Diuretics

May decrease vascular response to Epinephrine (Neo-Collargol Suppositories).

Drugs that sensitize the heart to arrhythmias (eg, antiarrhythmics, digitalis, diuretics, quinidine)

Epinephrine (Neo-Collargol Suppositories) may precipitate or aggravate angina pectoris or produce ventricular arrhythmias.

Furazolidone, methyldopa, rauwolfia alkaloids (eg, alseroxylon, rauwolfia)

Risk of hypertension may be increased.

General anesthetics (eg, cyclopropane, halothane)

Coadministration is contraindicated; may induce cardiac arrhythmias.

Guanethidine

Neuronal blockade may be antagonized by Epinephrine (Neo-Collargol Suppositories), resulting in decreased antihypertensive effect and requiring subsequent dosage adjustments.

Oxytocic drugs

Severe persistent hypertension may occur; rupture of a cerebral blood vessel may occur during the postpartum period.

Sympathomimetic agents (eg, isoproterenol)

Possible additive effects and increased toxicity (eg, serious cardiac arrhythmias); administer alternatively when the preceding effect of the other drug has subsided, not concurrently.

Epinephrine (Neo-Collargol Suppositories) side effects

See also:
What are the possible side effects of Epinephrine (Neo-Collargol Suppositories)?

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Due to the lack of randomized, controlled clinical trials of Epinephrine (Neo-Collargol Suppositories) for the treatment of anaphylaxis, the true incidence of adverse reactions associated with the systemic use of Epinephrine (Neo-Collargol Suppositories) is difficult to determine. Adverse reactions reported in observational trials, case reports, and studies are listed below.

Common adverse reactions to systemically administered Epinephrine (Neo-Collargol Suppositories) include anxiety; apprehensiveness; restlessness; tremor; weakness; dizziness; sweating; palpitations; pallor; nausea and vomiting; headache; and/or respiratory difficulties. These symptoms occur in some persons receiving therapeutic doses of Epinephrine (Neo-Collargol Suppositories), but are more likely to occur in patients with hypertension or hyperthyroidism.

Arrhythmias, including fatal ventricular fibrillation, have been reported, particularly in patients with underlying cardiac disease or those receiving certain drugs.

Rapid rises in blood pressure have produced cerebral hemorrhage, particularly in elderly patients with cardiovascular disease.

Angina may occur in patients with coronary artery disease.

Accidental injection into the digits, hands or feet may result in loss of blood flow to the affected area.

Adverse events experienced as a result of accidental injections may include increased heart rate, local reactions including injection site pallor, coldness and hypoesthesia or injury at the injection site resulting in bruising, bleeding, discoloration, erythema or skeletal injury.

Lacerations, bent needles, and embedded needles have been reported when Epinephrine (Neo-Collargol Suppositories) has been injected into the thigh of young children who are uncooperative and kick or move during the injection.

Injection into the buttock has resulted in cases of gas gangrene.

Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by Clostridia (gas gangrene), have been reported following Epinephrine (Neo-Collargol Suppositories) injection, including Epinephrine (Neo-Collargol Suppositories), in the thigh.

Epinephrine (Neo-Collargol Suppositories) contraindications

See also:
What is the most important information I should know about Epinephrine (Neo-Collargol Suppositories)?

Before using this medication, tell your doctor if you have heart disease or high blood pressure, a heart rhythm disorder, coronary artery disease, Parkinson's disease, diabetes, or a thyroid disorder.

Before using Epinephrine (Neo-Collargol Suppositories), tell your doctor about all other medications you use, especially digoxin (digitalis, Lanoxin), heart or blood pressure medicine, heart rhythm medication, an antidepressant, a diuretic (water pill), thyroid medication, migraine headache medicine, cold or sleep medicine that contains an antihistamine, or an MAO inhibitor such as Marplan, Nardil, Azilect, Eldepryl, Emsam, or Parnate.

Seek emergency medical attention even after you use Epinephrine (Neo-Collargol Suppositories) to treat a severe allergic reaction. The effects of Epinephrine (Neo-Collargol Suppositories) may wear off after 10 or 20 minutes. You will need to receive further treatment and observation.

Before using Epinephrine (Neo-Collargol Suppositories) a second time, tell your doctor if your first injection caused a serious side effect such as increased breathing difficulty, or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

What is Procaine (Neo-Collargol Suppositories)?

