Osteomed Uses

How old is patient?

What is Osteomed?

Osteomed (alendronate) belongs to a group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures.

Osteomed effervescent tablet are used in women to treat or prevent osteoporosis that is caused by menopause.

Osteomed is also used to increase bone mass in men who have osteoporosis.

Osteomed indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Treatment of Osteoporosis in Postmenopausal Women

Osteomed effervescent tablet 70 mg is indicated for the treatment of osteoporosis in postmenopausal women. For the treatment of osteoporosis, alendronate sodium increases bone mass and reduces the incidence of fractures, including those of the hip and spine (vertebral compression fractures).

Treatment to Increase Bone Mass in Men With Osteoporosis

Osteomed is indicated for treatment to increase bone mass in men with osteoporosis.

Important Limitations of Use

The optimal duration of use has not been determined. The safety and effectiveness of Osteomed for the treatment of osteoporosis are based on clinical data of four years duration. All patients on bisphosphonate therapy should have the need for continued therapy re-evaluated on a periodic basis. Patients at low-risk for fracture should be considered for drug discontinuation after 3 to 5 years of use. Patients who discontinue therapy should have their risk for fracture re-evaluated periodically.

Uses of Osteomed in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Prevention and treatment of post-menopausal osteoporosis in women.

Osteomed may be used in some cancers and diseases to slow down the activity of osteoclasts, the cells that break down bone. Increased activity of these cells increases the levels of calcium in the blood. Paget’s disease of the bone.

Osteomed description

Osteomed (alendronate) is a nitrogen-containing, second generation bisphosphonate. Bisphosphonates were first used to treat Paget’s disease in 1971. This class of medications is comprised of inorganic pyrophosphate analogues that contain non-hydrolyzable P-C-P bonds. Similar to other bisphosphonates, alendronate has a high affinity for bone mineral and is taken up during osteoclast resorption. Alendronate inhibits farnesyl pyrophosphate synthetase, one of the enzymes in the mevalonic acid pathway involved in producing isoprenoid compounds that are essential for post-translational modification of small guanosine triphosphate (GTP)-binding proteins, such as Rho, Ras and Rab. Inhibition of this process interferes with osteoclast function and survival. Alendronate is used for the treatment of osteoporosis and Paget’s disease.

Osteomed dosage


Treatment Of Osteoporosis In Postmenopausal Women

The recommended dosage is one 70 mg effervescent tablet once weekly.

Treatment To Increase Bone Mass In Men With Osteoporosis

The recommended dosage is one 70 mg effervescent tablet once weekly.

Important Administration Instructions

Instruct patients to do the following to assure adequate drug absorption and to decrease the risk of esophageal adverse reactions: Waiting less than 30 minutes, or taking Osteomed with food, beverages (other than plain water) or other medications will lessen the effect of Osteomed by decreasing its absorption into the body.

  • Take Osteomed upon arising for the day and at least 30 minutes before the first food, beverage, or medication of the day.
  • Dissolve the effervescent tablet in 4 ounces room temperature plain water only (not mineral water or flavored water).
  • Wait at least 5 minutes after the effervescence stops and then stir the solution for approximately 10 seconds and ingest.
  • Avoid lying down for at least 30 minutes after taking Osteomed and until after their first food of the day.
  • Do not take Osteomed at bedtime or before arising for the day.
  • Failure to follow these instructions may increase the risk of esophageal adverse reactions.

Recommendations For Calcium And Vitamin D Supplementation

Instruct patients to take supplemental calcium and vitamin D if dietary intake is inadequate. Patients at increased risk for vitamin D insufficiency (e.g., over the age of 70 years, nursing home-bound, or chronically ill) may need vitamin D supplementation. Patients with gastrointestinal malabsorption syndromes may require higher doses of vitamin D supplementation and measurement of 25-hydroxyvitamin D should be considered.

Administration Instructions For Missed Doses

If the once-weekly dose is missed, instruct patients to take one dose on the morning after they remember. They should not take 2 doses on the same day but should return to taking one dose once a week, as originally scheduled on their chosen day.

How supplied

Dosage Forms And Strengths

Osteomed effervescent tablets are round, flat-faced, white to off-white tablets, 25 mm in diameter, with beveled edges, with “M” debossed on one side, containing 91.37 mg of alendronate sodium, which is equivalent to 70 mg of free Osteomed.

Storage And Handling

Osteomed effervescent tablets are round, flat faced, white to off-white tablets with beveled edges and “M” debossed on one side. Osteomed effervescent tablets, 70 mg are provided in blisters made of aluminum foil composite, as follows:

NDC 0178-0101-02 carton containing 4 units of use blisters

NDC 0178-0101-03 carton containing 12 units of use blisters

Store at 20°C to 25°C (68°F to 77°F), excursions permitted to 15°C to 30°C (59°F to 86°F), Protect from moisture. Store tablets in original blister package until use.

Manufactured for: Mission Pharmacal Company San Antonio, TX 78230 1355. Issued: February 2015

Osteomed interactions

See also:
What other drugs will affect Osteomed?


Calcium Supplements/Antacids

Co-administration of Osteomed and calcium, antacids, or oral medications containing multivalent cations will interfere with absorption of Osteomed. Therefore, instruct patients to wait at least one-half hour after taking Osteomed before taking any other oral medications.


