Pro-Dafalgan Uses

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How do you administer this medicine?

Pro-Dafalgan indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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It is given if the patient is unable to take oral or rectally delivered paracetamol and non-steroidal anti-inflammatory drugs are contraindicated. The onset of analgaesia from Pro-Dafalgan is more rapid than paracetamol given orally. 2g of Pro-Dafalgan are equivalent to 1g of paracetamol.

Pro-Dafalgan description

Pro-Dafalgan is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it more water-soluble. It is used in post-operative care and is delivered by I.V. It is given if the patient is unable to take oral or rectally delivered paracetamol and non-steroidal anti-inflammatory drugs are contraindicated. The onset of analgaesia from Pro-Dafalgan is more rapid than paracetamol given orally. 2 g of Pro-Dafalgan are equivalent to 1g of paracetamol.

Pro-Dafalgan dosage

Parenteral

Pain and fever

Adult: 1-2 g every 4 hr, up to 4 times daily. May be given via IM/IV inj. Max dose: 8 g daily.

Child: 20-30 mg/kg, given over 15 min, up to 4 times daily. Max dose: 120 mg/kg/day.

Pro-Dafalgan side effects

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Eczema contact during the preperation by the nursing staff with risk of hyper-sensitivity reactions => Gloves

- Allergy minor, thrombocytopenia, exceptional

- Malaise, pain during a rapid injection

Pro-Dafalgan contraindications

Severe hepatic impairment, glutathione synthetase deficiency

Hypersensitivity to paracetamol and Pro-Dafalgan, In particular with nursing staff in

1 st trimester

Active ingredient matches for Pro-Dafalgan:

Propacetamol in Luxembourg.

Propacetamol Hcl

Propacetamol hydrochloride in Switzerland.


Unit description / dosage (Manufacturer)Price, USD
Pro-Dafalgan 1 g x 2 caГ«p goГ m caГ» 1 tube dung mobi 5 mL
Pro-Dafalgan 1 g x 5 caГ«p goГ m caГ» 1 tube dung mobi 5 mL

List of Pro-Dafalgan substitutes (brand and generic names):

Injectable; Injection; Propacetamol Hydrochloride 1 g
Injectable; Injection; Propacetamol Hydrochloride 2 g
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Repigon 1 g x 10 Bottle boät in 10 tube dung mobi pha tieâm
Injectable; Injection; Propacetamol Hydrochloride

References

  1. PubChem. "Propacetamol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "Propacetamol". http://www.drugbank.ca/drugs/DB09288 (accessed September 17, 2018).
  3. MeSH. "Anti-Inflammatory Agents, Non-Steroidal". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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