Procaine (Neo-Collargol Suppositories) (Procaine (Neo-Collargol Suppositories)) is a local anesthetic. Procaine (Neo-Collargol Suppositories) causes loss of feeling (numbness) of skin and mucous membranes.

Procaine (Neo-Collargol Suppositories) is used as an injection during surgery and other medical and dental procedures.

Procaine (Neo-Collargol Suppositories) may also be used for purposes other than those listed here.

Procaine (Neo-Collargol Suppositories) indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Injection

Percutaneous infiltration anaesthesia

Adult: 350-600 mg using 0.25 or 0.5% solutions.

Injection

Peripheral nerve block

Adult: 500 mg Procaine (Neo-Collargol Suppositories) HCl as a 0.5%, 1% or 2% solution. Up to 1 g may be used.

How should I use Procaine (Neo-Collargol Suppositories)?

Your healthcare provider will administer Procaine (Neo-Collargol Suppositories) as an injection.

Uses of Procaine (Neo-Collargol Suppositories) in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Procaine (Neo-Collargol Suppositories) is used for inducing local anaesthesia (loss of sensation) during surgical operations, dental procedures or other such medical procedures.

Procaine (Neo-Collargol Suppositories) description

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).

Procaine (Neo-Collargol Suppositories) dosage

Procaine (Neo-Collargol Suppositories) Dosage

Generic name: Procaine (Neo-Collargol Suppositories) hydrochloride

Dosage form: injection, USP

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

As with all local anesthetics, the dose of Procaine (Neo-Collargol Suppositories) varies and depends upon the area to be anesthetized, the vascularity of the tissues, the number of neuronal segments to be blocked, individual tolerance, and the technique of anesthesia. The lowest dose needed to provide effective anesthesia should be administered. For specific techniques and procedures, refer to standard textbooks.

RECOMMENDED DOSAGE FOR SPINAL ANESTHESIA
Extent of Anesthesia Procaine (Neo-Collargol Suppositories)

10% Solution

Total Dose

(mg)

Site of Injection

(lumbar interspace)

Volume of 10% Solution

(mL)

Volume of Dilution

(mL)

Perineum 0.5 0.5 50 4th
Perineum and lower

extremities

1 1 100 3rd or 4th
Up to costal margin 2 1 200 2nd, 3rd or 4th

The diluent may be sterile normal saline, sterile distilled water, spinal fluid; and for hyperbaric technique, sterile dextrose solution.

The usual rate of injection is 1 mL per 5 seconds. Full anesthesia and fixation usually occur in 5 minutes.

STERILIZATION

The drug in intact ampuls is sterile. The preferred method of destroying bacteria on the exterior of ampuls before opening is heat sterilization (autoclaving). Immersion in antiseptic solution is not recommended.

Autoclave at 15-pound pressure, at 121°C (250°F), for 15 minutes. The diluent dextrose may show some brown discoloration due to caramelization.

Protect solutions from light.

More about Procaine (Neo-Collargol Suppositories) (Procaine (Neo-Collargol Suppositories))

Professional resources

Related treatment guides

Procaine (Neo-Collargol Suppositories) interactions

See also:
What other drugs will affect Procaine (Neo-Collargol Suppositories)?

Anticholinesterases

Concurrent use of Procaine (Neo-Collargol Suppositories) hydrochloride and anticholinesterase agents may result in increased systemic toxicity since anticholinesterases inhibit the breakdown of Procaine (Neo-Collargol Suppositories) hydrochloride.

Antimyasthenics

Concurrent use of Procaine (Neo-Collargol Suppositories) hydrochloride and antimyasthenics may result in loss of control of symptoms of myasthenia gravis due to antagonism of the effects of antimyasthenics on skeletal muscle. Temporary dosage adjustment of antimyasthenics may be required. Also antimyasthenics may have anticholinesterase activity.

CNS depressant medications

Concurrent use of Procaine (Neo-Collargol Suppositories) hydrochloride and CNS depressant medications may result in additive depressant effects.

Hyaluronidase

Hyaluronidase may increase the diffusion rate of Procaine (Neo-Collargol Suppositories) hydrochloride, resulting in a decreased time of onset, but an increase in systemic toxicity.

Neuromuscular blocking agents (such as suxamethonium chloride)

Concurrent use of Procaine (Neo-Collargol Suppositories) hydrochloride and neuromuscular blocking agents may result in prolongation or enhancement of the neuromuscular blockade.

