Phenylephrine Tannate Uses

sponsored
How do you administer this medicine?

What is Phenylephrine Tannate?

Relieving congestion due to colds, flu, hay fever, and other allergies. It may also be used for other conditions as determined by your doctor.

Phenylephrine Tannate suspension is a decongestant. It works by shrinking swollen and congested nasal tissues by constricting blood vessels. This results in relief of congestion (stuffy feeling) and improved breathing through the nose.

Phenylephrine Tannate indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
sponsored

Phenylephrine Tannate is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs. (Hemorrhoids; Hypotension; Nasal congestion; Paroxysmal supraventricular tachycardia; vascular failure;)

How should I use Phenylephrine Tannate?

Use Phenylephrine Tannate suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Phenylephrine Tannate suspension may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Shake well before using.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of Phenylephrine Tannate suspension and are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Phenylephrine Tannate suspension.

Uses of Phenylephrine Tannate in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
sponsored

Use: Labeled Indications

Hypotension/shock: Treatment of hypotension, vascular failure in shock. Note: Not recommended for routine use in the treatment of septic shock; use should be limited until more evidence demonstrating positive clinical outcomes becomes available (Rhodes 2017).

Guideline recommendations:

Cardiogenic shock: The 2017 American Heart Association (AHA) scientific statement for the Contemporary Management of Cardiogenic Shock recommends Phenylephrine Tannate, if needed, be considered for initial vasoactive management of cardiogenic shock due to aortic stenosis, mitral stenosis, or dynamic left ventricular outflow tract (LVOT) obstruction (AHA [van Diepen 2017]).

Hypotension during anesthesia: As a vasoconstrictor in regional analgesia

Nasal congestion: As a decongestant [OTC]

Off Label Uses

Hypotension in patients with obstructive hypertrophic cardiomyopathy

Phenylephrine Tannate is a pure alpha1 agonist that will increase systemic vascular resistance without increasing heart rate or contractility. This is advantageous in patients with obstructive hypertrophic cardiomyopathy and hypotension since increases in both heart rate and contractility may cause the obstruction to worsen, leading to a decrease in cardiac output. Other vasopressors like dopamine, epinephrine, and norepinephrine may increase contractility and/or heart rate. Additional trials may be necessary to further define the role of Phenylephrine Tannate in this condition.

Based on the American Urological Association guidelines for the management of priapism, due to the low risk of cardiovascular side effects intracavernous injection of Phenylephrine Tannate is recommended for ischemic priapism that persists following aspiration/irrigation.

Phenylephrine Tannate description

sponsored

Phenylephrine Tannate is a sympathomimetic amine that acts predominantly on α-adrenergic receptors. It is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs.

Phenylephrine Tannate dosage

Usual Adult Dose for Hypotension:

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.

Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Shock:

IM or subcutaneous: 2 to 5 mg every 1 to 2 hours as needed.

IV bolus: 0.2 mg/dose (range: 0.1 to 0.5 mg/dose) every 10 to 15 minutes as needed (initial dose should not exceed 0.5 mg)

IV infusion: 100 to 180 mcg/min initially. The usual maintenance dose is 40 to 60 mcg/min.

Alternatively, 0.5 mcg/kg/minute; titrate to desired response. Dosing ranges between 0.4 to 9.1 mcg/kg/minute have been reported.

Usual Adult Dose for Supraventricular Tachycardia:

0.25 to 0.5 mg IV over 30 seconds.

Usual Adult Dose for Nasal Congestion:

Tablets or oral liquid: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine Tannate 7.5 mg/5 mL oral liquid:

15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine Tannate 10 mg oral tablet:

10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine Tannate 10 mg oral disintegrating strip:

10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine Tannate 10 mg/5 mL oral suspension, extended release:

10 to 20 mg orally every 12 hours.

Phenylephrine Tannate 10 mg oral tablet, chewable, extended release:

10 to 20 mg orally every 12 hours.

Phenylephrine Tannate 7.5 mg/5 mL oral suspension, extended release

7.5 to 15 mg orally every 12 hours.

Usual Pediatric Dose for Hypotension:

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.

IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.

IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Shock:

IM or subcutaneous: 0.1 mg/kg every 1 to 2 hours as needed. Maximum dose: 5 mg.

IV bolus: 5 to 20 mcg/kg/dose every 10 to 15 minutes as needed.

IV: 0.1 to 0.5 mcg/kg/min titrated to effect.

Usual Pediatric Dose for Supraventricular Tachycardia:

5 to 10 mcg/kg IV over 30 seconds.

Usual Pediatric Dose for Nasal Congestion:

Phenylephrine Tannate 1.25 mg/0.8 mL oral liquid:

2 years to 5 years: 1.6 mL orally every 4 hours not to exceed 6 doses daily.

Chewable tablets or oral liquid:

6 years to 11 years: 10 mg orally every 4 hours as needed.

