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Neomycin Topical Actions |
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Neomycin Topical belongs to the class of medications called as antibiotics. It prevents the bacterial growth by stopping the production of essential protein in the bacterial cells, thereby relieving the associated symptoms.
If you are using Neomycin Topical without a prescription, do not use it to treat deep wounds, puncture wounds, serious burns, or raw areas without first checking with your health care professional.
Do not use Neomycin Topical in the eyes.
Before applying Neomycin Topical, wash the affected area with soap and water, and dry thoroughly.
For patients using the cream form of Neomycin Topical:
For patients using the ointment form of Neomycin Topical:
After Neomycin Topical is applied, the treated area may be covered with a gauze dressing if desired.
To help clear up your infection completely, keep using Neomycin Topical for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.
The dose of Neomycin Topical will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Neomycin Topical. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of Neomycin Topical, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Never take Neomycin Topical in larger amounts than recommended, or for longer than 2 weeks. High doses or long-term use of Neomycin Topical can cause serious kidney problems, or hearing loss that may not be reversible. The longer you take Neomycin Topical, the more likely you are to develop these serious side effects. Follow the directions on your prescription label.
Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Neomycin Topical will not treat a viral infection such as the common cold or flu.
To be sure this medication is not causing harmful effects, your kidney function, and your nerve and muscle function will need to be tested often. You may also need hearing tests. Neomycin Topical can have long lasting effects on your body. Do not miss any follow up visits to your doctor for blood or urine tests.
If you are taking Neomycin Topical for hepatic coma, your treatment may also include a special diet. It is very important to follow the diet plan created for you by your doctor. You should become very familiar with the list of foods you should avoid to help control your condition.
If you need surgery, tell the surgeon ahead of time that you are using Neomycin Topical. Neomycin Topical can interact with certain medicines that may be given during surgery.
Store at room temperature away from moisture and heat. Do not allow the liquid form of this medicine to freeze.
Aminoglycosides like Neomycin Topical "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically Neomycin Topical binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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