Sulfonamides

Concurrent use of Procaine (Neo-Collargol Suppositories) hydrochloride and sulfonamides may result in a reduction of the antibacterial action of the sulfonamide.

Acetazolamide

Concurrent use of acetazolamide and Procaine (Neo-Collargol Suppositories) hydrochloride may extend the plasma half-life of Procaine (Neo-Collargol Suppositories).

Procaine (Neo-Collargol Suppositories) side effects

See also:
What are the possible side effects of Procaine (Neo-Collargol Suppositories)?

Reactions to Procaine (Neo-Collargol Suppositories) are characteristic of those associated with other ester-type local anesthetics. A major cause of adverse reactions to this group of drugs is excessive plasma levels which may be due to overdosage, rapid absorption, inadvertent intravascular injection, or slow metabolic degradation.

A small number of reactions may result from hypersensitivity, idiosyncrasy, or diminished tolerance to normal dosage.

Systemic:

The most commonly encountered acute adverse experiences which demand immediate countermeasures are related to the central nervous system and the cardiovascular system. These adverse experiences are generally dose related and due to high plasma levels which may result from overdosage, rapid absorption from the injection site, diminished tolerance, or from unintentional intravascular injection of the local anesthetic solution. In addition to systemic dose-related toxicity, unintentional subarachnoid injection of drug during the intended performance of nerve blocks near the vertebral column (especially in the head and neck region), may result in underventilation or apnea (“Total or High Spinal”). Factors influencing plasma protein binding, such as acidosis, systemic diseases which alter protein production, or competition of other drugs for protein binding sites may diminish individual tolerance.

Plasma cholinesterase deficiency may also account for diminished tolerance to ester-type local anesthetics.

Central Nervous System Reactions:

These are characterized by excitation and/or depression. Restlessness, anxiety, dizziness, tinnitus, blurred vision, or tremors may occur, possibly proceeding to convulsions. However, excitement may be transient or absent, with depression being the first manifestation of an adverse reaction. This may quickly be followed by drowsiness merging into unconsciousness and respiratory arrest.

The incidence of convulsions associated with the use of local anesthetics varies with the procedure used and the total dose administered.

Cardiovascular Reactions:

High doses or inadvertent intravascular injection may lead to high plasma levels and related depression of the myocardium, decreased cardiac output, heartblock, hypotension (or sometimes hypertension), bradycardia, ventricular arrhythmias, and cardiac arrest.

Allergic:

Allergic-type reactions are rare and may occur as a result of sensitivity to the local anesthetic or to other formulation ingredients, such as the antimicrobial preservative chlorobutanol contained in multiple-dose vials. These reactions are characterized by signs such as urticaria, pruritus, erythema, angioneurotic edema (including laryngeal edema), tachycardia, sneezing, nausea, vomiting, dizziness, syncope, excessive sweating, elevated temperature, and, possibly, anaphylactoid-like symptomatology (including severe hypotension). Cross sensitivity among members of the ester-type local anesthetic group has been reported. The usefulness of screening for sensitivity has not been definitely established.

Neurologic:

The incidences of adverse neurologic reactions associated with the use of local anesthetics may be related to the total dose of local anesthetic administered, and are also dependent upon the particular drug used, the route of administration, and the physical status of the patient. Many of these effects may be related to local anesthetic techniques, with or without a contribution from the drug.

Procaine (Neo-Collargol Suppositories) contraindications

See also:
What is the most important information I should know about Procaine (Neo-Collargol Suppositories)?

Spinal anesthesia with Procaine (Neo-Collargol Suppositories) is contraindicated in patients with generalized septicemia: sepsis at the proposed injection site; certain diseases of the cerebrospinal system, e.g., meningitis, syphilis; and a known hypersensitivity to the drug, drugs of a similar chemical configuration, or aminobenzoic acid or its derivatives.

The decision as to whether or not spinal anesthesia should be used in an individual case should be made by the physician after weighing the advantages with the risks and possible complications.

Silver (Neo-Collargol Suppositories) indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

medicated dressing for infected wounds

Uses of Silver (Neo-Collargol Suppositories) in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Use: Labeled Indications

Wound management:

Topical anti-infective used in the management of first- or second-degree burns and wounds (including abrasions; device insertion wounds; lacerations, skin tears, and/or superficial wounds; donor, graft, and/or surgical incision sites; diabetic, pressure, and/or stasis ulcers).

