Relaxid Uses

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Relaxid indications

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Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout), degenerative and chronic inflammatory diseases of musculoskeletal system (osteochondrosis, osteoarthritis, periartropatii), post-traumatic inflammation of soft tissue and musculoskeletal system (sprains, bruises). Pain in the spine, neuralgia, myalgia, arthralgia, pain and inflammation after surgery or injury, pain in gout, migraine, algomenorrhea, pain with Bursitis, proctitis, colic (biliary and renal), pain in infectious and inflammatory diseases of ENT organs.

For local use: the inhibition of miosis during surgery for cataract prevention of cystoid macular edema associated with removal and lens implantation, inflammatory eye non-infectious nature, post-traumatic inflammation in penetrating and nonpenetrating wound of the eyeball.

Relaxid description

Relaxid: Each tablet contains Ibuprofen (Relaxid) 300 mg and Paracetamol (Relaxid) 325 mg.

Relaxid Kid: Each dispersible tablet contains Ibuprofen (Relaxid) 100 mg and Paracetamol (Relaxid) 125 mg. Colour: Tartrazine.

Relaxid Forte: Each tablet contains Ibuprofen (Relaxid) 400 mg and Paracetamol (Relaxid) 500 mg.

Relaxid dosage

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For oral use for adult single dose is 25-50 mg 2-3 times / 24 h. Frequency of admission depends on the dosage form employed, the severity of the disease and is 1-3 times / 24 h, rectally - 1 times / 24 h, for the treatment of acute conditions or the exacerbation of chronic edema use intramuscular in dose of 75 mg.

For children older than 6 years and adolescents daily dose is 2 mg / kg.

Topical applied at a dose of 2-4 g (depending on the size of painful area) on the affected area 3-4 times / 24 h.

When used in ophthalmology frequency and duration of administration are determined individually.

The maximum oral daily dose for adults is 150 mg.

Relaxid interactions

Concurrent use of Phenobarbital, Phenytoin, rifampin or ephedrine may enhance the metabolism of corticosteroids, reducing their therapeutic effects.

Patients receiving both a corticosteroid an estrogen should be observed for excessive corticosteroid effects.

Concurrent use of corticosteroids with potassium-depleting diuretics may enhance

Hypokalemia with cardiac glycosides may enhance the possibility of arrhythmias or digitalis toxicity associated with hypokalemia. Corticosteroids may enhance the potassium depletion caused by amphotericin B. In all patients taking any of these drug therapy combinations, serum electrolyte determinations, particularly potassium levels should be monitored closely.

Concurrent use of corticosteroids with coumarin-type anticoagulants may increase or decrease the anticoagulant effects possibly requiring adjustment in dosage.

Combined effects of non-steroidal anti-inflammatory drugs or alcohol with glucocorticosteroids may result in an increased occurrence or increased severity of gastrointestinal ulceration.

Corticosteroids may decrease blood salicylate concentrations. Acetylsalicylic acid should be used cautiously in conjunction with corticosteroids in hypoprothrombinemia.

Dosage adjustments of an antidiabetic drug may be necessary when corticosteroids are given to diabetics.

Concomitant glucocorticosteroid therapy may inhibit the response to somatotropin.

Laboratory test interactions: corticosteroids may affect the nitroblue tetrazolium test for bacterial infection and produce false negative results.

Relaxid side effects

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Ibuprofen (Relaxid): Cardiovascular System: Tachycardia, flushing, increase in blood pressure.

Central Nervous System: Confusion, hallucinations, mental depression, peripheral neuropathy, tinnitus, drowsiness, insomnia.

Gastrointestinal System: Epigastric pain or discomfort, gastritis, hematemesis, GI perforation, GI ulceration.

Dermatological: Allergic dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Renal: Hematuria, cystitis, renal impairment or failure, polyuria, fluid retention/oedema, acute renal failure, interstitial nephritis, nephrotic syndrome.

Hematological: Agranulocytosis, anaemia, aplastic anaemia, eosinophilia, hemolytic anaemia, leukopenia, thrombocytopenia.

Hypersensitivity Reactions: Anginitis, angioedema, bronchospastic allergic reactions, allergic rhinitis, serum sickness-like reaction, systemic lupus erythematosus, aseptic meningitis.

Ophthalmic:

Amblyopia, blurred or double vision, conjunctivitis, dry irritated or swollen eyes, scotoma.

Oral:

Aphthous stomatitis, gingival ulcerations.

Ear, Nose and Throat: Decreased hearing or any change in hearing, epistaxis.

Hepatic Effect: Hepatitis.

Pancreatic Effect: Pancreatitis.

Paracetamol (Relaxid): Gastrointestinal System: Nausea, vomiting, stomach pain or cramps, diarrhoea, loss of appetite, hepatotoxicity, hepatic failure, hepatic encephalopathy, GIT bleeding, pancreatitis.

Central Nervous System: Convulsions, respiratory depression, cerebral oedema, coma.

Haematological: Leucopenia, thrombocytopenia, neutropenia, pancytopenia, agranulocytosis, disseminated intravascular coagulation.

