Perebron Uses

Rating: 5 - 2 review(s)
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Perebron indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Perebron is a cough suppressant with a predominantly peripheral action that has been used for non-productive cough

Perebron dosage

Dosing regimen of Oxo is individual. Daily dose of 200-800 mg, the multiplicity of application 2 times / day. For patients with impaired renal function (creatinine clearance 20-50 ml / min), the first dose is 200 mg, then 100 mg every 24 hours. When CC is less than 20 ml / min, the first dose is 200 mg, then 100 mg every 48 hours.

Perebron interactions

Simultaneous administration of Oxo with:

  • antacids containing calcium, magnesium or aluminum, with sucralfate, with preparations containing two-and trivalent cations, such as iron, or multivitamins containing zinc it may be in breach absorption of quinolones, resulting in a decrease in their concentration in the body. These medications should not be used for 2 hours before or within 2 hours after taking ofloxacin.
  • NSAIDs increases the risk of stimulating effect on the central nervous system and seizures.
  • theophylline may increase its concentration in blood plasma (including the equilibrium state), increasing half-life. This increases the risk of adverse reactions associated with the action of theophylline.
  • beta-lactam antibiotics, aminoglycosides and metronidazole there were observed additive interaction.

    Perebron side effects

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    Digestive system: nausea, vomiting, diarrhea, abdominal pain and cramps, appetite loss, dry mouth, flatulence, gastrointestinal dysfunction, constipation; rarely - liver damage, liver necrosis, jaundice, hepatitis, intestinal perforation, pseudomembranous colitis, bleeding from the gastrointestinal tract, disorders of the oral mucosa, heartburn, elevated liver enzymes, including GGT and LDH, increased serum bilirubin.

    CNS and peripheral nervous system: insomnia, dizziness, fatigue, drowsiness, nervousness; rarely - convulsions, anxiety, cognitive changes, depression, abnormal dreams, euphoria, hallucinations, paresthesia, syncope, tremor, confusion, nystagmus, suicidal thoughts or attempts, disorientation, psychotic reactions, paranoia, phobia, agitation, aggressiveness, emotional instability, peripheral neuropathy, ataxia, incoordination, exacerbation of extrapyramidal disorders, speech disorder.

    Allergic reactions: skin rash, itching, rarely - angioedema, urticaria, vasculitis, allergic pneumonitis, anaphylactic shock, erythema multiforme, Stevens-Johnson syndrome, erythema nodosum, exfoliative dermatitis, toxic epidermal necrolysis, conjunctivitis.

    Sexual system: an itch on the external genitalia in women, vaginitis, vaginal discharge; rare - burning, irritation, pain and rash in the genital area of women, dysmenorrhea, menorrhagia, metrorrhagia, vaginal candidiasis.

    Cardiovascular system: rarely - heart failure, edema, hypertension, hypotension, palpitation, vasodilatation, cerebral thrombosis, pulmonary edema, and tachycardia.

    Urinary system: rarely - dysuria, urinary frequency, urinary retention, anuria, polyuria formation of kidney stones, kidney failure, nephritis, hematuria, albuminuria, candiduria.

    Musculoskeletal system: rarely - arthralgia, myalgia, tendonitis, muscle weakness, exacerbation of myasthenia gravis.

    Metabolism: rarely - thirst, weight loss, hyper- or hypoglycemia (especially in patients with diabetes mellitus receiving insulin or oral hypoglycemic agents), acidosis, increase in serum triglycerides, cholesterol, potassium.

    Respiratory system: rarely - cough, runny nose, respiratory failure, dyspnea, bronchospasm, stridor.

    Sensory organs: rarely - hearing loss, tinnit, diplopia, nystagmus, impaired clarity of vision, disturbances of taste, smell, photophobia.

    Dermatological reactions: rarely - photosensitivity, hyperpigmentation, vesicle-bullous eruption.

    Hematopoietic system: rarely - anemia, hemorrhage, pancytopenia, agranulocytosis, leukopenia, reversible suppression of bone marrow hematopoiesis, thrombocytopenia, thrombocytopenic purpura, petechiae, ecchymosis, increased prothrombin time.

    Other: chest pain, sore throat, fever, body aches, rarely - fatigue, chills, malaise, epistaxis, increased sweating.

    Perebron contraindications

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    * you are allergic to any ingredient in Dextromethorphan/Guaifenesin

    * you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

    * you are taking a selective serotonin reuptake inhibitor (SSRI) (eg, fluoxetine)

    Active ingredient matches for Perebron:

    Oxolamine in Chile, Greece, Turkey, Venezuela.

    Oxolamine citrate or oxolamine phosphate in Venezuela.

    Oxolamine phosphate in Turkey.


    Unit description / dosage (Manufacturer)Price, USD
    Syrup; Oral; Oxolamine Citrate 28 mg / 5 ml
    Syrup; Oral; Oxolamine Phosphate 50 mg / 5 ml

    List of Perebron substitutes (brand and generic names):

    Syrup; Oral; Oxolamine Citrate 28 mg / 5 ml (Andromaco)
    Syrup; Oral; Oxolamine Phosphate 50 mg / 5 ml (Andromaco)
    Syrup; Oral; Oxolamine Citrate 1% (Teva)
    Syrup; Oral; Oxolamine Citrate 1%
    Syrup; Oral; Oxolamine Citrate 1%
    Syrup; Oral; Oxolamine 28 mg / 5 ml (Konsuma)
    Syrup; Oral; Oxolamine 50 mg / 5 ml (Konsuma)
    Zeco 100 mg

    Reviews

    The results of a survey conducted on ndrugs.com for Perebron are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Perebron. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

    User reports

    Consumer reported useful

    No survey data has been collected yet


    1 consumer reported price estimates

    Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
    The below mentioned numbers have been reported by ndrugs.com website users about whether the Perebron drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
    Users%
    Expensive1
    100.0%


    1 consumer reported time for results

    To what extent do I have to use Perebron before I begin to see changes in my health conditions?
    As part of the reports released by ndrugs.com website users, it takes 1 week and a few days before you notice an improvement in your health conditions.
    Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Perebron. To get the time effectiveness of using Perebron drug by other patients, please click here.
    Users%
    1 week1
    100.0%


    26 consumers reported age

    Users%
    30-458
    30.8%
    1-57
    26.9%
    16-296
    23.1%
    6-153
    11.5%
    > 601
    3.8%
    46-601
    3.8%


    Consumer reviews

    Ahamd Bilal Bakhtyari 23 Dec 2021 08:44
    For adult age of between 25 to 40, 5mg 3 times in a day. Will be effective


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    Information checked by Dr. Sachin Kumar, MD Pharmacology

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