Silver (Neo-Collargol Suppositories) dosage

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Gel, External:

Arida: (25 g, 45 g, 100 g, 500 g, 1000 g, 5000 g, 25000 g)

BasaDrox: (5 mL)

Silver (Neo-Collargol Suppositories): (42 g)

Elta SilverGel: (45 mL [DSC], 473 mL [DSC])

Protyl Ag: 1% (42 g)

SilvaSorb: (44.4 mL)

Solox: (45 mL) [contains trolamine (triethanolamine)]

Pad, External:

Aceso Ag: 4"X4" (4 ea)

Silverseal Hydrogel Dressing: 2"X3" (1 ea, 10 ea); 4"X5" (1 ea, 10 ea) [contains methylparaben, propylparaben]

Tegaderm Ag Mesh: 2"X2" (1 ea); 4"X5" (1 ea); 4"X8" (1 ea); 8"X8" (1 ea)

Dosing: Adult

Wound Management: Note: General dosing considerations presented; consult full manufacturers labeling prior to use. Assess need for continued treatment after 2 weeks of therapy. Once the infection is under control and the wound is healing, consider a change to a nonantimicrobial dressing (International Consensus 2012).

Dressing:

Topical:

3M Tegaderm Ag Mesh: Apply directly to wound; change as needed. Dressing remains effective for up to 7 days.

Silver (Neo-Collargol Suppositories), Silver (Neo-Collargol Suppositories) 7: Apply directly to wound; Silver (Neo-Collargol Suppositories) 7 may be left in place for up to 7 days.

Silver (Neo-Collargol Suppositories) Flex: Apply directly to wound. Silver (Neo-Collargol Suppositories) Flex 3 may be left in place for up to 3 days; Silver (Neo-Collargol Suppositories) Flex 7 may be left in place for up to 7 days.

Silver (Neo-Collargol Suppositories) Moisture Control, Silver (Neo-Collargol Suppositories) Site, Silver (Neo-Collargol Suppositories) Surgical: Apply directly to wound. Change dressing as needed; may remain in place for up to 7 days.

Restore: Apply directly to wound; change as needed.

Silverseal: Apply directly to wound; change within 7 days.

SilvrSTAT: Apply directly to wound; change every 24 to 72 hours or as needed.

Gel:

Topical:

RevitaDERM, Solox: Apply / inch thick layer to wound.

Dosing: Geriatric

Refer to adult dosing.

Silver (Neo-Collargol Suppositories) interactions

There are no known significant interactions.

Silver (Neo-Collargol Suppositories) side effects

See also:
What are the possible side effects of Silver (Neo-Collargol Suppositories)?

Adverse Reactions

Frequency not defined.

Dermatologic: Allergic skin reaction, erythema, skin cyanosis, local discoloration (temporary black discoloration at application site)

Local: Application site irritation

Silver (Neo-Collargol Suppositories) contraindications

Hypersensitivity to Silver (Neo-Collargol Suppositories) or any component of the formulation.

3M Tegaderm Ag Mesh: Hypersensitivity to cotton; application to third-degree burns; use as a surgical sponge; use with enzymatic debriding agents that are contraindicated with Silver (Neo-Collargol Suppositories) products

Silver (Neo-Collargol Suppositories), Silver (Neo-Collargol Suppositories) Flex 3 and 7, Silver (Neo-Collargol Suppositories) Surgical: Use during magnetic resonance imaging (MRI) or radiation therapy

Silver (Neo-Collargol Suppositories) Moisture Control: Use during MRI

Silver (Neo-Collargol Suppositories) Site: Hypersensitivity to polyurethane; use during MRI

Restore: Hypersensitivity to alginates; application to third-degree burns; surgical implantation; to control heavy bleeding; use on dry or lightly exuding wounds

Silverseal Hydrogel: Hypersensitivity to nylon; use with cardiac defibrillators



Active ingredient matches for Neo-Collargol Suppositories:

Epinephrine/Procaine/Silver


Unit description / dosage (Manufacturer)Price, USD
Suppositories; Rectal; Epinephrine; Procaine; Silver Colloidal

List of Neo-Collargol Suppositories substitutes (brand and generic names):

References

  1. DailyMed. "EPINEPHRINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "epinephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "procaine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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