In clinical studies, the incidence of upper gastrointestinal adverse events was increased in patients receiving concomitant therapy with daily doses of alendronate sodium greater than 10 mg and aspirin-containing products.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Osteomed may be administered to patients taking NSAIDs. In a 3-year, controlled, clinical study (n=2027) during which a majority of patients received concomitant NSAIDs, the incidence of upper gastrointestinal adverse events was similar in patients taking alendronate sodium 5 or 10 mg/day compared to those taking placebo. However, since NSAID use is associated with gastrointestinal irritation, caution should be used during concomitant use with Osteomed.


The bioavailability of alendronate was slightly decreased when Osteomed and levothyroxine were co-administered to healthy subjects.

Osteomed side effects

See also:
What are the possible side effects of Osteomed?

Applies to alendronate: oral solution, oral tablet, oral tablet effervescent

In addition to its needed effects, some unwanted effects may be caused by alendronate (the active ingredient contained in Osteomed). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking alendronate:

More common:

  • Abdominal or stomach pain
Less common:
  • Difficulty with swallowing
  • heartburn
  • irritation or pain of the esophagus
  • muscle pain
  • Skin rash
Incidence not known:
  • Abdominal or stomach cramps
  • blistering, peeling, or loosening of the skin
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bone, joint, or muscle pain, severe and occasionally incapacitating
  • chest pain
  • chills
  • confusion
  • convulsions
  • cough
  • diarrhea
  • difficulty with breathing
  • difficulty with moving
  • heartburn
  • heavy jaw feeling
  • hives or welts
  • irregular heartbeats
  • itching
  • joint pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loosening of a tooth
  • muscle aching or cramping
  • muscle cramps in the hands, arms, feet, legs, or face
  • numbness and tingling around the mouth, fingertips, or feet
  • pain or burning in the throat
  • pain, swelling, or numbness in the mouth or jaw
  • rapid weight gain
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness of the skin
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots on the lips or tongue or inside the mouth
  • swollen joints
  • tingling of the hands or feet
  • tremor
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting

Minor Side Effects

Some of the side effects that can occur with alendronate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

  • Constipation
  • diarrhea
  • full or bloated feeling
  • gas
  • headache
  • nausea
Incidence not known:
  • Blurred vision or other change in vision
  • dizziness or lightheadedness
  • eye pain
  • feeling of constant movement of self or surroundings
  • general feeling of discomfort or illness
  • hair loss or thinning of the hair
  • sensation of spinning
  • sensitivity of the eye to light
  • tearing

Osteomed contraindications

See also:
What is the most important information I should know about Osteomed?

Osteomed is contraindicated in patients with the following conditions:

  • Abnormalities of the esophagus which delay esophageal emptying such as stricture or achalasia
  • Inability to stand or sit upright for at least 30 minutes

Do not administer Osteomed to patients at increased risk of aspiration

  • Hypocalcemia
  • Hypersensitivity to any component of this product. Hypersensitivity reactions including urticaria and angioedema have been reported.

Active ingredient matches for Osteomed:

Alendronic Acid in Lebanon.

Colecalciferol in Singapore.

Unit description / dosage (Manufacturer)Price, USD
Osteomed tab 20 mcg 30's (Wallace Pharm)

List of Osteomed substitutes (brand and generic names):

Osteomax tab 70 mg 8's (Solvang)
Tablet, Film-Coated; Oral; Alendronic Acid / Alendronate Sodium 70 mg (Silesia)
Ostex inj 3 mg/3 mL 1's (Nang Kuang Pharma)
Ostogee 70 mg Tablet (Swiss Pharma Pvt. Ltd.)$ 0.30
Ostomir 70 mg x 1 Blister x 4 Tablet
Tablet; Oral; Alendronic Acid / Alendronate Sodium Trihydrate 70 mg (Rider)
Liquid; Oral; Vitamin D3 / Cholecalciferol 400 units / ml
Pharmadronate 1 Blister x 4 Tablet
Pharmadronate 70 mg x 1 Blister x 4 Tablet
Tablet; Oral; Alendronic Acid / Alendronate Sodium 70 mg
PHL-alendronate tablet 70 mg (Pharmel Inc (Canada))
Tablet; Oral; Alendronic Acid / Alendronate Sodium 70 mg
Tablet; Oral; Alendronic Acid / Alendronate Sodium 70 mg
PMS-alendronate tablet 70 mg (Pharmascience Inc (Canada))
Tablet; Oral; Alendronic Acid / Alendronate Sodium 70 mg
PMS-alendronate-FC tablet 70 mg (Pharmascience Inc (Canada))
Poronil 10mg TAB / 10
10 mg x 10's


  1. DailyMed. "ALENDRONATE SODIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "ALENDRONIC ACID". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "ALENDRONIC ACID". http://www.drugbank.ca/drugs/DB00630 (accessed September 17, 2018).


The results of a survey conducted on ndrugs.com for Osteomed are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Osteomed. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet

1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Osteomed drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.

1 consumer reported time for results

To what extent do I have to use Osteomed before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Osteomed. To get the time effectiveness of using Osteomed drug by other patients, please click here.
1 day1

1 consumer reported age


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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