What is Rihest?
Rihest is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Rihest is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.
Rihest is also used to treat skin hives and itching in people with chronic skin reactions.
Rihest may also be used for purposes not listed in this medication guide.
Rihest indications
Treatment of seasonal allergic rhinitis, perennial rhinitis, urticaria, allergic dermatologic disorders, angioedema and conjunctivitis. Rihest is generally considered to be ineffective in asthma.
Acute anaphylaxis should be treated with adrenaline; Rihest and corticosteroids are given to prevent relapse.
Rihest is also used to control the pruritus associated with skin disorders eg, atopic eczema.
How should I use Rihest?
Use Rihest orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Rihest orally disintegrating tablets by mouth with or without food.
- Be sure that your hands are completely dry before you handle Rihest orally disintegrating tablets. Use the tablet right away after you remove it from the tablet blister.
- To open the tablet blister, peel back the foil, then gently remove the tablet. Place the tablet on the tongue. The tablet will dissolve quickly. You may take Rihest orally disintegrating tablets with or without water.
- If you miss a dose of Rihest orally disintegrating tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Rihest orally disintegrating tablets.
Uses of Rihest in details
This medication is an antihistamine that treats symptoms such as itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergies. It is also used to relieve itching from hives.
Rihest does not prevent hives or prevent/treat a serious allergic reaction (e.g., anaphylaxis). Therefore, if your doctor has prescribed epinephrine to treat allergic reactions, always carry your epinephrine injector with you. Do not use Rihest in place of your epinephrine.
If you are self-treating with this medication, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist.
Do not use this medication in children younger than 6 years unless directed by the doctor. If you are using the chewable tablets, do not use in children younger than 2 years unless directed by your doctor.
How to use Rihest
If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. If your doctor has prescribed this medication, follow your doctor's directions and the instructions on your prescription label. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth with or without food, usually once a day or as directed by your doctor or the product package. If you are using the chewable tablets, chew each tablet well and swallow. Dosage is based on your age, condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take more of this medication than recommended for your age.
Tell your doctor if your allergy symptoms do not improve after 3 days of treatment or if your hives last more than 6 weeks. Seek immediate medical attention if your condition worsens or you think you have a serious medical problem (e.g., very serious allergic reaction/anaphylaxis).
Rihest description
Rihest competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. In addition to the usual allergic symptoms, the drug also treats irritant cough and nausea, vomiting, and vertigo associated with motion sickness. Rihest's anticholinergic action appears to be due to a central antimuscarinic effect, which also may be responsible for its antiemetic effects, although the exact mechanism is unknown. It also is used commonly to treat drug-induced extrapyramidal symptoms as well as to treat mild cases of Parkinson's disease.
Rihest dosage
Rihest Dosage
Applies to the following strength(s): 10 mg; 5 mg/5 mL; 5 mg
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Allergic Rhinitis
- Urticaria
Usual Pediatric Dose for:
- Allergic Rhinitis
- Urticaria
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Dialysis
Usual Adult Dose for Allergic Rhinitis
10 mg orally once a day
Usual Adult Dose for Urticaria
10 mg orally once a day
Usual Pediatric Dose for Allergic Rhinitis
2 to 5 years: 5 mg orally once a day (syrup)
6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)
Usual Pediatric Dose for Urticaria
2 to 5 years: 5 mg orally once a day (syrup)
6 years or older: 10 mg orally once a day (tablets, capsule, and disintegrating tablets)
Renal Dose Adjustments
CrCl less than 30 mL/min: administer dosage every other day initially
Liver Dose Adjustments
Liver failure: administer dosage every other day initially
Dialysis
Rihest is not significantly removed by hemodialysis, thus supplementary dosing is not required following hemodialysis.
More about Rihest
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 43 Reviews - Add your own review/rating
Consumer resources
- Rihest
- Rihest capsules
- Rihest chewable tablets
- Rihest orally disintegrating tablets
- Rihest syrup
- Other brands: Claritin, Alavert, Wal-itin, Claritin 24 Hour Allergy, More (7) »
Professional resources
- Rihest (AHFS Monograph)
- More (4) »
Related treatment guides
- Allergic Rhinitis
- Urticaria
Rihest interactions
See also:
What other drugs will affect Rihest?
Rihest (10 mg once daily) has been coadministered with therapeutic doses of erythromycin, cimetidine, and ketoconazole in controlled clinical pharmacology studies in adult volunteers. Although increased plasma concentrations (AUC 0-24 hrs) of Rihest and/or descarboethoxyloratadine were observed following coadministration of Rihest with each of these drugs in normal volunteers (n = 24 in each study), there were no clinically relevant changes in the safety profile of Rihest, as assessed by electrocardiographic parameters, clinical laboratory tests, vital signs, and adverse events. There were no significant effects on QTc intervals, and no reports of sedation or syncope. No effects on plasma concentrations of cimetidine or ketoconazole were observed. Plasma concentrations (AUC 0-24 hrs) of erythromycin decreased 15% with coadministration of Rihest relative to that observed with erythromycin alone. The clinical relevance of this difference is unknown. These above findings are summarized in TABLE 1.
| TABLE 1 Effects on Plasma Concentrations (AUC 0-24 hrs) of Rihest and Descarboethoxyloratadine After 10 Days of Coadministration (Rihest 10 mg) in Normal Volunteers | ||
| Rihest | Descarboethoxyloratadine | |
|---|---|---|
| Erythromycin (500 mg q8h) | + 40% | +46% |
| Cimetidine (300 mg qid) | +103% | + 6% |
| Ketoconazole (200 mg q12h) | +307% | +73% |
Rihest side effects
See also:
What are the possible side effects of Rihest?
