Rin Up Uses

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What is Rin Up?

Rin Up ophthalmic causes constriction of blood vessels in the eyes. It also enlarges the pupils, reduces the production of fluid in the eyes, and increases the amount of fluid that drains from the eyes.

Rin Up ophthalmic available over-the-counter is used to relieve redness, burning, irritation, and dryness of the eye caused by wind, sun, and other minor irritants. Prescription-strength Rin Up ophthalmic is used to constrict blood vessels in the eye and to dilate (make bigger) the pupil for conditions such as glaucoma, before surgery, and before eye examinations.

Rin Up ophthalmic may also be used for purposes other than those listed in this medication guide.

Rin Up indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Rin Up is used for the temporary relief of stuffy nose, sinus, and ear symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). This medication works by decreasing swelling in the nose and ears, thereby lessening discomfort and making it easier to breathe.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

How should I use Rin Up?

Use Rin Up drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Rin Up drops is for use in the eye only. Avoid contact with the nose or mouth.
  • To use Rin Up drops, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.
  • Do not wear contact lenses while you are using Rin Up drops. Sterilize contact lenses according to the manufacturer's directions and check with your doctor before using them.
  • Do not use Rin Up drops if it is brown or contains particles.
  • If you miss a dose of Rin Up drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Rin Up drops.

Uses of Rin Up in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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This combination medication is used to temporarily treat cough and runny/stuffy nose (nasal congestion) caused by infections (such as the common cold), allergies (such as hay fever), and other breathing illnesses. This product is usually not used for ongoing cough from smoking or long-term breathing problems (such as chronic bronchitis, emphysema) unless directed by your doctor. Guaifenesin is an expectorant. It works by thinning and loosening mucus in the airways, clearing congestion, and making breathing easier. Rin Up is a decongestant (sympathomimetic). It reduces nasal congestion by narrowing the blood vessels in the nose.

If you are self-treating with this medication, it is important to read the package instructions carefully before you start using this product to be sure it is right for you.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Rin Up

Take this medication by mouth with or without food, as directed by your doctor. If you are self-treating, follow all directions on the product package. To prevent trouble sleeping, do not take this medication close to bedtime. If you are uncertain about any of the information, ask your doctor or pharmacist.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed.

Guaifenesin may have a bitter taste. Swallow capsules and tablets whole. Scored tablets may be split for lower doses. Chewable tablets may be swallowed whole or chewed.

Drink plenty of fluids while taking this medication. Fluids will help to break up mucus and clear congestion.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Tell your doctor if your condition is accompanied by fever, severe sore throat, rash, persistent headache, or if it persists, returns, or worsens after 7 days. These may be signs of a serious medical problem. Seek immediate medical attention if you think you may have a serious medical problem.

Rin Up description

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Rin Up is a sympathomimetic amine that acts predominantly on α-adrenergic receptors. It is mainly used to treat nasal congestion, but may also be useful in treating hypotension and shock, hypotension during spinal anaesthesia, prolongation of spinal anaesthesia, paroxysmal supraventricular tachycardia, symptomatic relief of external or internal hemorrhoids, and to increase blood pressure as an aid in the diagnosis of heart murmurs.

Rin Up dosage

Prolonged exposure to air or strong light may cause oxidation and discoloration. Do not use if solution is brown or contains a precipitate.

Vasoconstriction and Pupil Dilatation

Rin Up (Rin Up ophthalmic solution) hydrochloride 10 percent ophthalmic solutions are especially useful when rapid and powerful dilatation of the pupil and reduction of congestion in the capillary bed are desired. A drop of a suitable topical anesthetic may be applied, followed in a few minutes by 1 drop of the Rin Up (Rin Up ophthalmic solution) hydrochloride 10 percent ophthalmic solutions on the upper limbus. The anesthetic prevents stinging and consequent dilution of the solution by lacrimation. It may occasionally be necessary to repeat the instillation after one hour, again preceded by the use of the topical anesthetic.

Uveitis: Posterior Synechiae

Rin Up (Rin Up ophthalmic solution) hydrochloride 10 percent ophthalmic solutions may be used in patients with uveitis when synechiae are present or may develop. The formation of synechiae may be prevented by the use of the 10 percent ophthalmic solutions and atropine to produce wide dilatation of the pupil. It should be emphasized, however, that the vasoconstrictor effect of Rin Up (Rin Up ophthalmic solution) hydrochloride may be antagonistic to the increase of local blood flow in uveal infection.

