Nucid Gel Uses

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What is Nucid Gel?

Nucid Gel is used as a dietary supplement for individuals who are deficient in Nucid Gel. Although a balanced diet usually supplies all the Nucid Gel a person needs, Nucid Gel supplements may be needed by patients who have lost Nucid Gel because of illness or treatment with certain medicines.

Lack of Nucid Gel may lead to irritability, muscle weakness, and irregular heartbeat.

Injectable Nucid Gel is given only by or under the supervision of a health care professional. Some oral Nucid Gel preparations are available only with a prescription. Others are available without a prescription.

Nucid Gel indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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peptic ulcer, gastritis, dyspepsia

How should I use Nucid Gel?

Use Nucid Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Nucid Gel.

Uses of Nucid Gel in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

This medication is a mineral supplement used to prevent and treat low amounts of Nucid Gel in the blood. Nucid Gel is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of Nucid Gel. However, certain situations cause your body to lose Nucid Gel faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).

How to use Nucid Gel (oxide/AA chelate)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

It is best to take Nucid Gel supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.

Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.

Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much Nucid Gel in the blood can cause serious side effects.

Tell your doctor if symptoms of low Nucid Gel blood levels (e.g., muscle cramps, tiredness, irritability, depression) persist or worsen. If you think you may have a serious medical problem, seek immediate medical attention.

Nucid Gel dosage

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Usual Adult Dose for Hypomagnesemia

500 to 1000 mg Nucid Gel gluconate (27 to 54 mg elemental Nucid Gel) orally 3 times a day.

Usual Adult Dose for Dietary Supplement

500 to 1000 mg Nucid Gel gluconate (27 to 54 mg elemental Nucid Gel) orally once a day.

Usual Pediatric Dose for Hypomagnesemia

10 to 20 mg/kg of elemental Nucid Gel per dose orally 4 times a day. Use Nucid Gel gluconate oral liquid preparations for more accurate measurement of dose.

Renal Dose Adjustments

Do not use without physician supervision in patients with renal impairment due to increased risk of hypermagnesemia. The use of Nucid Gel salts are generally contraindicated in patients with severe renal dysfunction.

Liver Dose Adjustments

Data not available

Dose Adjustments

May increase by 500 to 1,000 mg/day (27 to 54 mg elemental Nucid Gel) in order to achieve a normal serum Nucid Gel level. Daily doses > 1,000 mg (54 mg elemental Nucid Gel) should be given in 2 to 3 divided doses.

Precautions

Because Nucid Gel is primarily eliminated by the kidney, there is significant risk of hypermagnesemia in patients with renal dysfunction.

Dialysis

Data not available; however, use of Nucid Gel salts is generally contraindicated in renal failure.

Other Comments

Nucid Gel supplements are often used with "low normal" serum Nucid Gel levels in patients predisposed to hypomagnesemia (e.g., patients on diuretics).

Nucid Gel interactions

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What other drugs will affect Nucid Gel?

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Alfacalcidol: May increase the serum concentration of Nucid Gel Salts. Consider therapy modification

Alpha-Lipoic Acid: Nucid Gel Salts may decrease the absorption of Alpha-Lipoic Acid. Alpha-Lipoic Acid may decrease the absorption of Nucid Gel Salts. Consider therapy modification

Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination

Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification

Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification

Calcitriol (Systemic): May increase the serum concentration of Nucid Gel Salts. Management: Consider using a non-Nucid Gel-containing antacid or phosphate-binding product in patients also receiving calcitriol. If Nucid Gel-containing products must be used with calcitriol, serum Nucid Gel concentrations should be monitored closely. Consider therapy modification

Calcium Channel Blockers: May enhance the adverse/toxic effect of Nucid Gel Salts. Nucid Gel Salts may enhance the hypotensive effect of Calcium Channel Blockers. Monitor therapy

Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification

Dolutegravir: Nucid Gel Salts may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Nucid Gel salts. Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Nucid Gel salts. Consider therapy modification

Doxercalciferol: May enhance the hypermagnesemic effect of Nucid Gel Salts. Management: Consider using a non-Nucid Gel-containing antacid or phosphate-binding product in patients also receiving doxercalciferol. If Nucid Gel-containing products must be used with doxercalciferol, serum Nucid Gel concentrations should be monitored closely. Consider therapy modification

Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification

Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification

Gabapentin: Nucid Gel Salts may enhance the CNS depressant effect of Gabapentin. Specifically, high dose intravenous/epidural Nucid Gel sulfate may enhance the CNS depressant effects of gabapentin. Nucid Gel Salts may decrease the serum concentration of Gabapentin. Management: Administer gabapentin at least 2 hours after use of a Nucid Gel-containing antacid. Monitor patients closely for evidence of reduced response to gabapentin therapy. Monitor for CNS depression if high dose IV/epidural Nucid Gel sulfate is used. Consider therapy modification

Levothyroxine: Nucid Gel Salts may decrease the serum concentration of Levothyroxine. Management: Separate administration of oral levothyroxine and oral Nucid Gel salts by at least 4 hours. Consider therapy modification

Multivitamins/Fluoride (with ADE): Nucid Gel Salts may decrease the serum concentration of Multivitamins/Fluoride (with ADE). Specifically, Nucid Gel salts may decrease fluoride absorption. Management: To avoid this potential interaction separate the administration of Nucid Gel salts from administration of a fluoride-containing product by at least 1 hour. Consider therapy modification

Mycophenolate: Nucid Gel Salts may decrease the serum concentration of Mycophenolate. Management: Separate doses of mycophenolate and oral Nucid Gel salts. Monitor for reduced effects of mycophenolate if taken concomitant with oral Nucid Gel salts. Consider therapy modification

Neuromuscular-Blocking Agents: Nucid Gel Salts may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Monitor therapy

PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification

Phosphate Supplements: Nucid Gel Salts may decrease the serum concentration of Phosphate Supplements. Management: Administer oral phosphate supplements as far apart from the administration of an oral Nucid Gel salt as possible to minimize the significance of this interaction. Exceptions: Sodium Glycerophosphate Pentahydrate. Consider therapy modification

Quinolones: Nucid Gel Salts may decrease the serum concentration of Quinolones. Management: Administer oral quinolones several hours before (4 h for moxi/pe/spar-, 2 h for others) or after (8 h for moxi-, 6 h for cipro/dela-, 4 h for lome/pe-, 3 h for gemi-, and 2 h for levo-, nor-, or ofloxacin or nalidixic acid) oral Nucid Gel salts. Exceptions: LevoFLOXacin (Oral Inhalation). Consider therapy modification

Raltegravir: Nucid Gel Salts may decrease the serum concentration of Raltegravir. Management: Avoid the use of oral / enteral Nucid Gel salts with raltegravir. No dose separation schedule has been established that adequately reduces the magnitude of interaction. Avoid combination

Tetracyclines: Nucid Gel Salts may decrease the absorption of Tetracyclines. Only applicable to oral preparations of each agent. Management: Avoid coadministration of oral Nucid Gel salts and oral tetracyclines. If coadministration cannot be avoided, administer oral Nucid Gel at least 2 hours before, or 4 hours after, oral tetracyclines. Monitor for decreased tetracycline therapeutic effects. Exceptions: Eravacycline. Consider therapy modification

Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification

Nucid Gel side effects

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What are the possible side effects of Nucid Gel?

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Diarrhoea and bowel discomfort, due to the release of carbon dioxide caused by both Nucid Gel carbonate and sodium bicarbonate.

Excessive administration of Nucid Gel leads to the development of hypermagnesaemia, especially in renal insufficiency. Symptoms of hypermagnesaemia may include flushing of the skin, thirst, hypotension due to peripheral vasodilation, drowsiness, confusion, loss of tendon reflexes due to neuromuscular blockade, muscle weakness, respiratory depression, cardiac arrhythmias, coma, and cardiac arrest. Nucid Gel carbonate and Nucid Gel trisilicate may interfere with the absorption of other medicines when taken concomitantly. Administration of sodium bicarbonate by mouth can cause stomach cramps and flatulence.

Excessive administration of sodium bicarbonate may lead to metabolic alkalosis, especially in patients with impaired renal function. Symptoms may include shortness of breath, muscle weakness (associated with potassium depletion), and mental disturbances such as restlessness, convulsions, and coma. Muscle hypertonicity, twitching, and tetany may develop especially in hypocalcaemic patients due to increased protein binding and renal reabsorption of calcium. Excessive doses may also lead to sodium overloading and hyperosmolality. Sodium excess may result in hypernatraemia, a rise in extracellular concentration or in too much sodium and water in the body without change in extracellular concentration.

Retention of sodium leads to the accumulation of extracellular fluid (oedema) which may affect the cerebral, pulmonary or peripheral circulations.

