What happens if I overdose Oligogranul Magnesium?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; dizziness; flushing; loss of consciousness; muscle weakness; severe drowsiness; slow heartbeat.
Proper storage of Oligogranul Magnesium:
Store Oligogranul Magnesium at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Oligogranul Magnesium out of the reach of children and away from pets.
Overdose of Oligogranul Magnesium in details
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include slow heartbeat, severe drowsiness, dizziness, confusion, muscle weakness, loss of consciousness.
Notes
Keep all regular medical and laboratory appointments. If your doctor has directed you to take this medication, laboratory and/or medical tests (e.g., Oligogranul Magnesium blood levels, kidney function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
Oligogranul Magnesium supplements are available in different forms with different amounts of Oligogranul Magnesium. Many are available without a prescription. Ask your doctor or pharmacist for help in selecting the best product for you.
Eat a well-balanced diet. Foods high in Oligogranul Magnesium include avocados, bananas, beans, whole grain cereals, green vegetables, and nuts.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage
Store at room temperature away from light and moisture. Refer to the product package for details. Do not store in the bathroom. If you have any questions about storage, ask your pharmacist. Keep all drug products away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
What should I avoid while taking Oligogranul Magnesium?
There are no restrictions on food, beverages, or activity while using Oligogranul Magnesium gluconate unless your doctor has told you otherwise.
Oligogranul Magnesium warnings
Oligogranul Magnesium lactate should be taken with food to lessen the chance of diarrhea. Do not take any other vitamin or mineral supplements that contain Oligogranul Magnesium unless your doctor has told you to.
There may be other drugs that can interact with Oligogranul Magnesium lactate. Tell your doctor about all other medications you use, especially sodium polystyrene sulfonate (Kayexalate, Kionex), or a tetracycline antibiotic.
Get emergency medical help if you think you have used too much medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take Oligogranul Magnesium lactate, tell your doctor if you have:
kidney disease; or
heart disease.
FDA pregnancy category C. It is not known whether Oligogranul Magnesium lactate is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Oligogranul Magnesium lactate may pass into breast milk. Although it is not expected to cause harm to a nursing baby, do not use Oligogranul Magnesium lactate without telling your doctor if you are breast-feeding a baby.
Do not take any other vitamin or mineral supplements that contain Oligogranul Magnesium unless your doctor has told you to.
What should I discuss with my healthcare provider before taking Oligogranul Magnesium?
Some medical conditions may interact with Oligogranul Magnesium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have appendicitis, diarrhea, a blockage of your intestines, heart problems, or kidney problems
Some MEDICINES MAY INTERACT with Oligogranul Magnesium. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Oligogranul Magnesium
- Bisphosphonates (eg, risedronate), digoxin, penicillamine, quinolone antibiotics (eg, ciprofloxacin), or tetracyclines (eg, doxycycline) because their effectiveness may be decreased by Oligogranul Magnesium
This may not be a complete list of all interactions that may occur. Ask your health care provider if Oligogranul Magnesium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Oligogranul Magnesium precautions
General
Administer with caution if flushing and sweating occurs. When barbiturates, narcotics or other hypnotics (or systemic anesthetics) are to be given in conjunction with Oligogranul Magnesium, their dosage should be adjusted with caution because of additive CNS depressant effects of Oligogranul Magnesium.
Because Oligogranul Magnesium is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. Urine output should be maintained at a level of 100 mL or more during the four hours preceding each dose. Monitoring serum Oligogranul Magnesium levels and the patient’s clinical status is essential to avoid the consequences of overdosage in toxemia. Clinical indications of a safe dosage regimen include the presence of the patellar reflex (knee jerk) and absence of respiratory depression (approximately 16 breaths or more/minute). When repeated doses of the drug are given parenterally, knee jerk reflexes should be tested before each dose and if they are absent, no additional Oligogranul Magnesium should be given until they return. Serum Oligogranul Magnesium levels usually sufficient to control convulsions range from 3 to 6 mg/100 mL (2.5 to 5 mEq/liter). The strength of the deep tendon reflexes begins to diminish when Oligogranul Magnesium levels exceed 4 mEq/liter. Reflexes may be absent at 10 mEq Oligogranul Magnesium/liter, where respiratory paralysis is a potential hazard. An injectable calcium salt should be immediately available to counteract the potential hazards of Oligogranul Magnesium intoxication in eclampsia.
50% Oligogranul Magnesium Sulfate Injection, USP must be diluted to a concentration of 20% or less prior to intravenous infusion. Rate of administration should be slow and cautious, to avoid producing hypermagnesemia. The 50% solution also should be diluted to 20% or less for intramuscular injection in infants and children.
Laboratory Tests
Oligogranul Magnesium sulfate injection should not be given unless hypomagnesemia has been confirmed and the serum concentration of Oligogranul Magnesium is monitored. The normal serum level is 1.5 to 2.5 mEq/L.
Drug Interactions
CNS Depressants — When barbiturates, narcotics or other hypnotics (or systemic anesthetics), or other CNS depressants are to be given in conjunction with Oligogranul Magnesium, their dosage should be adjusted with caution because of additive CNS depressant effects of Oligogranul Magnesium. CNS depression and peripheral transmission defects produced by Oligogranul Magnesium may be antagonized by calcium.
Neuromuscular Blocking Agents — Excessive neuromuscular block has occurred in patients receiving parenteral Oligogranul Magnesium sulfate and a neuromuscular blocking agent; these drugs should be administered concomitantly with caution.
Cardiac Glycosides — Oligogranul Magnesium sulfate should be administered with extreme caution in digitalized patients, because serious changes in cardiac conduction which can result in heart block may occur if administration of calcium is required to treat Oligogranul Magnesium toxicity.
Pregnancy
Teratogenic Effects
Pregnancy Category D
See WARNINGS and PRECAUTIONS.
Oligogranul Magnesium sulfate can cause fetal abnormalities when administered beyond 5 to 7 days to pregnant women. There are retrospective epidemiological studies and case reports documenting fetal abnormalities such as hypocalcemia, skeletal demineralization, osteopenia and other skeletal abnormalities with continuous maternal administration of Oligogranul Magnesium sulfate for more than 5 to 7 days.1-10 Oligogranul Magnesium sulfate injection should be used during pregnancy only if clearly needed. If this drug is used during pregnancy, the woman should be apprised of the potential harm to the fetus.
Nonteratogenic Effects
When administered by continuous intravenous infusion (especially for more than 24 hours preceding delivery) to control convulsions in a toxemic woman, the newborn may show signs of Oligogranul Magnesium toxicity, including neuromuscular or respiratory depression.
Labor and Delivery
Continuous administration of Oligogranul Magnesium sulfate is an unapproved treatment for preterm labor. The safety and efficacy of such use have not been established. The administration of Oligogranul Magnesium sulfate outside of its approved indication in pregnant women should be by trained obstetrical personnel in a hospital setting with appropriate obstetrical care facilities.
Nursing Mothers
Since Oligogranul Magnesium is distributed into milk during parenteral Oligogranul Magnesium sulfate administration, the drug should be used with caution in nursing women.
Geriatrics
Geriatric patients often require reduced dosage because of impaired renal function. In patients with severe impairment, dosage should not exceed 20 grams in 48 hours. Serum Oligogranul Magnesium should be monitored in such patients.
What happens if I miss a dose of Oligogranul Magnesium?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
