Proloc-D indications
Symptomatic management of burning in various acid peptic disorders associated w/ nausea & vomiting; GERD, non-ulcer dyspepsia, gastroparesis & idiopathic hiccup or any other peptic disease accompanied by nausea &/or vomiting.
Proloc-D description
Each capsule contains Pantoprazole (Proloc-D) sodium sesquihydrate equivalent to Pantoprazole (Proloc-D) 40 mg as enteric-coated pellets and Domperidone (Proloc-D) 30 mg as sustained-release (SR) pellets.
It also contains the following excipients: Colors: Lake of indigo carmine, red ferric oxide, yellow ferric oxide and titanium dioxide (approved colors used in capsule shell).
Proloc-D is a fixed-dose combination of Pantoprazole (Proloc-D) and Domperidone (Proloc-D).
Proloc-D dosage
Usual Recommended Dose: 1 capsule daily before breakfast.
Administration: Swallow capsule whole, do not chew the capsule. The content of the vial needs to be reconstituted with 0.9% sodium chloride injection w/v 10 mL before injection. This freshly prepared solution should be administered IV over 2-15 min, either as a slow injection or it may be further diluted with 0.9% sodium chloride injection w/v 100 mL or 5% glucose injection and administered as a short-term infusion. The duration of administration should be 2-15 min. The reconstituted solution must be used within 12 hrs of preparation.
Proloc-D interactions
Pantoprazole (Proloc-D): Based on studies evaluating possible interactions of Pantoprazole (Proloc-D) with other drugs metabolized by the cytochrome P-450 system, no dosage adjustment is needed with concomitant use of the following drugs: Theophylline, cisapride, antipyrine, caffeine, carbamezapine, diazepam, diclofenac, digoxin, ethanol, glyburide, oral contraceptives (levonorgestrel/ethinyl estradiol), metoprolol, nifedipine, phenytoin or warfarin. Domperidone (Proloc-D):
Antacids and anti-secretory agents lower the oral bioavailability of Domperidone (Proloc-D). They should be taken after meals and not before meals ie, they should not be taken simultaneously with Domperidone (Proloc-D). Reduced gastric acidity impairs the absorption of Domperidone (Proloc-D).
Oral bioavailability is decreased by prior administration of cimetidine or sodium carbonate.
Proloc-D side effects
Rash, pruritus. Pantoprazole (Proloc-D): Headache, diarrhea, dizziness, GIT infections, anaphylaxis, angioedema, chest pain, dyspnea, erythema multiforme, gastroenteritis, hyperglycemia, infection, inj site reaction, jaundice, optic neuropathy, anterior ischemia, pancreatitis, speech disorder. Domperidone (Proloc-D): Dry mouth, thirst, headache, nervousness, insomnia, lethargy, irritability, GI disturbances, hot flushes, mastalgia, menstrual irregularities, urticaria, stomatitis, conjunctivitis, urinary frequency, dysuria, edema, palpitations, leg cramps, asthenia, drug intolerance, nervousness.
Proloc-D contraindications
Known hypersensitivity to Pantoprazole (Proloc-D), Domperidone (Proloc-D) or any of the excipients of Proloc-D.
Due to lack of controlled studies in pregnant and lactating women, use of Proloc-D is contraindicated in pregnancy and lactation.
