Ornidone Fort Uses

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Ornidone Fort indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Amoebiasis

Adult: 0.5 g bid for 5-10 days.

Child: 25 mg/kg as a single daily dose for 5-10 days.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Amoebic dysentery

Adult: 1.5 g as a single daily dose for 3 days. Alternatively for patients >60 kg: 1 g bid for 3 days.

Child: 40 mg/kg daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Giardiasis

Adult: 1-1.5 g as a single daily dose for 1-2 days.

Child: 30-40 mg/kg daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Trichomoniasis

Adult: 1.5 g as a single daily dose or 0.5 g bid for 5 days. Treat sexual partners concomitantly.

Child: 25 mg/kg as a single dose.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Intravenous

Severe amoebic dysentery; Amoebic liver abscess

Adult: Initially, 0.5-1 g infusion followed by 0.5 g every 12 hrs for 3-6 days.

Child: 20-30 mg/kg body wt daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Intravenous

Anaerobic bacterial infections

Adult: Initially, 0.5-1 g followed by 1 g daily as a single dose or in 2 divided doses for 5-10 days. Doses to be given via infusion. Substitute with 500 mg every 12 hr orally as soon as possible.

Child: 10 mg/kg every 12 hr for 5-10 days.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Intravenous

Prophylaxis of postoperative anaerobic bacterial infections

Adult: 1 g by IV about 30 minutes before surgery.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Uses of Ornidone Fort in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Ornidone Fort is used in the treatment of infections of vagina, urinary tract, intestine and other parts of the body caused by anaerobic bacteria (bacteria that do not use oxygen) or protozoa (amoeba or single-celled parasites). It is also used to prevent these infections during surgical procedures.

Ornidone Fort description

Ornidone Fort blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence has shown that bretylium may also inhibit the Na,K-ATPase by binding to the extracellular K-site.

Ornidone Fort dosage

Oral

Amoebiasis

Adult: 0.5 g bid for 5-10 days.

Child: 25 mg/kg as a single daily dose for 5-10 days.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Amoebic dysentery

Adult: 1.5 g as a single daily dose for 3 days. Alternatively for patients >60 kg: 1 g bid for 3 days.

Child: 40 mg/kg daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Giardiasis

Adult: 1-1.5 g as a single daily dose for 1-2 days.

Child: 30-40 mg/kg daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Oral

Trichomoniasis

Adult: 1.5 g as a single daily dose or 0.5 g bid for 5 days. Treat sexual partners concomitantly.

Child: 25 mg/kg as a single dose.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Intravenous

Severe amoebic dysentery; Amoebic liver abscess

Adult: Initially, 0.5-1 g infusion followed by 0.5 g every 12 hrs for 3-6 days.

Child: 20-30 mg/kg body wt daily.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Intravenous

Anaerobic bacterial infections

Adult: Initially, 0.5-1 g followed by 1 g daily as a single dose or in 2 divided doses for 5-10 days. Doses to be given via infusion. Substitute with 500 mg every 12 hr orally as soon as possible.

Child: 10 mg/kg every 12 hr for 5-10 days.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Intravenous

Prophylaxis of postoperative anaerobic bacterial infections

Adult: 1 g by IV about 30 minutes before surgery.

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Hepatic impairment: Severe: Double the interval between doses.

Reconstitution: Dilute to a concentration of ≤5 mg/ml.

Ornidone Fort interactions

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Digitalis toxicity may be aggravated by the initial release of norepinephrine caused by Ornidone Fort Tosylate Injection.

The pressor effects of catecholamines such as dopamine or norepinephrine are enhanced by Ornidone Fort Tosylate. When catecholamines are administered, dilute solutions should be used and blood pressure should be monitored closely.

Although there is little published information on concomitant administration of lidocaine and Ornidone Fort Tosylate, these drugs are often administered concurrently without any evidence of interactions resulting in adverse effects or diminished efficacy.

Ornidone Fort side effects

Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity, poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness and signs of sensory or mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.

Ornidone Fort contraindications

Hypersensitivity to Ornidone Fort or to other nitroimidazole derivatives.

Active ingredient matches for Ornidone Fort:

Ornidazole in Turkey.


List of Ornidone Fort substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
ORNIGYL IV 500MG INFUSION 1 bottle / 100 ML infusion each (JB Chemicals)$ 0.56
Ornikem 500 mg Tablet (Swisskem Healthcare)$ 0.07
Ornilet 500mg TAB / 10x10 (Avyukt)$ 7.60
ORNILET tab 500 mg x 10's (Avyukt)$ 0.76
500 mg x 10's (Obsurge Biotech Limited)$ 0.82
Ornimax 500 mg Tablet (Obsurge Biotech Limited)$ 0.08
Ornimax 500mg FC-TAB / 10 (Obsurge Biotech Limited)$ 0.82
ORNIMAX 500MG TABLET 1 strip / 10 tablets each (Obsurge Biotech Limited)$ 0.89
ORNIMAX film-coated tab 500 mg x 10's (Obsurge Biotech Limited)$ 0.82
Ornimax 500mg FC-TAB / 10 (Obsurge Biotech Limited)$ 0.82
Ornimax 500mg Tablet (Obsurge Biotech Limited)$ 0.09
Tablet, Film-Coated; Oral; Ornidazole 500 mg
Tablet; Vaginal; Ornidazole 500 mg
ORNIPIDI INFUSION 1 bottle / 100 ML infusion each (Parenteral Drugs India Ltd)$ 0.49
Tablet, Film-Coated; Oral; Ornidazole 250 mg (Abdi)
Tablet, Film-Coated; Oral; Ornidazole 500 mg (Abdi)
Tablet; Vaginal; Ornidazole 500 mg (Abdi)
ORNISTOP SUSPENSION 1 bottle / 50 ML suspension each (Delvin Formulations Pvt Ltd)$ 1.19
500 mg x 100's (East African (I) Remedies Pvt Ltd)$ 7.94
Ornivir 500 mg Tablet (East African (I) Remedies Pvt Ltd)$ 0.08
Ornivir 500mg TAB / 100 (East African (I) Remedies Pvt Ltd)$ 7.94
ORNIVIR tab 500 mg x 10's (East African (I) Remedies Pvt Ltd)$ 0.79
Ornivir 500mg TAB / 100 (East African (I) Remedies Pvt Ltd)$ 7.94
Orniz 500 mg Tablet (Udik Pharmaceuticals Pvt. Ltd.)$ 0.07
ORNIZEN Capsule/ Tablet / 500mg / 10 units (Sun Pharmaceutical Industries Ltd.)$ 0.72
Ornizen 500mg TAB / 10 (Sun Pharmaceutical Industries Ltd.)$ 0.72
500 mg x 10's (Sun Pharmaceutical Industries Ltd.)$ 0.72
Ornizen 500 mg Tablet (Sun Pharmaceutical Industries Ltd.)$ 0.07
ORNIZEN 500MG TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.)$ 0.77
ORNIZEN tab 500 mg x 10's (Sun Pharmaceutical Industries Ltd.)$ 0.72
Ornizen 500mg TAB / 10 (Sun Pharmaceutical Industries Ltd.)$ 0.72
Ornizen 500mg Tablet (Sun Pharmaceutical Industries Ltd.)$ 0.08

References

  1. PubChem. "Ornidazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Ornidazole". http://www.drugbank.ca/drugs/DB13026 (accessed September 17, 2018).
  3. DTP/NCI. "Ornidazole: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Ornidone Fort are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Ornidone Fort. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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