Coenzyme A (metabolite of Panthenol) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.
Only the D-Panthenol is the provitamin of D-Pantothenic acid (vitamin B5), not the L-Panthenol.
A cream with Panthenol regularly applied to the skin improves the moisture content of dry skin significantly.
A cream with 5% Panthenol accelerates the healing of superficial wounds by approximately 30%.
An ointment with Panthenol prevents erythema due to UV light.
Panthenol ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).
Panthenol is effective for preventing / treating nappy dermatitis in infants.
This medication is used to prevent or treat low blood Panthenol levels in people who do not get enough Panthenol from their diets. It may be used to treat conditions caused by low Panthenol levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough Panthenol (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).
Panthenol plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough Panthenol in the blood, then the body will take Panthenol from bones, thereby weakening bones. Having the right amount of Panthenol is important for building and keeping strong bones.
Take this medication by mouth with food. If your product contains Panthenol citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.
If you are using the chewable product, chew it well before swallowing.
If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.
If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.
If you think you may have a serious medical problem, seek immediate medical attention.
Panthenol chloride is an ionic compound of Panthenol and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.
1 or 2 tabs daily.
Dextropanthenyl alcohol in combination with hydrocortisone may be more effective than topical hydrocortisone alone in some dermatoses.
What are the possible side effects of Panthenol?
Angina pectoris, hypertension (1% to 3%).
Nasal spray: Fatigue, depression, dizziness, paresthesia (1% to 3%). Injectable: Poor appetite; abdominal pain.
Erythematous rash (1% to 3%).
Pruritus of ear lobes; skin rash.
Rhinitis (12%); abnormal lacrimation, conjunctivitis (1% to 3%).
Abdominal pain, constipation, diarrhea, dyspepsia, nausea (1% to 3%).
Nausea with or without vomiting (10%); salty taste.
Cystitis (1% to 3%).
Infection, lymphadenopathy (1% to 3%).
Inflammation at subcutaneous or IM site (10%).
Back pain (5%); arthralgia (4%); arthrosis, myalgia (1% to 3%).
Epistaxis (4%); bronchospasm, sinusitis, upper respiratory tract infection (1% to 3%).
Influenza-like symptoms (1% to 3%).
Death caused by anaphylaxis (1 case), feet edema, feverish sensation.
Haemophiliacs, patients with ileus (due to mechanical obstruction).
Calcium Pantothenate in Serbia.
Dexpanthenol in Hungary, Russia.
|Unit description / dosage (Manufacturer)||Price, USD|
|Aerosol; Topical; Vitamin B5 / Dexpanthenol 5%|
|Cream; Topical; Vitamin B5 / Dexpanthenol 5%|
|Ointment; Ophthalmic; Vitamin B5 / Dexpanthenol|
|Tablet; Oral; Vitamin B5 / Dexpanthenol 100 mg|
|Panthenol 4.63 g/100 g x 130 g x 1 Bottle|
List of Panthenol substitutes (brand and generic names):
|Panthenol Domina 5%|
|Panthenol 100mg JENAPHARM (Germany)|
|panthenol 2% (Egypt)|
|Panthenol 5% (Egypt)|
|Panthenol Chauvin (Latvia, Lithuania)|
|Panthenol Cifsa (Ecuador)|
|Panthenol Forte (Latvia)|
|Panthenol Heumann (Germany)|
|Panthenol Jenapharm (Czech Republic, Germany)|
|Panthenol Lichtenstein 5% (Germany)|
|Panthenol Muller (Latvia)|
|Panthenol Pamex (Latvia)|
|Panthenol Panax (Egypt)|
|Panthenol PharmaSwiss (Lithuania)|
|Panthenol Rth (Latvia)|
|Panthenol Spray (Georgia, Germany, Lithuania)|
|Panthenol Spray Chauvin ankerpharm (Germany)|
|Panthenol-Augensalbe Jenapharm (Germany)|
|Panthenol-Creme LAW (Germany)|
|Panthenol-Lösung Lichtenstein (Germany)|
|Panthenol-ratiopharm (Estonia, Germany, Latvia, Lithuania, Russian Federation)|
|Panthenol-Salbe Lichtenstein (Germany)|
|Panthenolspray (Russian Federation)|
|Aerosol; Topical; Vitamin B5 / Dexpanthenol 4.63%|
|Pantho 5% (Egypt)|
|Pantho 7.5% (Egypt)|
|Ointment; Topical; Vitamin B5 / Dexpanthenol 5% (Akrikhin)|
|Panthol (Slovenia, Taiwan)|
|Panthol 100 mg/1 mL x 1 mL|
|Panthol 100 mg/1 mL x 2 mL|
|Panto Liquid (Austria)|
|Pantol (Japan, Oman)|
|40 mg x 10's (Siomond)||$ 0.70|
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Information checked by Dr. Sachin Kumar, MD Pharmacology