Pregnancy of Phenyleprine Hydrochloride Wu Fu in details
Phenyleprine Hydrochloride Wu Fu crosses the placenta at term.
Maternal use of Phenyleprine Hydrochloride Wu Fu during the first trimester of pregnancy is not strongly associated with an increased risk of fetal malformations; maternal dose and duration of therapy were not reported in available publications. Phenyleprine Hydrochloride Wu Fu is available over-the-counter for the symptomatic relief of nasal congestion. Decongestants are not the preferred agents for the treatment of rhinitis during pregnancy.
Oral Phenyleprine Hydrochloride Wu Fu should be avoided during the first trimester of pregnancy; short-term use (<3 days) of intranasal Phenyleprine Hydrochloride Wu Fu may be beneficial to some patients although its safety during pregnancy has not been studied. Phenyleprine Hydrochloride Wu Fu injection is used at delivery for the prevention and/or treatment of maternal hypotension associated with spinal anesthesia in women undergoing cesarean section. Phenyleprine Hydrochloride Wu Fu may be associated with a more favorable fetal acid base status than ephedrine; however, overall fetal outcomes appear to be similar. Nausea or vomiting may be less with Phenyleprine Hydrochloride Wu Fu than ephedrine but is also dependent upon blood pressure control. Phenyleprine Hydrochloride Wu Fu may be preferred in the absence of maternal bradycardia.
Phenyleprine Hydrochloride Wu Fu breastfeeding
Small amounts of Phenyleprine Hydrochloride Wu Fu are secreted in breast milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
See references
References for pregnancy information
- "Product Information. Lusonal (Phenyleprine Hydrochloride Wu Fu)." Wraser Pharmaceuticals, Ridgeland, MS.
References for breastfeeding information
- "Product Information. Lusonal (Phenyleprine Hydrochloride Wu Fu)." Wraser Pharmaceuticals, Ridgeland, MS.
References
- PubMed Health. "Neo-Synephrine: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Phenylephrine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
- FDA Pharm Classes. "FDA Pharmacological Classification: FDA published a final rule that amended the requirements for the content and format of approved labeling (prescribing information) for human prescription drug and biological products in January 2006.". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