Applies to Rihest: oral fixed-combination tablets, oral orally disintegrating tablets, oral solution, oral tablets
Side effects include:
Children 2–5 years of age receiving oral solution: Diarrhea, epistaxis, pharyngitis, flu-like symptoms, fatigue, stomatitis, tooth disorder, earache, viral infection, rash.
Children 6–12 years of age receiving oral solution: Nervousness, wheezing, fatigue, hyperkinesia, abdominal pain, conjunctivitis, dysphonia, upper respiratory tract infection.
Adults and children ≥12 years of age receiving conventional or orally disintegrating tablets: Headache, somnolence, fatigue, dry mouth.
Fixed combination Rihest (the active ingredient contained in Rihest Reditab) pseudoephedrine sulfate preparations: Insomnia, dry mouth, headache, somnolence, nervousness, dizziness, fatigue.
Rihest contraindications
See also:
What is the most important information I should know about Rihest?
Do NOT use Rihest if:
you are allergic to any ingredient in Rihest
Contact your doctor or health care provider right away if any of these apply to you.
Active ingredient matches for Rihest:
Loratadine in Indonesia.
| Unit description / dosage (Manufacturer) | Price, USD |
| Rihest 10 mg x 10's | $ 34.72 |
| Rihest 5 mg/5 mL x 1's | $ 2.11 |
List of Rihest substitutes (brand and generic names): | |
| Ridertin (Vietnam) | |
| Ridertin 10 mg x 3 Blister x 10 Tablet | |
| Rinal (Peru) | |
| Rinaler (Peru) | |
| Rinalor (Peru) | |
| Rinard (Mexico) | |
| Rinconad (Vietnam) | |
| Rinconad 10 mg x 2 Blister x 10 Tablet | |
| Rinityn (Hong Kong, Philippines, Singapore) | |
| Rinityn 10 mg x 2 x 10's (Hovid) | |
| Rinityn 10 mg x 10 x 10's (Hovid) | |
| Rinityn 10 mg x 100's (Hovid) | $ 46.67 |
| Rinityn 10 mg x 1000's (Hovid) | |
| Rinityn 頑敏清 (Hongkong) | |
| Rinityn tab 10 mg 10 x 10's (Hovid) | |
| Rinityn tab 10 mg 2 x 10's (Hovid) | |
| Rinolan (Bosnia & Herzegowina, Croatia (Hrvatska), Estonia, Latvia, Lithuania, Romania, Slovenia) | |
| Ristotadin (Greece) | |
| RiteMED Loratadine (Philippines) | |
| RiteMED Loratadine tab 10 mg 10's (RiteMED) | |
| Ritin (Turkey) | |
| Rityne (Thailand) | |
| Rityne 10 mg x 10 x 10's (Osoth Interlab) | |
| Rityne tab 10 mg 10 x 10's (Osoth Interlab) | |
| Rodakin (Mexico) | |
| Rodamine (Taiwan) | |
| Rodamine 1 mg x 30 mL | |
| Rohist (South Africa) | |
| Rokadin (Mexico) | |
| Roletra (Bulgaria, Czech Republic, Hungary, India, Oman, Peru, Romania, Thailand, Venezuela) | |
| Roletra 10mg TAB / 10 (Ranbaxy) | $ 0.28 |
| Roletra 5mg/mL SYR / 30ml (Ranbaxy) | $ 0.20 |
| Roletra 10 mg x 10 x 10's (Ranbaxy) | |
| 10 mg x 10's (Ranbaxy) | $ 0.28 |
| 5 mg x 5 mL x 30ml (Ranbaxy) | $ 0.20 |
| Roletra 10 mg x 100's (Ranbaxy) | |
| Roletra tab 10 mg 10 x 10's (Ranbaxy) | |
| ROLETRA tab 10 mg x 10's (Ranbaxy) | $ 0.28 |
| ROLETRA syr 5 mg x 5 mL x 30ml (Ranbaxy) | $ 0.20 |
| Roletra MDT (Malaysia) | |
| Roletra MDT 10 mg x 10 x 10's | |
| Roletra- D | |
| Roletra- D Loratadine 10mg, Pseudoephedrine Sulphate 180mg FC-TAB / 10 | $ 0.36 |
| Ronpect (South Korea) | |
| Rotadin (Poland) | |
| Rotifar (Malaysia) | |
| Rotifar 10 mg x 500's (Duopharma) | |
| Rui Fu (China) | |
| Run Lai (China) | |
| Rupton (Belgium, Luxembourg) | |
| Rupton 10mg (Luxembourg) | |
| Safetin (Myanmar) | |
| Salora (Bangladesh) | |
See 1851 substitutes for Rihest | |
References
- DailyMed. "LORATADINE; PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "loratadine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "loratadine". http://www.drugbank.ca/drugs/DB00455 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Rihest are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rihest. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
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Information checked by Dr. Sachin Kumar, MD Pharmacology