To free recently formed posterior synechiae, 1 drop of the 10 percent ophthalmic solutions may be applied to the upper surface of the cornea. On the following day, treatment may be continued if necessary. In the interim, hot compresses should be applied for five or ten minutes three times a day, with 1 drop of a 1 or 2 percent solution of atropine sulfate before and after each series of compresses.

Glaucoma

In certain patients with glaucoma, temporary reduction of intraocular tension may be attained by producing vasoconstriction of the intraocular vessels; this may be accomplished by placing 1 drop of the 10 percent ophthalmic solutions on the upper surface of the cornea. This treatment may be repeated as often as necessary.

Rin Up (Rin Up ophthalmic solution) hydrochloride may be used with miotics in patients with wide angle glaucoma. It reduces the difficulties experienced by the patient because of the small field produced by miosis, and still it permits and often supports the effect of the miotic in lowering the intraocular pressure. Hence, there may be marked improvement in visual acuity after using Rin Up (Rin Up ophthalmic solution) hydrochloride in conjunction with miotic drugs.

Surgery

When a short-acting mydriatic is needed for wide dilatation of the pupil before intraocular surgery, the 10 percent ophthalmic solutions or 2.5 percent ophthalmic solution may be applied topically from 30 to 60 minutes before the operation.

Refraction

Prior to determination of refractive errors, Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent ophthalmic solution may be used effectively with homatropine hydrobromide, atropine sulfate, or a combination of homatropine and cocaine hydrochloride.

For adults, a drop of the preferred cycloplegic is placed in each eye, followed in five minutes by 1 drop of Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent ophthalmic solution and in ten minutes by another drop of the cycloplegic. In 50 to 60 minutes, the eyes are ready for refraction.

For children, a drop of atropine sulfate 1 percent is placed in each eye, followed in 10 to 15 minutes by 1 drop of Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent ophthalmic solution and in five to ten minutes by a second drop of atropine sulfate 1 percent. In one to two hours, the eyes are ready for refraction.

For a “one application method,” Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent ophthalmic solution may be combined with a cycloplegic to elicit synergistic action. The additive effect varies depending on the patient. Therefore, when using a “one application method,” it may be desirable to increase the concentration of the cycloplegic.

Ophthalmoscopic Examination

One drop of Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent ophthalmic solution is placed in each eye. Sufficient mydriasis to permit examination is produced in 15 to 30 minutes. Dilatation lasts from one to three hours.

Diagnostic Procedures

Provocative Test for Angle Block in Patients with Glaucoma: The 2.5 percent ophthalmic solution may be used as a provocative test when latent increased intraocular pressure is suspected. Tension is measured before application of Rin Up (Rin Up ophthalmic solution) hydrochloride and again after dilatation. A 3 to 5 mm of mercury rise in pressure suggests the presence of angle block in patients with glaucoma; however, failure to obtain such a rise does not preclude the presence of glaucoma from other causes.

Shadow Test (Retinoscopy): When dilatation of the pupil without cycloplegic action is desired for the shadow test, the 2.5 percent ophthalmic solution may be used alone.

Blanching Test: One or 2 drops of the 2.5 percent ophthalmic solution should be applied to the injected eye. After five minutes, examine for perilimbal blanching. If blanching occurs, the congestion is superficial and probably does not indicate iritis.

How supplied

In Mono-Drop ® plastic dropper bottle: Low surface tension solutions

2.5 percent ophthalmic solution - Rin Up (Rin Up ophthalmic solution) hydrochloride 2.5 percent in a sterile, isotonic, buffered, low surface tension vehicle with sodium phosphate, sodium biphosphate, boric acid, and, as antiseptic preservative, benzalkonium chloride, NF, 1:7500. The pH is adjusted with phosphoric acid or sodium hydroxide. Bottles of 15 mL (NDC 0024-1358-01).

10 percent ophthalmic solution- Rin Up (Rin Up ophthalmic solution) hydrochloride 10 percent in a sterile, buffered, low surface tension vehicle with sodium phosphate, sodium biphosphate, and, as antiseptic preservative, benzalkonium chloride 1:10,000. The pH is adjusted with phosphoric acid or sodium hydroxide. Bottles of 5 mL (NDC 0024-1359-01).

