Propranolol Side effects

• Side effects of Propranolol in details
• Propranolol contraindications
• Propranolol reviews

What are the possible side effects of Propranolol?

Get emergency medical help if you have any signs of an allergic reaction to Propranolol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• slow or uneven heartbeats;

• a light-headed feeling, like you might pass out;

• wheezing or trouble breathing;

• shortness of breath (even with mild exertion), swelling, rapid weight gain;

• sudden weakness, vision problems, or loss of coordination (especially in a child with hemangioma that affects the face or head);

• cold feeling in your hands and feet;

• depression, confusion, hallucinations;

• liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• low blood sugar - headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;

• low blood sugar in a baby - pale skin, blue or purple skin, sweating, fussiness, crying, not wanting to eat, feeling cold, drowsiness, weak or shallow breathing (breathing may stop for short periods), seizure (convulsions), or loss of consciousness; or

• severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common Propranolol side effects may include:

• nausea, vomiting, diarrhea, constipation, stomach cramps;

• decreased sex drive, impotence, or difficulty having an orgasm;

• sleep problems (insomnia); or

• tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side effects of Propranolol in details

Applies to Propranolol: oral capsule extended release, oral solution, oral tablet

Other dosage forms:

• intravenous solution

As well as its needed effects, Propranolol may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Propranolol, check with your doctor immediately:

More common: - in children

• Cough producing mucus
• difficulty with breathing
• tightness in the chest

Incidence not known:

• Abdominal or stomach pain and tenderness
• black, tarry stools
• blistering, peeling, or loosening of the skin
• blood in the urine
• bloody nose
• bloody stools
• blurred or loss of vision
• body aches or pain
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain or discomfort
• confusion about identity, place, and time
• congestion
• constipation
• cough
• cracks in the skin
• crying
• decreased awareness or responsiveness
• decreased urine output
• depersonalization
• diarrhea
• difficulty with swallowing
• dilated neck veins
• disturbed color perception
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• double vision
• dryness or soreness of the throat
• dysphoria
• euphoria
• extreme fatigue
• fast, pounding, slow, or irregular heartbeat
• fever and chills
• general feeling of discomfort, illness, or weakness
• hair loss
• halos around lights
• headaches
• heavier menstrual periods
• hoarseness
• irregular breathing
• lightheadedness, dizziness, or fainting
• loss of heat from the body
• mental depression
• mimicry of speech or movements
• muscle or joint pain
• mutism
• nausea
• negativism
• night blindness
• noisy breathing
• overbright appearance of lights
• paleness or cold feeling in the fingertips and toes
• paranoia
• peculiar postures or movements, mannerisms, or grimacing
• pinpoint red or purple spots on the skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• quick to react or overreact emotionally
• rapidly changing moods
• rectal bleeding
• red skin lesions, often with a purple center
• red, irritated eyes
• red, swollen skin
• reddening of the skin, especially around the ears
• runny nose
• scaly skin
• seeing, hearing, or feeling things that are not there
• severe sleepiness
• short-term memory loss
• shortness of breath
• skin irritation or rash, including rash that looks like psoriasis
• skin rash, hives, or itching
• sores, ulcers, or white spots in the mouth or on the lips
• sweating
• swelling of the eyes, face, fingers, feet, or lower legs
• swollen glands
• tender, swollen glands in the neck
• tightness in the chest
• tingling or pain in fingers or toes when exposed to cold
• tunnel vision
• unusual bleeding or bruising
• unusual tiredness or weakness
• voice changes
• vomiting
• weight gain

Minor Side Effects

Some Propranolol side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common: - in children

• Anxiety
• dry mouth
• hyperventilation
• irritability
• restlessness
• shaking
• sleepiness or unusual drowsiness
• trouble sleeping
• unusual dreams

Less common: - in children

• Decreased appetite

Incidence not known:

• Dry eyes
• heartburn
• loss of strength or energy
• muscle weakness
• pain or discomfort in the chest, upper stomach, or throat
• stomach cramps
• unusual drowsiness, dullness, or feeling of sluggishness
• vivid dreams

What is the most important information I should know about Propranolol?

• Propranolol may cause drowsiness, dizziness, lightheadedness, or vision changes. These effects may be worse if you use it with alcohol or certain medicines. Use Propranolol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Check with your doctor before you drink alcohol while you are using Propranolol; it may increase the risk of Propranolol's side effects.
• Do NOT use more than the recommended dose without checking with your doctor.
• Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
• Tell your doctor or dentist that you use Propranolol before you receive any medical or dental care, emergency care, or surgery.
• If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Propranolol.
• Propranolol may lower your blood sugar levels. This is most likely to happen in infants and children, or in patients who have diabetes or kidney problems. It may also occur after prolonged physical activity or during fasting. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. If this occurs, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens.
• Diabetes patients - Propranolol may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Propranolol may interfere with certain lab tests, including glaucoma screening and dobutamine stress echocardiography. Be sure your doctor and lab personnel know you are using Propranolol.
• Lab tests, including blood pressure and heart function, may be performed while you use Propranolol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Propranolol with caution in the ELDERLY; they may be more sensitive to its effects.
• Propranolol should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Propranolol while you are pregnant. Propranolol is found in breast milk. If you are or will be breast-feeding while you use Propranolol, check with your doctor. Discuss any possible risks to your baby.

If you stop taking Propranolol suddenly, you may have WITHDRAWAL symptoms. These may include worsening chest pain along with possible heart attack.

Propranolol contraindications

Hypersensitivity to Propranolol, beta-blockers, or any component of the formulation; uncompensated heart failure (unless the failure is due to tachyarrhythmias being treated with Propranolol); cardiogenic shock; severe sinus bradycardia; sick sinus syndrome; or heart block greater than first-degree (except in patients with a functioning artificial pacemaker); bronchial asthma

Hemangeol (additional contraindications): Premature infants with corrected age <5 weeks; infants weighing <2 kg; heart rate <80 bpm; blood pressure <50/30 mm Hg; pheochromocytoma; history of bronchospasm

Documentation of allergenic cross-reactivity for beta-blockers is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.

Canadian labeling: Additional contraindications (not in US labeling): Cor pulmonale; allergic rhinitis during pollen season; patients prone to hypoglycemia; hypotension (blood pressure parameters not specified in labeling); metabolic acidosis; vasospastic angina (also referred to as Prinzmetal angina or variant angina); severe peripheral arterial circulatory disturbance

Hemangiol (additional contraindications): Infants weighing <2.5 kg; breastfed infants if mother is treated with medicines contraindicated with Propranolol; heart rate <100 bpm or blood pressure <65/45 mm Hg (<3 months of age), heart rate <90 bpm or blood pressure <70/50 mm Hg (3 to <6 months of age), heart rate <80 bpm or blood pressure <80/55 mm Hg (6 to 12 months of age)

References

1. European Chemicals Agency - ECHA. "propranolol: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
2. NCIt. "Propranolol: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
3. NIST. "Propranolol". http://www.nist.gov/srd/nist1a.cfm (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Propranolol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Propranolol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reviews

There are no reviews yet. Be the first to write one!

Your name:  Email:  Spam protection:  < Type 1 here

Information checked by Dr. Sachin Kumar, MD Pharmacology