What are the possible side effects of Phenylephrine?
Get emergency medical help if you have any of these signs of an allergic reaction to Phenylephrine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Phenylephrine and call your doctor at once if you have:
fast, pounding, or uneven heartbeat;
severe dizziness or anxiety;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
dangerously high blood pressure (severe headache, blurred vision, ringing in your ears, anxiety, confusion, chest pain, trouble breathing, uneven heart rate, seizure).
Common Phenylephrine side effects may include:
loss of appetite;
warmth, tingling, or redness under your skin;
feeling restless or excited (especially in children);
sleep problems (insomnia); or
skin rash or itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Phenylephrine in details
Applies to Phenylephrine: intravenous solution
In addition to its needed effects, some unwanted effects may be caused by Phenylephrine (the active ingredient contained in Phenylephrine). In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking Phenylephrine, check with your doctor or nurse immediately:
Incidence not known:
- Blurred vision
- chest pain or discomfort
- difficult or labored breathing
- fast, slow, or irregular heartbeat
- nausea or vomiting
- pain in the shoulders, arms, jaw, or neck
- pounding in the ears
- tightness in the chest
- unusual tiredness
If any of the following symptoms of overdose occur while taking Phenylephrine, get emergency help immediately:
Symptoms of overdose:
- Feeling of fullness in the head
- pounding or rapid pulse
- tingling in the arms or legs
Minor Side Effects
Some of the side effects that can occur with Phenylephrine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Incidence not known:
- itching skin
- pain in the neck
- pain or discomfort in chest, upper stomach, or throat
What is the most important information I should know about Phenylephrine?
- Phenylephrine orally disintegrating strips may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Phenylephrine orally disintegrating strips with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- If your symptoms do not get better within 7 days, if they get worse, or if they occur with a fever, check with your doctor.
- Phenylephrine orally disintegrating strips has Phenylephrine in it. Before you start any new medicine, check the label to see if it has Phenylephrine or pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Do not take diet or appetite control medicines while you are taking Phenylephrine orally disintegrating strips.
- If you have trouble sleeping, ask your pharmacist or doctor about the best time to take Phenylephrine orally disintegrating strips.
- Tell your doctor or dentist that you take Phenylephrine orally disintegrating strips before you receive any medical or dental care, emergency care, or surgery.
- Diabetes patients - Phenylephrine orally disintegrating strips may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Use Phenylephrine orally disintegrating strips with caution in the ELDERLY; they may be more sensitive to its effects.
- Caution is advised when using Phenylephrine orally disintegrating strips in CHILDREN; they may be more sensitive to its effects.
- Different brands of Phenylephrine orally disintegrating strips may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
- Phenylephrine orally disintegrating strips should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Phenylephrine orally disintegrating strips while you are pregnant. Phenylephrine orally disintegrating strips is found in breast milk. Do not breast-feed while taking Phenylephrine orally disintegrating strips.
Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.
If you wear contact lenses, remove them before applying Phenylephrine ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Phenylephrine ophthalmic may contains preservative (benzalkonium chloride), which may cause discoloration of contact lenses.
Do not use Phenylephrine ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.
Use caution when driving, operating machinery, or performing other hazardous activities. Phenylephrine ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.
- European Chemicals Agency - ECHA. "Phenylephrine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
- HSDB. "PHENYLEPHRINE". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
- NCIt. "Phenylephrine: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
ReviewsThe results of a survey conducted on ndrugs.com for Phenylephrine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Phenylephrine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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Information checked by Dr. Sachin Kumar, MD Pharmacology