Obenix Uses

How do you administer this medicine?
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What is Obenix?

Obenix (Obenix) is a stimulant similar to an amphetamine. Obenix is an appetite suppressant that affects the central nervous system.

Obenix is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Obenix may also be used for purposes not listed in this medication guide.

Obenix indications

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Obenix™ tablets are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity in patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).

Below is a chart of body mass index (BMI) based on various heights and weights.

BMI is calculated by taking the patient’s weight, in kilograms (kg), divided by the patient’s height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches x 0.0254 = meters.

BODY MASS INDEX (BMI), kg/m2

The limited usefulness of agents of this class, including Obenix, should be measured against possible risk factors inherent in their use such as those described below.

How should I use Obenix?

Use Obenix orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Obenix orally disintegrating tablets.

Uses of Obenix in details

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Obenix is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

It is not known how this medication helps people to lose weight. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.

How to use Obenix

Take this medication by mouth as directed by your doctor, usually once a day, 1 hour before breakfast or 1 to 2 hours after breakfast. If needed, your doctor may adjust your dose to take a small dose up to 3 times a day. Carefully follow your doctor's instructions. Taking this medication late in the day may cause trouble sleeping (insomnia).

If you are using sustained-release capsules, the dose is usually taken once a day before breakfast or at least 10 to 14 hours before bedtime. Swallow the medication whole. Do not crush or chew sustained-release capsules. Doing so can release all of the drug at once, increasing the risk of side effects.

If you are using the tablets made to dissolve in the mouth, the dose is usually taken once a day in the morning, with or without food. First, dry your hands before handling the tablet. Place your dose on top of the tongue until it dissolves, then swallow it with or without water.

The dosage is based on your medical condition and response to therapy. Your doctor will adjust the dose to find the best dose for you. Use this medication regularly and exactly as prescribed in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.

This medication is usually taken for only a few weeks at a time. It should not be taken with other appetite suppressants. The possibility of serious side effects increases with longer use of this medication and use of this drug along with certain other diet drugs.

This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as depression, severe tiredness) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.

Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.

This medication may stop working well after you have been taking it for a few weeks. Talk with your doctor if this medication stops working well. Do not increase the dose unless directed by your doctor. Your doctor may direct you to stop taking this medication.

Obenix description

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A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. [PubChem]. Some common brand names for Obenix are Obenix® and Obenix™. Obenix is also available in combination medications such as Qsymia®.

Obenix dosage

Obenix Dosage

Generic name: Obenix HYDROCHLORIDE 37.5mg

Dosage form: tablet, orally disintegrating

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Exogenous Obesity

Dosage should be individualized to obtain an adequate response with the lowest effective dose.

The usual adult dose is one tablet as prescribed by the physician, administered in the morning, with or without food. Obenix is not recommended for use in pediatric patients less than or equal to 16 years of age.

Late evening medication should be avoided because of the possibility of resulting insomnia.

With dry hands, gently remove the Obenix (Obenix hydrochloride ODT) tablet from the bottle. Immediately place the Obenix tablet on top of the tongue where it will dissolve, then swallow with or without water.

More about Obenix (Obenix)

Consumer resources

Professional resources

Related treatment guides

Obenix interactions

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What other drugs will affect Obenix?

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Monoamine Oxidase Inhibitors

Use of Obenix is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis.

Alcohol

Concomitant use of alcohol with Obenix may result in an adverse drug reaction.

Insulin and

Oral Hypoglycemic Medications

Requirements may be altered.

Adrenergic Neuron Blocking Drugs

Obenix may decrease the hypotensive effect of adrenergic neuron blocking drugs.

Drug Abuse And Dependence

Controlled Substance

Obenix is a Schedule IV controlled substance.

Abuse

Obenix is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Obenix should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.

Dependence

Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.

Obenix side effects

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What are the possible side effects of Obenix?

Applies to Obenix: oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating

As well as its needed effects, Obenix (the active ingredient contained in Obenix) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Obenix, check with your doctor immediately:

Rare

Incidence not known:

Minor Side Effects

Some Obenix side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

Obenix contraindications

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What is the most important information I should know about Obenix?

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Obenix if you are pregnant.

Do not use Obenix if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Taking Obenix together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take Obenix with any other diet medications without your doctor's advice.

Obenix may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase certain side effects of Obenix.

Obenix is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Obenix may be habit-forming and should be used only by the person it was prescribed for. Never share Obenix with another person, especially someone with a history of drug abuse or addiction. Keep track of the amount of medicine used from each new bottle. Obenix is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Do not stop using Obenix suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Obenix.



Active ingredient matches for Obenix:

Phentermine


List of Obenix substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
Capsule; Oral; Phentermine Hydrochloride 30 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg
Capsule; Oral; Phentermine Hydrochloride 30 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg
Capsule; Oral; Phentermine Hydrochloride 30 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg
Capsule; Oral; Phentermine Hydrochloride 30 mg
Tablet; Oral; Phentermine Hydrochloride 8 mg
Capsules; Oral; Phentermine Hydrochloride 30 mg
Tablets; Oral; Phentermine Hydrochloride 8 mg
Panbesy 15 mg x 200's (Eurodrug)
Panbesy 30 mg x 200's (Eurodrug)
Capsules; Oral; Phentermine Hydrochloride 15 mg (Eurodrug)
Capsules; Oral; Phentermine Hydrochloride 30 mg (Eurodrug)
Panbesy cap 15 mg 200's (Eurodrug)
Panbesy cap 30 mg 200's (Eurodrug)
Panbesy nyscap 15 mg 200's (Eurodrug)
Panbesy nyscap 30 mg 200's (Eurodrug)

References

  1. PubChem. "phentermine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "phentermine". http://www.drugbank.ca/drugs/DB00191 (accessed September 17, 2018).
  3. DTP/NCI. "phentermine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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