Rhea Nicotinic Acid Side effects

What is the dose of your medication?

Side effects of Rhea Nicotinic Acid in details

A side effect of any drug can be defined as the unwanted or undesired effect produced by the drug. The side effect can be major or in few medications minor that can be ignored. Side effects not only vary from drug to drug, but it also depends on the dose of the drug, the individual sensitivity of the person, brand or company which manufactures it. If side effects overweigh the actual effect of the medicine, it may be difficult to convince the patient to take the drug. Few patients get specific side effects to specific drugs; in that case, a doctor replaces the drug with another. If you feel any side effect and it troubles you, do not forget to share with your healthcare practitioner.

Flush: In the placebo-controlled clinical trials, flushing episodes (ie, feeling hot, erythema, pruritus and/or paresthesia) were the most common treatment-emergent adverse events for Niaspan (reported by 88% of patients). In these studies, <6% of Niaspan patients discontinued due to flushing.

In comparisons of immediate-release (IR) Rhea Nicotinic Acid and Niaspan, although the number of patients who flushed was similar, fewer flushing episodes were reported by patients who received Niaspan. Following 4 weeks of maintenance therapy with Niaspan at daily doses of 1,500 mg, the frequency of flushing over the 4-week period averaged 1.88 events/patient.

Flushing reactions generally occur during early treatment and the dose titration phase. They are thought to be mediated by the release of prostaglandin D2 and tolerance to flushing usually develops over the course of several weeks.

Spontaneous reports suggest that in rare cases, flushing may be more severe and accompanied by symptoms of dizziness, tachycardia, palpitations, dyspnoea, sweating, burning sensation, skin burning sensation, chills and/or oedema, which in rare cases may lead to syncope. Medical treatment should be administered as necessary.

Hypersensitivity Reactions: Hypersensitivity reactions have been reported very rarely. These may be characterized by symptoms eg, generalized exanthema, flush, urticaria, vesiculobullous rash, angioedema, laryngospasm, dyspnoea, hypotension and circulatory collapse. Medical treatment should be administered as necessary.

The following adverse reactions have been observed in clinical studies or in routine patient management, in patients receiving the recommended daily maintenance doses (1,000, 1,500 and 2,000 mg) of Niaspan. They are presented by system organ class and frequency grouping (very common ≥1/10; common ≥1/100, <1/10; uncommon ≥1/1,000, <1/100; rare ≥1/10,000, <1/1,000; very rare <1/10,000, including isolated reports).

In general, the incidence of adverse reactions was higher in women compared to men.

Post-Marketing Experience: The following adverse reactions have been reported in post-marketing experience with Niaspan. Adverse reactions are presented by system organ class.

Infections and Infestations: Infection.

Metabolism and Nutrition Disorders: Diabetes mellitus.

Blood and Lymphatic System Disorders: Haemorrhage.

Nervous System Disorders: Burning sensation, skin burning sensation.

Eye Disorders: Blurred vision.

Hepatobiliary Disorders: Hepatitis.

Skin and Subcutaneous Tissue Disorders: Skin discoloration.

Rhea Nicotinic Acid contraindications

Contraindication can be described as a special circumstance or a disease or a condition wherein you are not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can be dangerous and life threatening as well. When a procedure should not be combined with other procedure or when a medicine cannot be taken with another medicine, it is called Relative contraindication. Contraindications should be taken seriously as they are based on the relative clinical experience of health care providers or from proven research findings.

Contraindications for Vitamin B3 (Rhea Nicotinic Acid)

Rhea Nicotinic Acid is contraindicated in patients with a known hypersensitivity to any component of this medication; significant or unexplained hepatic dysfunction; active peptic ulcer disease; or arterial bleeding.


  1. DailyMed. "NIACIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DTP/NCI. "nicotinic acid: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
  3. European Chemicals Agency - ECHA. "Nicotinic acid: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).


The results of a survey conducted on ndrugs.com for Rhea Nicotinic Acid are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rhea Nicotinic Acid. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported side effects

No survey data has been collected yet

Consumer reviews

There are no reviews yet. Be the first to write one!

Your name: 
Spam protection:  < Type 2 here

Information checked by Dr. Sachin Kumar, MD Pharmacology

| Privacy Policy
This site does not supply any medicines. It contains prices for information purposes only.
© 2003 - 2022 ndrugs.com All Rights Reserved