Active ingredient matches for Proloc-D:
Domperidone/pantoprazole in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| 60's | $ 3.48 |
| Proloc-D Pantoprazole 20mg, Domperidone10mg CAP / 60 | $ 3.48 |
| PROLOC-D cap 10's (Comed) | $ 0.58 |
| Proloc-D Pantoprazole 20mg, Domperidone10mg CAP / 60 | $ 3.48 |
List of Proloc-D substitutes (brand and generic names): | |
| PROLOC D | |
| Proloc D 30 mg/40 mg Capsule SR (Comed Chemicals Ltd) | $ 0.08 |
| Prolus -DSR | |
| Prolus -DSR Pantoprazole 40mg, Domperidone/ SR 30mg CAP / 10 | |
| PROLUS-DM (India) | |
| 100's (Lexus) | |
| Prolus-DM Pantoprazole 40 mg, domperidone 10 mg. TAB / 100 (Lexus) | |
| PROLUS-DM tab 10's (Lexus) | |
| Prolus-DM Pantoprazole 40 mg, domperidone 10 mg. TAB / 100 (Lexus) | |
| Prolus-DSR (India) | |
| 10's (Lexus) | |
| Prolus-DSR Pantoprazole 40mg, Domperidone/ SR 30mg CAP / 10 (Lexus) | |
| PROLUS-DSR cap 10's (Lexus) | |
| PROPAN D | |
| PROPAN D 10MG/40MG TABLET 1 strip / 10 tablets each (Scortis Lab Pvt Ltd) | $ 0.72 |
| Propan D 10 mg/40 mg Tablet (Scortis Lab Pvt Ltd) | $ 0.07 |
| PROPAN-D (India) | |
| PROPAN-D tab 10's (Integra (Alfa Igra)) | $ 0.72 |
| PROPANTA DSR | |
| PROPANTA DSR 40MG/30MG CAPSULE 1 strip / 10 capsules each (Parenteral Drugs India Ltd) | $ 0.84 |
| Propanta DSR 40 mg/30 mg Capsule (Parenteral Drugs India Ltd) | $ 0.08 |
| PROPANZ D | |
| PROPANZ D 30MG/40MG TABLET 1 strip / 10 tablets each (Icarus Healthcare Pvt Ltd) | $ 1.14 |
| Propanz D 30 mg/40 mg Tablet (Icarus Healthcare Pvt Ltd) | $ 0.11 |
| PROPANZ-D (India) | |
| PROPANZ-D cap 10's (ICARUS) | $ 0.96 |
| PROPENTA D | |
| PROPENTA D 10MG/40MG TABLET 1 strip / 10 tablets each (Protech Biosystems) | $ 0.77 |
| Propenta D Tablet (Protech Biosystems) | $ 0.08 |
| PROPTOR-D (India) | |
| PROPTOR-D tab 10's (Mestra) | $ 0.60 |
| PROSAC-D (India) | |
| PROSAC-D tab 10's (Sac Pharma) | $ 0.84 |
| PROSAC-DSR (India) | |
| PROSAC-DSR cap 10's (Sac Pharma) | $ 0.95 |
| PROTERA D | |
| Protera D Capsule SR (Lupin Ltd) | $ 0.11 |
| PROTERA-D (India) | |
| PROTERA-D 10 MG/40 MG CAPSULE 1 strip / 10 capsules each (Lupin) | $ 1.00 |
| PROTERA-D cap 10's (Lupin) | $ 0.92 |
| Protocent-DSR (India) | |
| PROTOCENT-DSR cap 10's (Crescent) | $ 1.25 |
| PROTOCHEK DSR | |
| PROTOCHEK DSR 30 MG/40 MG TABLET 1 strip / 10 tablets each (Ipca Laboratories Ltd) | $ 1.02 |
| PROTOCHEK-DSR (India) | |
| PROTOCHEK-DSR cap 10's (IPCA) | $ 0.97 |
| PROTONIL D | |
| PROTONIL D 30MG/40MG TABLET 1 strip / 10 tablets each (Zeus Pharma) | $ 1.06 |
| Protonil D 30 mg/40 mg Tablet (Zeus Pharma) | $ 0.11 |
| PROTOPAN D | |
| PROTOPAN D TABLET 1 strip / 10 tablets each (East West Pharma) | $ 0.73 |
| PROTOPAN DSR | |
| PROTOPAN DSR CAPSULE 1 strip / 10 capsules each (East West Pharma) | $ 1.20 |
| Protopan-D (India) | |
| Protopan-D Pantoprazole Na 40mg, Domperidone 20mg TAB / 10 (East West) | $ 0.73 |
| 10's (East West) | $ 0.73 |
| PROTOPAN-D tab 10's (East West) | $ 0.73 |
| PROTOPAN-H (India) | |
| 10's (East West) | $ 0.37 |
| Protopan-H Pantoprazole 20mg, Domperidone10mg TAB / 10 (East West) | $ 0.37 |
| PROTOPAN-H tab 10's (East West) | $ 0.37 |
| Protopan-H Pantoprazole 20mg, Domperidone10mg TAB / 10 (East West) | $ 0.37 |
| PROVERA-D (India) | |
| 100's (Apotex) | $ 7.95 |
| Provera-D Pantoprazole 40 mg, domperidone 10 mg. TAB / 100 (Apotex) | $ 7.95 |
| PROVERA-D tab 10's (Apotex) | $ 0.80 |
See 2314 substitutes for Proloc-D | |
References
- PubChem. "pantoprazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "domperidone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "domperidone". http://www.drugbank.ca/drugs/DB01184 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Proloc-D are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Proloc-D. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Proloc-D drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
Consumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet2 consumers reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 1 | 50.0% | |
| 46-60 | 1 | 50.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