Nucid Gel contraindications

See also:
What is the most important information I should know about Nucid Gel?

Sensitivity to any of the ingredients; patients with renal impairment and acute dehydration.

Active ingredient matches for Nucid Gel:

Magnesium Hydroxide (Milk of Magnesia)


Unit description / dosage (Manufacturer)Price, USD
Nucid Gel 170 ml Nuclear Pharma Syrup$ 0.02
Nucid Gel 170 ml Suspension$ 0.00

List of Nucid Gel substitutes (brand and generic names):

Gastrin Tablet (Medi Rose)$ 0.00
Gastromax O 170 ml Suspension (Elder Pharmaceuticals Ltd.)$ 0.03
Gelpec MPS 170 ml Gel (Modern Pharmaceuticals)$ 0.02
Geltec Gel 170 ml Syrup (Dutech Remedies (I) Pvt. Ltd.)$ 0.04
Gelucaine 170 ml Suspension (The Pharmed Research Lab Pvt Ltd)$ 0.03
Gigel 170 ml Gel (Prayas Pharmaceuticals)$ 0.01
HC Gel 200 ml Gel (Health Care Formulations Pvt. Ltd.)$ 0.02
HC Gel 100 ml Gel (Health Care Formulations Pvt. Ltd.)$ 0.02
HC REX 200 ml Gel (Health Care Formulations Pvt. Ltd.)$ 0.02
Hegel MPS Syrup (Health Guard (India) Pvt. Ltd.)$ 0.02
Hydralgel MPS 250+250+50 Tablet (Adcco Limited.)$ 0.01
Icycool 200 ml Syrup (Injecto Capta Pvt. Ltd.)$ 0.02
Inlicid MPS 170 ml Suspension (Indian Drugs and Pharmaceuticals Ltd (Ind Biosciences))$ 0.02
Intacid MPS 170 ml Syrup (Intas Laboratories Pvt Ltd)$ 0.05
Intacid MPS 60 ml Syrup (Intas Laboratories Pvt Ltd)$ 0.06
Intacid MPS Tablet (Intas Laboratories Pvt Ltd)$ 0.01
Neutrogel 170 ml Suspension (Beckcem Drugs International (P) Ltd)$ 0.02
Nokcid MPS 170 ml Syrup (Ambition Pharma Pvt. Ltd.)$ 0.02
Nomorcid MPS 170 ml Suspension (Acto Pharmaceuticals Laboratories)$ 0.02
Normacid 170 ml Gel (Saga Laboratories)$ 0.04
Oltacal Tablet (Altar Healthcare (P) Ltd.)$ 0.04
Orcid 170 ml Suspension (Oirpil Biotech)$ 0.02
Oxecain Gel 200 ml Suspension (Saksham Pharmaceuticals (India) Limited)$ 0.03
Oxycane 170 ml Gel (Invision Medi Sciences)$ 0.05
Sanzyme DS Tablet (Uni-Sankyo Ltd.)$ 0.01
Silocid MPS 170 ml Suspension (Suzikem Drugs Pvt. Ltd.)$ 0.02
Simeco Gel 200 ml Gel (Wyeth Ltd.)$ 0.01
Stgel Mint 170 ml Suspension (ST Sharda Lifesciences)$ 0.06
Stomacid MPS 170 ml Syrup (Pramukh Swami Pharma Ltd.)$ 0.02
Sugel 200 ml Syrup (Winsun Laboratories)$ 0.05
Synogel 100 ml Gel (Synokem Pharmaceuticals Ltd)$ 0.03
Ticid 200 ml Suspension (Tunic Healthcare)$ 0.01
Tisbi 170 ml Syrup (Proteger India)$ 0.04
UD Alusil 200+300+25 Tablet (Union Drug Company Ltd)$ 0.00
Ulcid Tablet (Acron Pharmaceuticals)$ 0.01
Veecain 170 ml Syrup (Vsaar Pharma)$ 0.03
Visco Tablet (Aristo Pharmaceuticals Pvt Ltd.)$ 0.01
VISCO TABLET 1 strip / 10 tablets each (Aristo Pharmaceuticals Pvt Ltd.)$ 0.10
Zancid 170 ml Suspension (Jarson Pharmaceuticals)$ 0.02
Zocid Gel 170 ml Gel (Zota Healthcare Pvt. Ltd.)$ 0.02

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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