Panatel-125 belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
Panatel-125 is used to treat pinworms (enterobiasis; oxyuriasis).
Panatel-125 may also be used for other worm infections as determined by your doctor.
Panatel-125 works by paralyzing the worms. They are then passed in the stool.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Panatel-125 is used in certain patients with the following medical condition:
Common roundworm infection
Hookworm infection
More than one worm infection at a time
For patients taking Panatel-125 for hookworm infection :
Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Panatel-125. If you have any questions about this, check with your doctor.
Panatel-125 indications
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral
Single or mixed infections due to susceptible worms
Adult: 10 mg/kg as a single dose.
Child: 10 mg/kg as a single dose.
Oral
Ascariasis
Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr.
Oral
Necatoriasis
Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days.
Oral
Enterobiasis
Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose.
Oral
Trichinosis
Adult: 10 mg/kg daily for 5 days.
How should I use Panatel-125?
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
Use Panatel-125 as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Panatel-125 may be taken on an empty stomach or with food, milk, or juice.
Shake well before using a dose of Panatel-125.
Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
Wear tight underwear both day and night while taking Panatel-125.
Panatel-125 is usually prescribed as a single dose.
Only one dose of Panatel-125 is required. If you forget to take Panatel-125, take it as soon as you remember.
Ask your health care provider any questions you may have about how to use Panatel-125.
Panatel-125 description
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Panatel-125 is an antinematodal thiophene
Panatel-125 dosage
Panatel-125 Dosage
Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
Enterobiasis
Pinworm Infection (Enterobius vermicularis)
Hookworm Infection (Necator or Ancylostoma)
Ascariasis
Trichostrongylosis
Moniliformis Infection
Usual Pediatric Dose for:
Enterobiasis
Pinworm Infection (Enterobius vermicularis)
Hookworm Infection (Necator or Ancylostoma)
Ascariasis
Trichostrongylosis
Moniliformis Infection
Additional dosage information:
Renal Dose Adjustments
Liver Dose Adjustments
Dose Adjustments
Precautions
Dialysis
Other Comments
Usual Adult Dose for Enterobiasis
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)
11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.
Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)
11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Adult Dose for Ascariasis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Trichostrongylosis
11 mg/kg base (maximum 1 g) orally once.
Usual Adult Dose for Moniliformis Infection
11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Usual Pediatric Dose for Enterobiasis
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)
>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.
Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)
>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.
Usual Pediatric Dose for Ascariasis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Trichostrongylosis
>=2 years: 11 mg/kg base (maximum 1 g) orally once.
Usual Pediatric Dose for Moniliformis Infection
>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Panatel-125 is contraindicated in patients with hepatic disease.
Dose Adjustments
In the treatment of ascariasis, Panatel-125 may be used only if it has been determined that the worm load will not worsen obstruction.
Precautions
Panatel-125 is contraindicated in patients with hepatic disease.
When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.
Panatel-125 should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.
Other medications are known to antagonize the anthelmintic effect of Panatel-125. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Panatel-125.
Dialysis
Data not available
Other Comments
The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.
Panatel-125 pamoate 2.9 g is approximately equivalent to 1 g of Panatel-125 (base).
More about Panatel-125
Side Effects
During Pregnancy or Breastfeeding
Dosage Information
Drug Interactions
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Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.
• Praziquantel
• Cimetidine
Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.
• Theophylline
The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.
Applies to Panatel-125: oral suspension, oral tablet, oral tablet chewable
In addition to its needed effects, some unwanted effects may be caused by Panatel-125 (the active ingredient contained in Panatel-125). In the event that any of these side effects do occur, they may require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Panatel-125, check with your doctor or nurse as soon as possible:
Rare
Skin rash
Minor Side Effects
Some of the side effects that can occur with Panatel-125 may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Pyrantel (Austria, Finland, France, Germany, Israel, Luxembourg, New Zealand, Norway, Poland, South Africa, Sweden, Switzerland, United Kingdom, United States)
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