Neofollin Pregnancy

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Pregnancy of Neofollin in details

Pregnancy is always a special situation where every action or side effect of the drug varies when compared to a situation of a non-pregnant patient. It is not only because the pregnant woman's metabolism differs due to the hormonal and other changes happened to her, but also because every medicine or its metabolite passes to the baby and shows its action there. The only thing is, be cautious, attentive and well supervised when you take any single drug in pregnancy. The interactions can vary in pregnancy, and the dosage may differ as well. Strict supervision of the Physician is mandatory.
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Estrogenic agents have been associated with urogenital abnormalities in offspring that manifest later in life. Vaginal adenosis, squamous cell dysplasia of the uterine cervix and vaginal cancer have developed later in life in female offspring. In male offspring, the risks of urogenital abnormalities and testicular cancer later in life are increased.

Neofollin has been assigned to pregnancy category X by the FDA. There are no controlled data in human pregnancy. Neofollin is contraindicated during pregnancy.

See references

Neofollin breastfeeding

When a drug is taken when the patient is breast feeding, a part of the drug is secreted in her breast milk and is passed to the baby. The dosage of the medicine to mother and baby are different, and many drugs actions are side effects when you take them without a disease, and what if you the baby takes them without a disease? What if the drug is contraindicated in newborns, infants or children? So, breastfeeding is a very alarming situation when the mother is on medications. Ask your Physician or Pediatrician about the effect of the drug on the baby and how much is excreted in breast milk and if it harms the baby!

Limited data are available on the excretion of Neofollin into human milk. The American Academy of Pediatrics considers Neofollin to be usually compatible with breast-feeding despite reports of "withdrawal" and "vaginal bleeding". Neofollin has been shown to decrease to quantity and quality of the milk. Estrogens are not indicated for the prevention of postpartum breast engorgement. The manufacturer recommends that caution be used when administering Neofollin to nursing women.

See references

References for pregnancy information

  1. Heinonen O, Slone D, Shapiro S; Kaufman DW ed. "Birth Defects and Drugs in Pregnancy." Littleton, MA: Publishing Sciences Group, Inc. (1977): 297
  2. "Product Information. Estrace (Neofollin)." Bristol-Myers Squibb, Princeton, NJ.

References for breastfeeding information

  1. "Product Information. Estrace (Neofollin)." Bristol-Myers Squibb, Princeton, NJ.
  2. Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50


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References

  1. DailyMed. "ESTRADIOL HEMIHYDRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Vivelle-Dot: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. Human Metabolome Database (HMDB). "Estradiol: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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