12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine Tannate 7.5 mg/5 mL oral liquid:

2 years to 5 years: 3.75 mg orally every 6 hours not to exceed 15 mg daily.

6 years to 11 years: 7.5 mg orally every 6 hours not to exceed 30 mg daily.

12 years or older: 15 mg orally every 6 hours not to exceed 60 mg daily.

Phenylephrine Tannate 10 mg oral tablet:

12 years or older: 10 mg orally every 4 to 6 hours not to exceed 4 doses daily.

Phenylephrine Tannate 10 mg oral tablet, disintegrating:

2 years to 5 years: 5 mg orally every 4 hours as needed.

6 years to 11 years: 10 mg orally every 4 hours as needed.

12 years or older: 10 to 20 mg orally every 4 hours as needed.

Phenylephrine Tannate 10 mg/5 mL oral suspension, extended release:

12 years or older: 10 to 20 mg orally every 12 hours.

6 years to 11 years: 5 to 10 mg orally every 12 hours.

Phenylephrine Tannate 10 mg oral disintegrating strip:

12 years or older: 10 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine Tannate 10 mg oral tablet, chewable, extended release:

6 years to 11 years: 5 to 10 mg orally every 12 hours.

12 years or older: 10 to 20 mg orally every 12 hours.

Phenylephrine Tannate 7.5 mg/5 mL oral suspension, extended release

2 years to 5 years: 1.25 to 2.5 mL orally every 12 hours.

6 years to 11 years: 2.5 to 5 mL orally every 12 hours.

12 years or older: 5 to 10 mL orally every 12 hours.

Phenylephrine Tannate 1.25 mg oral disintegrating strip:

2 years to 3 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.

Phenylephrine Tannate 2.5 mg oral disintegrating strip:

2 years to 5 years: 2.5 mg orally every 4 hours, not to exceed 15 mg in 24 hours.

6 years to 11 years: 5 mg orally every 4 hours, not to exceed 30 mg in 24 hours.

Phenylephrine Tannate 1.25 mg oral tablet, chewable:

12 years or older: 5 mg orally every 4 hours not to exceed 6 doses daily.

Phenylephrine Tannate 2.5 mg/5 mL oral liquid:

4 years to 5 years: 5 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

6 years to 11 years: 10 mL orally every 4 hours, not to exceed 6 doses in 24 hours.

Phenylephrine Tannate interactions

See also:
What other drugs will affect Phenylephrine Tannate?

sponsored

Acetaminophen: May increase the serum concentration of Phenylephrine Tannate (Systemic). Monitor therapy

Alpha1-Blockers: May diminish the vasoconstricting effect of Alpha1-Agonists. Similarly, Alpha1-Agonists may antagonize Alpha1-Blocker vasodilation. Monitor therapy

AtoMOXetine: May enhance the hypertensive effect of Sympathomimetics. AtoMOXetine may enhance the tachycardic effect of Sympathomimetics. Monitor therapy

Benzylpenicilloyl Polylysine: Alpha1-Agonists may diminish the diagnostic effect of Benzylpenicilloyl Polylysine. Management: Consider use of a histamine skin test as a positive control to assess a patient's ability to mount a wheal and flare response. Consider therapy modification

Cannabinoid-Containing Products: May enhance the tachycardic effect of Sympathomimetics. Exceptions: Cannabidiol. Monitor therapy

Chloroprocaine: May enhance the hypertensive effect of Phenylephrine Tannate (Systemic). Monitor therapy

CloZAPine: May diminish the therapeutic effect of Phenylephrine Tannate (Systemic). Monitor therapy

Cocaine (Topical): May enhance the hypertensive effect of Sympathomimetics. Management: Consider alternatives to use of this combination when possible. Monitor closely for substantially increased blood pressure or heart rate and for any evidence of myocardial ischemia with concurrent use. Consider therapy modification

Doxofylline: Sympathomimetics may enhance the adverse/toxic effect of Doxofylline. Monitor therapy

Ergot Derivatives: May enhance the hypertensive effect of Alpha1-Agonists. Ergot Derivatives may enhance the vasoconstricting effect of Alpha1-Agonists. Exceptions: Ergoloid Mesylates; Nicergoline. Avoid combination

FentaNYL: Alpha1-Agonists may decrease the serum concentration of FentaNYL. Specifically, fentanyl nasal spray serum concentrations may decrease and onset of effect may be delayed. Monitor therapy

Guanethidine: May enhance the arrhythmogenic effect of Sympathomimetics. Guanethidine may enhance the hypertensive effect of Sympathomimetics. Monitor therapy

Hyaluronidase: May enhance the vasoconstricting effect of Phenylephrine Tannate (Systemic). Management: Avoid the use of hyaluronidase to enhance dispersion or absorption of Phenylephrine Tannate. Use of hyaluronidase for other purposes in patients receiving Phenylephrine Tannate may be considered as clinically indicated. Avoid combination

