Neomycin Topical Dosage

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Dosage of Neomycin Topical in details

The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Neomycin Topical Dosage

Applies to the following strength(s): 125 mg/5 mL; 500 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

1 g orally every hour for 4 doses followed by 1 g every 4 hours for 5 doses

Alternate dosing: 6 g/day orally divided every 4 hours for 2 to 3 days

Usual Adult Dose for Hepatic Encephalopathy

4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days

Usual Adult Dose for Hepatic Coma

4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days

Usual Adult Dose for Diarrhea

3 g/day orally in 4 divided doses

Usual Pediatric Dose for Bowel Preparation

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

Less than 1 month: 50 mg/kg/day orally divided every 6 hours

1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours

Usual Pediatric Dose for Hepatic Encephalopathy

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days

Usual Pediatric Dose for Hepatic Coma

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days

Usual Pediatric Dose for Diarrhea

The safety and efficacy of Neomycin Topical in children less than 18 years of age has not been established. However, the use of Neomycin Topical may be appropriate is some situations.

Less than 1 month: 50 mg/kg/day orally divided every 6 hours

1 year to 18 years: 50 mg/kg/day orally divided every 6 hours for 2 to 3 days

Renal Dose Adjustments

Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral Neomycin Topical. Use of a less nephrotoxic medication may be a consideration for this patient.

Liver Dose Adjustments

In chronic hepatic insufficiency, it may be necessary to give Neomycin Topical sulfate 4 g daily for an indefinite period, if less toxic drugs cannot be used.

Dose Adjustments

Caution should be used when administering Neomycin Topical to patients with renal impairment. Dose reduction should be considered in these patients.

Precautions

To minimize the risk of toxicity use the lowest possible dose and the shortest possible treatment period to control the condition. Treatment periods of longer than 2 weeks are not recommended.

Do not use in patients with intestinal obstruction.

Do not use in patients with inflammatory or ulcerative gastrointestinal disease due to the potential for increased gastrointestinal absorption of the drug.

Patients should be monitored for nephrotoxicity and ototoxicity.

Neomycin Topical should be used with caution in patients with hearing impairment, renal impairment or neuromuscular disorders.

Dialysis

Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral Neomycin Topical. Use of a less nephrotoxic medication may be a consideration for this patient.

More about Neomycin Topical

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What other drugs will affect Neomycin Topical?

Neomycin Topical can harm your kidneys, and this effect is increased when you also use certain other medicines harmful to the kidneys. Before using Neomycin Topical, tell your doctor about all other medicines you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.

Before you take Neomycin Topical, tell your doctor if you are using any other antibiotics, such as

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Neomycin Topical. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Neomycin Topical interactions

Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Neomycin Topical, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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Caution should be taken in concurrent or serial use of other neurotoxic and/ or nephrotoxic drugs because of possible enhancement of the nephrotoxicity and/or ototoxicity of Neomycin Topical.

Caution should also be taken in concurrent or serial use of other aminoglycosides and polymyxins because they may enhance Neomycin Topicalís nephrotoxicity and/or ototoxicity and potentiate Neomycin Topical sulfateís neuromuscular blocking effects.

Oral Neomycin Topical inhibits the gastrointestinal absorption of penicillin V, oral vitamin B-12, methotrexate and 5-fluorouracil. The gastrointestinal absorption of digoxin also appears to be inhibited. Therefore, digoxin serum levels should be monitored.

Oral Neomycin Topical sulfate may enhance the effect of coumarin in anticoagulants by decreasing vitamin K availability.

References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. FDA/SPL Indexing Data. "4BOC774388: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
  3. MeSH. "Anti-Bacterial Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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The results of a survey conducted on ndrugs.com for Neomycin Topical are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Neomycin Topical. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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