Metabolic: Hypoglycaemia, metabolic acidosis.

Cardiovascular System: Cardiac arrhythmias, cardiovascular collapse.

Renal System: Renal tubular necrosis, renal failure.

Dermatological: Skin rashes and other allergic reactions. The rash is usually erythematous or urticarial but sometimes more serious and may be accompanied by fever and mucosal lesions.

Relaxid contraindications

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Relaxid is contraindicated in patients with the following conditions: History of severe allergic reaction eg, anaphylaxis or angioedema induced by aspirin or other NSAIDs. Because of the possibility of cross-sensitivity due to structural relationships which exist among non-steroidal anti-inflammatory medicines, acute allergic reactions are likely to occur in patients who have exhibited allergic reactions to these compounds.

Patients sensitive to any of the ingredients.

Aspirin-induced nasal polyps associated with bronchospasm (high risk of severe allergic reactions because of cross-sensitivity).

Active peptic ulceration.

Severe renal function impairment.

Active ingredient matches for Relaxid:

Ibuprofen/paracetamol in Philippines.


List of Relaxid substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Regalam -C Caffeine 65mg, Ibuprofen400mg, Paracetamol 500mg TAB / 10$ 0.19
Renofen Ibuprofen 400mg, Paracetamol325mg TAB / 15$ 0.14
15's$ 0.13
Renofen Ibuprofen 400 mg, paracetamol325 mg. TAB / 15$ 0.14
RENOFEN 400 MG/325 MG TABLET 1 strip / 15 tablets each (Indoco Remedies Ltd)$ 0.16
Renofen 400 mg/325 mg Tablet (Indoco Remedies Ltd)$ 0.01
Restolax 100's (Eurohealth)
Restolax Forte 10's
Restolax Forte 120's$ 11.48
Restolax Forte tab 10's (Lloyd)
Restolax Forte tab 120's (Lloyd)
Restolax tab 10's (Lloyd)
Restolax tab 100's (Lloyd)
Riflam Paracetamol 250mg, Ibuprofen20mg, Diclofenac Sodium 50mg TAB / 20x10$ 4.82
Riflam Paracetamol 250mg, Ibuprofen20mg, Diclofenac Sodium 50mg TAB / 20x10$ 4.82
RUBIGESIC P 400MG/325MG TABLET 1 strip / 10 tablets each (Bevit Pharmaceuticals Ltd)$ 0.48
Rubigesic P 400 mg/325 mg Tablet (Bevit Pharmaceuticals Ltd)$ 0.05
Rumagesic Paracetamol 325mg, Ibuprofen400mg TAB / 20x10$ 2.89
Rumagesic Paracetamol 325mg, Ibuprofen400mg TAB / 20x10$ 2.89
RUMAGESIC 400MG/325MG TABLET 1 strip / 10 tablets each (Numed)$ 0.18
RUMAGESIC PLUS 400 MG/325 MG TABLET 1 strip / 10 tablets each (Numed)$ 0.36
Rumagesic 400mg/325mg Tablet (Numed)$ 0.02
Rumagesic Plus 400 mg/325 mg Tablet (Numed)$ 0.04
10's (Medispan)$ 0.08
Rupar Ibuprofen 400 mg, paracetamol325 mg. TAB / 10 (Medispan)$ 0.08
RUPAR 400MG/325MG TABLET 1 strip / 10 tablets each (Medispan)$ 0.12
RUPAR tab 10's (Medispan)$ 0.08
Rupar Ibuprofen 400 mg, paracetamol325 mg. TAB / 10 (Medispan)$ 0.08
Rupar 400 mg/325 mg Tablet (Medispan)$ 0.01
RUPAR 650MG TABLET 1 strip / 10 tablets each (Medispan Ltd)$ 0.24
RUPAR JUNIOR 400MG/325MG SYRUP 1 bottle / 60 ML syrup each (Medispan Ltd)$ 0.39
Rupar Junior 250mg Syrup (Medispan Ltd)$ 0.39
RUPAR KID DROPS 1 packet / 30 ML drop each (Medispan Ltd)$ 0.30
Rupar Kid Drop (Medispan Ltd)$ 0.30
RUTEK P 300 MG/500 MG TABLET 1 strip / 10 tablets each (Zuventus Healthcare Ltd)$ 0.84
Selxan 100's (Prosel)$ 12.78
SIMULTIN P 100MG/162.5MG SUSPENSION 1 bottle / 60 ML suspension each (Dales Pharmaceuticals Ltd)$ 0.17
Simultin P 100 mg/162.5 mg Suspension (Dales Pharmaceuticals Ltd)$ 0.17
Skelan 220 mg x 100's (Amherst Lab)$ 0.20
Skelan 550 mg x 100's (Amherst Lab)$ 0.39

References

  1. DailyMed. "IBUPROFEN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "ibuprofen". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "ibuprofen". http://www.drugbank.ca/drugs/DB01050 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Relaxid are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Relaxid. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

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Consumer reported price estimates

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7 consumers reported age

Users%
6-152
28.6%
30-452
28.6%
16-292
28.6%
46-601
14.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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