Iobenguane Radiopharmaceutical Products: Alpha1-Agonists may diminish the therapeutic effect of Iobenguane Radiopharmaceutical Products. Management: Discontinue all drugs that may inhibit or interfere with catecholamine transport or uptake for at least 5 biological half-lives before iobenguane administration. Do not administer these drugs until at least 7 days after each iobenguane dose. Avoid combination

Ioflupane I 123: Phenylephrine Tannate (Systemic) may diminish the diagnostic effect of Ioflupane I 123. Monitor therapy

Linezolid: May enhance the hypertensive effect of Sympathomimetics. Management: Reduce initial doses of sympathomimetic agents, and closely monitor for enhanced pressor response, in patients receiving linezolid. Specific dose adjustment recommendations are not presently available. Consider therapy modification

Monoamine Oxidase Inhibitors: May enhance the hypertensive effect of Alpha1-Agonists. While linezolid is expected to interact via this mechanism, management recommendations differ from other monoamine oxidase inhibitors. Refer to linezolid specific monographs for details. Exceptions: Linezolid. Avoid combination

Ozanimod: May enhance the hypertensive effect of Sympathomimetics. Management: Concomitant use of ozanimod with sympathomimetic agents is not recommended. If combined, monitor patients closely for the development of hypertension, including hypertensive crises. Consider therapy modification

Propacetamol: May increase the serum concentration of Phenylephrine Tannate (Systemic). Management: Monitor patients closely for increased side effects of Phenylephrine Tannate if propacetamol is used concomitantly. Patients with underlying blood pressure issues or arrhythmias may need closer monitoring and may warrant consideration of alternative therapies. Monitor therapy

Solriamfetol: Sympathomimetics may enhance the hypertensive effect of Solriamfetol. Sympathomimetics may enhance the tachycardic effect of Solriamfetol. Monitor therapy

Sympathomimetics: May enhance the adverse/toxic effect of other Sympathomimetics. Monitor therapy

Tedizolid: May enhance the hypertensive effect of Sympathomimetics. Tedizolid may enhance the tachycardic effect of Sympathomimetics. Monitor therapy

Tricyclic Antidepressants: May enhance the therapeutic effect of Alpha1-Agonists. Tricyclic Antidepressants may diminish the therapeutic effect of Alpha1-Agonists. Monitor therapy

Phenylephrine Tannate side effects

See also:
What are the possible side effects of Phenylephrine Tannate?

Applies to Phenylephrine Tannate: intravenous solution

As well as its needed effects, Phenylephrine Tannate may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking Phenylephrine Tannate, check with your doctor or nurse immediately:

Incidence not known:

  • Blurred vision
  • chest pain or discomfort
  • difficult or labored breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • nausea or vomiting
  • nervousness
  • pain in the shoulders, arms, jaw, or neck
  • pounding in the ears
  • sweating
  • tightness in the chest
  • unusual tiredness

If any of the following symptoms of overdose occur while taking Phenylephrine Tannate, get emergency help immediately:

Symptoms of overdose:

  • Feeling of fullness in the head
  • pounding or rapid pulse
  • tingling in the arms or legs
  • vomiting

Minor Side Effects

Some Phenylephrine Tannate side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:

  • Heartburn
  • itching skin
  • nausea
  • pain in the neck
  • pain or discomfort in chest, upper stomach, or throat

Phenylephrine Tannate contraindications

See also:
What is the most important information I should know about Phenylephrine Tannate?

Ophthalmic solutions of Phenylephrine Tannate (Phenylephrine Tannate hydrochloride ophthalmic solution) hydrochloride are contraindicated in persons with narrow angle glaucoma (and in those individuals who are hypersensitive to Phenylephrine Tannate (Phenylephrine Tannate hydrochloride ophthalmic solution) ). Phenylephrine Tannate (Phenylephrine Tannate hydrochloride ophthalmic solution) hydrochloride 10 percent ophthalmic solutions are contraindicated in infants and in patients with aneurysms.

Active ingredient matches for Phenylephrine Tannate:

Phenylephrine Tannate


List of Phenylephrine Tannate substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD

References

  1. PubChem. "phenylephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "phenylephrine". http://www.drugbank.ca/drugs/DB00388 (accessed September 17, 2018).
  3. MeSH. "Cardiotonic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Phenylephrine Tannate are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Phenylephrine Tannate. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


Consumer reported time for results

No survey data has been collected yet


Consumer reported age

No survey data has been collected yet


Consumer reviews


There are no reviews yet. Be the first to write one!


Your name: 
Email: 
Spam protection:  < Type 21 here

Information checked by Dr. Sachin Kumar, MD Pharmacology

| Privacy Policy
This site does not supply any medicines. It contains prices for information purposes only.
© 2003 - 2021 ndrugs.com All Rights Reserved