Prasterone Overdose

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What happens if I overdose Prasterone?

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Prasterone:

Store Prasterone at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Most herbal products are not packaged in childproof containers. Keep Prasterone out of the reach of children and away from pets.

Overdose of Prasterone in details

When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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No information provided.

What should I avoid while taking Prasterone?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Prasterone warnings

Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.

Current or Past History of Breast Cancer

Estrogen is a metabolite of Prasterone. Use of exogenous estrogen is contraindicated in women with a known or suspected history of breast cancer. Prasterone has not been studied in women with a history of breast cancer.

What should I discuss with my healthcare provider before taking Prasterone?

Some medical conditions may interact with Prasterone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

Some MEDICINES MAY INTERACT with Prasterone. Tell your health care provider if you are taking any other medicines, especially any of the following:

This may not be a complete list of all interactions that may occur. Ask your health care provider if Prasterone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Prasterone precautions

Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Current Or Past History Of Breast Cancer

Estrogen is a metabolite of Prasterone. Use of exogenous estrogen is contraindicated in women with a known or suspected history of breast cancer. Prasterone has not been studied in women with a history of breast cancer.

Patient Counseling Information

Advise the patient to read FDA-approved patient labeling (PATIENT INFORMATION and Instructions for Use).

Vaginal Discharge

Inform postmenopausal women that vaginal discharge may occur with Prasterone.

Abnormal Pap Smear Findings

Inform postmenopausal women that abnormal Pap smear findings may occur with Prasterone.

Nonclinical Toxicology

Carcinogenesis, Mutagenesis, Impairment Of Fertility

Carcinogenesis

Long-term studies in animals to evaluate carcinogenic potential have not been conducted with Prasterone. Two metabolites of Prasterone, testosterone and estradiol, are carcinogenic in animals.

Mutagenesis

Prasterone was not genotoxic in the in vitro bacterial mutagenesis assay (Ames test), the in vitro chromosomal aberrations assay with human peripheral blood lymphocytes, and in vivo in the mouse bone marrow micronucleus assay.

Fertility

Fertility studies were not conducted with Prasterone.

Use In Specific Populations

Pregnancy

Risk Summary

Prasterone is indicated only in postmenopausal women. There are no data with Prasterone use in pregnant women regarding any drug-associated risks. Animal reproduction studies have not been conducted with Prasterone.

Lactation

Risk Summary

Prasterone is indicated only in postmenopausal women. There is no information on the presence of Prasterone in human milk, the effects on the breastfed infant, or the effects on milk production.

Pediatric Use

Safety and effectiveness have not been established in pediatric patients.

Geriatric Use

Of the 1522 Prasterone-treated postmenopausal women enrolled in the four placebo-controlled 12-week and one open-label 52-week clinical trial, 19 and 11 percent, respectively, were 65 years of age or older.

Renal Impairment

The effect of renal impairment on the pharmacokinetics of Prasterone has not been studied.

Hepatic Impaitment

The effect of hepatic impairment on the pharmacokinetics of Prasterone has not been studied.

What happens if I miss a dose of Prasterone?

When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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