What are the possible side effects of Quinine Hydrochloride Hoei?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Quinine Hydrochloride Hoei and call your doctor at once if you have any of these serious side effects:
fever, chills, confusion, weakness, sweating;
severe vomiting, stomach pain, diarrhea;
problems with vision or hearing;
chest pain, trouble breathing, severe dizziness, fainting, fast or pounding heartbeats;
severe flushing (warmth, redness, or tingly feeling);
urinating less than usual or not at all;
weak or shallow breathing, feeling like you might pass out;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
blood in your urine or stools;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
headache, blurred vision, changes in color vision;
mild dizziness, spinning sensation, ringing in your ears;
upset stomach; or
muscle weakness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Quinine Hydrochloride Hoei in details
A side effect of any drug can be defined as the unwanted or undesired effect produced by the drug. The side effect can be major or in few medications minor that can be ignored. Side effects not only vary from drug to drug, but it also depends on the dose of the drug, the individual sensitivity of the person, brand or company which manufactures it. If side effects overweigh the actual effect of the medicine, it may be difficult to convince the patient to take the drug. Few patients get specific side effects to specific drugs; in that case, a doctor replaces the drug with another. If you feel any side effect and it troubles you, do not forget to share with your healthcare practitioner.
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Overall
Quinine Hydrochloride Hoei can adversely affect almost every body system. The most common adverse events associated with Quinine Hydrochloride Hoei use are a cluster of symptoms called “cinchonism”, which occurs to some degree in almost all patients taking Quinine Hydrochloride Hoei. Symptoms of mild cinchonism include headache, vasodilation and sweating, nausea, tinnitus, hearing impairment, vertigo or dizziness, blurred vision, and disturbance in color perception. More severe symptoms of cinchonism are vomiting, diarrhea, abdominal pain, deafness, blindness, and disturbances in cardiac rhythm or conduction. Most symptoms of cinchonism are reversible and resolve with discontinuation of Quinine Hydrochloride Hoei.
The following ADVERSE REACTIONS have been reported with Quinine Hydrochloride Hoei sulfate. Because these reactions have been reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Gastrointestinal: nausea, vomiting, diarrhea, abdominal pain, gastric irritation, and esophagitis.
Hepatobiliary: granulomatous hepatitis, hepatitis, jaundice, and abnormal liver function tests.
Metabolic: hypoglycemia and anorexia.
Musculoskeletal: myalgias and muscle weakness.
Renal: hemoglobinuria, renal failure, renal impairment, and acute interstitial nephritis.
Special Senses: visual disturbances, including blurred vision with scotomata, sudden loss of vision, photophobia, diplopia, night blindness, diminished visual fields, fixed pupillary dilatation, disturbed color vision, optic neuritis, blindness, vertigo, tinnitus, hearing impairment, and deafness.
What is the most important information I should know about Quinine Hydrochloride Hoei?
Quinine Hydrochloride Hoei may cause dizziness, light-headedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Quinine Hydrochloride Hoei with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Tell your doctor or dentist that you take Quinine Hydrochloride Hoei before you receive any medical or dental care, emergency care, or surgery.
If your symptoms do not get better within 1 to 2 days or if they get worse, or if your fever comes back after finishing treatment with Quinine Hydrochloride Hoei, check with your doctor.
Quinine Hydrochloride Hoei may cause low blood sugar. Pregnant women may be at higher risk of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens.
Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
Quinine Hydrochloride Hoei may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury.
Serious and life-threatening bleeding problems may occur with Quinine Hydrochloride Hoei. This could also lead to severe kidney problems. Tell your doctor right away if you notice symptoms of unusual bleeding or bruising (eg, bleeding gums; severe nose bleed; dark urine; black, tarry, or bloody stools; unusual purple, brown, or red spots on the skin).
Quinine Hydrochloride Hoei should NOT be used to treat or prevent nighttime leg cramps. It should also NOT be used to prevent malaria. Talk with your doctor about other ways to treat nighttime leg cramps or to prevent malaria.
Quinine Hydrochloride Hoei may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Quinine Hydrochloride Hoei.
Use Quinine Hydrochloride Hoei with caution in the ELDERLY; they may be more sensitive to its effects.
Quinine Hydrochloride Hoei should be used with extreme caution in CHILDREN younger than 16 years; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Quinine Hydrochloride Hoei while you are pregnant. Quinine Hydrochloride Hoei is found in breast milk. If you are or will be breast-feeding while you take Quinine Hydrochloride Hoei, check with your doctor. Discuss any possible risks to your baby.
Quinine Hydrochloride Hoei contraindications
Contraindication can be described as a special circumstance or a disease or a condition wherein you are not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can be dangerous and life threatening as well. When a procedure should not be combined with other procedure or when a medicine cannot be taken with another medicine, it is called Relative contraindication. Contraindications should be taken seriously as they are based on the relative clinical experience of health care providers or from proven research findings.
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Quinine Hydrochloride Hoei Sulfate Capsules are contraindicated in patients with the following:
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Prolonged QT interval. One case of a fatal ventricular arrhythmia was reported in an elderly patient with a prolonged QT interval at baseline, who received Quinine Hydrochloride Hoei sulfate intravenously for P. falciparum malaria.
Hemolysis can occur in patients with G6PD deficiency receiving Quinine Hydrochloride Hoei.
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Known hypersensitivity reactions to Quinine Hydrochloride Hoei.
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These include, but are not limited to, the following :
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Thrombocytopenia
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Idiopathic thrombocytopenia purpura (ITP) and Thrombotic thrombocytopenic purpura (TTP)
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Hemolytic uremic syndrome (HUS)
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Blackwater fever (acute intravascular hemolysis, hemoglobinuria, and hemoglobinemia)
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Known hypersensitivity to mefloquine or quinidine: cross-sensitivity to Quinine Hydrochloride Hoei has been documented.
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Myasthenia gravis. Quinine Hydrochloride Hoei has neuromuscular blocking activity, and may exacerbate muscle weakness.
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Optic neuritis. Quinine Hydrochloride Hoei may exacerbate active optic neuritis.
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References
DailyMed. "QUININE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
European Chemicals Agency - ECHA. "Quinine sulphate: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
The results of a survey conducted on ndrugs.com for Quinine Hydrochloride Hoei are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Quinine Hydrochloride Hoei. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.
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