The dose of a drug and dosage of the drug are two different terminologies. Dose is defined as the quantity or amount of medicine given by the doctor or taken by the patient at a given period. Dosage is the regimen prescribed by the doctor about how many days and how many times per day the drug is to be taken in specified dose by the patient. The dose is expressed in mg for tablets or gm, micro gm sometimes, ml for syrups or drops for kids syrups. The dose is not fixed for a drug for all conditions, and it changes according to the condition or a disease. It also changes on the age of the patient.
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Phenylpropanolamine HCl Dosage
Applies to the following strengths: 75 mg; 25 mg; 37.5 mg; 50 mg; 180 mg-75 mg
Usual Adult Dose for:
Nasal Congestion
Weight Loss
Usual Pediatric Dose for:
Nasal Congestion
Additional dosage information:
Renal Dose Adjustments
Other Comments
Usual Adult Dose for Nasal Congestion
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Usual Adult Dose for Weight Loss
25 mg orally 3 times a day, one-half hour before meals.
-or-
75 mg orally extended release once a day in the morning.
The use of Phenylpropanolamine HCl for weight loss should be limited to 12 weeks.
Usual Pediatric Dose for Nasal Congestion
2 to 6 years:
6.25 mg orally every 4 hours. Maximum daily dose is 37.5 mg.
6 to 12 years:
12.5 mg orally every 4 hours. Maximum daily dose is 75 mg.
> 12 years:
25 mg orally every 4 hours.
-or-
75 mg orally extended release every 12 hours.
Not to exceed 150 mg/day.
Renal Dose Adjustments
Because Phenylpropanolamine HCl is eliminated primarily by the kidneys, one-half of the normally recommended dosage should be given. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using Phenylpropanolamine HCl.
Other Comments
In November 2000, the Food and Drug Administration (FDA), in response to reports of increased risk of hemorrhagic stroke, requested that all drug companies discontinue marketing products containing Phenylpropanolamine HCl.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Phenylpropanolamine HCl
Phenylpropanolamine HCl Side Effects
During Pregnancy
Drug Interactions
Support Group
2 Reviews
Drug class: decongestants
Related treatment guides
Weight Loss
Cold Symptoms
Nasal Congestion
What other drugs will affect Phenylpropanolamine HCl?
Do not take Phenylpropanolamine HCl if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.
Phenylpropanolamine HCl may also interact with the following medicines:
furazolidone (Furoxone);
guanethidine (Ismelin);
indomethacin (Indocin);
methyldopa (Aldomet);
bromocriptine (Parlodel);
caffeine in cola, tea, coffee, chocolate, and other products;
tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), and nortriptyline (Pamelor);
other commonly used tricyclic antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil);
phenothiazines such as chlorpromazine (Thorazine), thioridazine (Mellaril), and prochlorperazine (Compazine); and
other commonly used phenothiazines, including fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), and trifluoperazine (Stelazine).
Drugs other than those listed here may also interact with Phenylpropanolamine HCl. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Phenylpropanolamine HCl interactions
Interactions are the effects that happen when the drug is taken along with the food or when taken with other medications. Suppose if you are taking a drug Phenylpropanolamine HCl, it may have interactions with specific foods and specific medications. It will not interact with all foods and medications. The interactions vary from drug to drug. You need to be aware of interactions of the medicine you take. Most medications may interact with alcohol, tobacco, so be cautious.
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It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you take this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
You should not take other medicines that contain paracetamol in combination with this medicine, as this can easily result in exceeding the maximum recommended daily dose of paracetamol. Many cold and flu remedies and over-the-counter painkillers contain paracetamol, so be sure to check the ingredients of any other medicines before taking them with this one. Migraleve yellow can be taken four hours after taking Migraleve pink if you still have a migraine, but make sure you do not exceed the maximum dose recommended in the information leaflet.
This medicine should be used with caution in people taking a monoamine oxidase inhibitor (MAOI), for example the antidepressants phenelzine, tranylcypromine or isocarboxacid. Ask your doctor or pharmacist for advice before taking this medicine if you have taken an MAOI in the last 14 days.
Cholestyramine reduces the absorption of paracetamol from the gut. It should not be taken within an hour of taking paracetamol or the effect of the paracetamol will be reduced.
Metoclopramide and domperidone may increase the absorption of paracetamol from the gut.
Long-term or regular use of paracetamol may increase the anti-blood-clotting effect of warfarin and other anticoagulant medicines, leading to an increased risk of bleeding. This effect does not occur with occasional painkilling doses. If you are taking an anticoagulant medicine and you are also taking co-codamol regularly, your blood clotting time (INR) should be regularly monitored.
In the unlikely event that this medicine makes you feel drowsy, this may be enhanced by other medicines that can cause drowsiness, such as the following:
The results of a survey conducted on ndrugs.com for Phenylpropanolamine HCl are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Phenylpropanolamine HCl. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
User reports
Consumer reported frequency of use
No survey data has been collected yet
4 consumers reported doses
What doses of Phenylpropanolamine HCl drug you have used? The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Phenylpropanolamine HCl drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users
%
11-50mg
2
50.0%
6-10mg
1
25.0%
201-500mg
1
25.0%
Consumer reviews
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