Neomycin Topical Uses

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What is Neomycin Topical?

Neomycin Topical belongs to the family of medicines called antibiotics. Neomycin Topical preparations are used to help prevent infections of the skin. Neomycin Topical may be used for other problems as determined by your doctor.

Neomycin Topical preparations are available without a prescription.

Neomycin Topical indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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eye infections, skin infections

How should I use Neomycin Topical?

Use Neomycin Topical as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Neomycin Topical.

Uses of Neomycin Topical in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Neomycin Topical is used topically to prevent or treat skin infections caused by bacteria.

Neomycin Topical description

A component of Neomycin Topical that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)

Neomycin Topical dosage

Neomycin Topical Dosage

Applies to the following strength(s): 125 mg/5 mL; 500 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

1 g orally every hour for 4 doses followed by 1 g every 4 hours for 5 doses

Alternate dosing: 6 g/day orally divided every 4 hours for 2 to 3 days

Usual Adult Dose for Hepatic Encephalopathy

4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days

Usual Adult Dose for Hepatic Coma

4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days

Usual Adult Dose for Diarrhea

3 g/day orally in 4 divided doses

Usual Pediatric Dose for Bowel Preparation

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

Less than 1 month: 50 mg/kg/day orally divided every 6 hours

1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours

Usual Pediatric Dose for Hepatic Encephalopathy

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days

Usual Pediatric Dose for Hepatic Coma

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days

Usual Pediatric Dose for Diarrhea

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

Less than 1 month: 50 mg/kg/day orally divided every 6 hours

1 year to 18 years: 50 mg/kg/day orally divided every 6 hours for 2 to 3 days

Renal Dose Adjustments

Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral Neomycin Topical. Use of a less nephrotoxic medication may be a consideration for this patient.

Liver Dose Adjustments

In chronic hepatic insufficiency, it may be necessary to give Neomycin Topical sulfate 4 g daily for an indefinite period, if less toxic drugs cannot be used.

Dose Adjustments

Caution should be used when administering Neomycin Topical to patients with renal impairment. Dose reduction should be considered in these patients.

Precautions

To minimize the risk of toxicity use the lowest possible dose and the shortest possible treatment period to control the condition. Treatment periods of longer than 2 weeks are not recommended.

Do not use in patients with intestinal obstruction.

Do not use in patients with inflammatory or ulcerative gastrointestinal disease due to the potential for increased gastrointestinal absorption of the drug.

Patients should be monitored for nephrotoxicity and ototoxicity.

Neomycin Topical should be used with caution in patients with hearing impairment, renal impairment or neuromuscular disorders.

Dialysis

Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral Neomycin Topical. Use of a less nephrotoxic medication may be a consideration for this patient.

More about Neomycin Topical

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Neomycin Topical interactions

See also:
What other drugs will affect Neomycin Topical?

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Caution should be taken in concurrent or serial use of other neurotoxic and/ or nephrotoxic drugs because of possible enhancement of the nephrotoxicity and/or ototoxicity of Neomycin Topical.

Caution should also be taken in concurrent or serial use of other aminoglycosides and polymyxins because they may enhance Neomycin Topicalís nephrotoxicity and/or ototoxicity and potentiate Neomycin Topical sulfateís neuromuscular blocking effects.

Oral Neomycin Topical inhibits the gastrointestinal absorption of penicillin V, oral vitamin B-12, methotrexate and 5-fluorouracil. The gastrointestinal absorption of digoxin also appears to be inhibited. Therefore, digoxin serum levels should be monitored.

Oral Neomycin Topical sulfate may enhance the effect of coumarin in anticoagulants by decreasing vitamin K availability.

Neomycin Topical side effects

See also:
What are the possible side effects of Neomycin Topical?

Applies to Neomycin Topical: topical cream, topical ointment

In addition to its needed effects, some unwanted effects may be caused by Neomycin Topical (the active ingredient contained in Neomycin Topical). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Neomycin Topical:

More common:

Rare

Neomycin Topical contraindications

See also:
What is the most important information I should know about Neomycin Topical?

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Neomycin Topical sulfate oral preparations are contraindicated in the presence of intestinal obstruction and in individuals with a history of hypersensitivity to the drug.

Patients with a history of hypersensitivity or serious toxic reaction to other aminoglycosides may have a cross-sensitivity to Neomycin Topical.

Neomycin Topical sulfate oral preparations are contraindicated in patients with inflammatory or ulcerative gastrointestinal disease because of the potential for enhanced gastrointestinal absorption of Neomycin Topical.

Active ingredient matches for Neomycin Topical:

Neomycin topical


List of Neomycin Topical substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Ointment; Topical; Neomycin Sulfate 0.5% (Pharmacia upjohn)
Neos NA Cream (Universal Twin Labs)$ 0.22
SOFRAMAX CREAM 1 tube / 15 GM cream each (Leeford Healthcare Ltd)$ 0.16
Sofraxine 5% w/w Cream (Universal Twin Labs)$ 0.28

References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "neomycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "neomycin". http://www.drugbank.ca/drugs/DB00452 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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