Viscous solution

10 percent ophthalmic solution- Rin Up (Rin Up ophthalmic solution) hydrochloride 10 percent in a sterile, buffered, viscous vehicle with sodium phosphate, sodium biphosphate, methylcellulose, and, as antiseptic preservative, benzalkonium chloride 1:10,000. The pH is adjusted with phosphoric acid or sodium hydroxide. Bottles of 5 mL (NDC 0024-1362-01).

Store at 25° C (77° F); excursions permitted to 15° - 30° C (59° - 86° F)

Manufactured for Sanofi-Synthelabo Inc. New York, NY 10016 by Abbott Laboratories North Chicago, IL 60064. Revised September 1999. FDA revision date: n/a

Rin Up interactions

See also:
What other drugs will affect Rin Up?

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The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include: other decongestants (taken by mouth or sprayed into the nose), tricyclic antidepressants (such as nortriptyline, amitriptyline), MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine).

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.

Rin Up may decrease the effectiveness of some blood pressure medications (such as beta blockers, reserpine, guanethidine, methyldopa, mecamylamine).

Guaifenesin and Rin Up are available in both prescription and nonprescription products. Check the labels of all your medications to make sure you are not taking more than one product containing guaifenesin or Rin Up.

Guaifenesin can affect the results of certain lab tests (such as urine levels of certain acids). Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Rin Up side effects

See also:
What are the possible side effects of Rin Up?

Applies to Rin Up: intravenous solution

In addition to its needed effects, some unwanted effects may be caused by Rin Up (the active ingredient contained in Rin Up). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking Rin Up, check with your doctor or nurse immediately:

Incidence not known:

  • Blurred vision
  • chest pain or discomfort
  • difficult or labored breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • headache
  • nausea or vomiting
  • nervousness
  • pain in the shoulders, arms, jaw, or neck
  • pounding in the ears
  • sweating
  • tightness in the chest
  • unusual tiredness

If any of the following symptoms of overdose occur while taking Rin Up, get emergency help immediately:

Symptoms of overdose:

  • Feeling of fullness in the head
  • pounding or rapid pulse
  • tingling in the arms or legs
  • vomiting

Minor Side Effects

Some of the side effects that can occur with Rin Up may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known:

  • Heartburn
  • itching skin
  • nausea
  • pain in the neck
  • pain or discomfort in chest, upper stomach, or throat

Rin Up contraindications

See also:
What is the most important information I should know about Rin Up?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

If you wear contact lenses, remove them before applying Rin Up ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Rin Up ophthalmic may contains preservative (benzalkonium chloride), which may cause discoloration of contact lenses.

Do not use Rin Up ophthalmic more often or continuously for longer than 48 to 72 hours without consulting a doctor. Chronic use of this medication may damage the blood vessels (veins and arteries) in the eyes. Consult a doctor if your symptoms do not improve or appear to worsen.

Use caution when driving, operating machinery, or performing other hazardous activities. Rin Up ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.

Active ingredient matches for Rin Up:

Phenylephrine in Spain.

Phenylephrine hydrochloride in Spain.


List of Rin Up substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
RIMYCOLD SYR syr 60ml (Ventus)$ 0.56
Rinofast Paracetamol 650 mg, phenylephrine hydrochloride 5mg, chlorpheniramine maleate 2mg, caffeine anhydrous 30 mg. TAB / 10 (Shield)$ 0.37
RINOFAST 5MG/2MG DROPS 1 packet / 15 ML drop each (Shield)$ 0.60
RINOFAST 5MG/2MG SYRUP 1 bottle / 60 ML syrup each (Shield)$ 0.60
RINOFAST coated tab 10's (Shield)$ 0.37
Rinofast 2 mg/5 mg Drop (Shield)$ 0.60
Rinofast 2 mg/5 mg Syrup (Shield)$ 0.60
Rinofast Tablet (Shield)$ 0.04
Rinofast SYR Phenylephrine hydrochloride 5mg, chlorpheniramine maleate 2mg/5 mL. SYR / 60ml (Shield)$ 0.48
RINOFAST SYR syr 60ml (Shield)$ 0.48
Saczine-Cold Cetirizine 5 mg, phenylephrine10 mg, paracetamol 500 mg, caffeine 30 mg. TAB / 10 (Sac Pharma)$ 0.40
SACZINE-COLD tab 10's (Sac Pharma)$ 0.40
SALIN P DROP 1 packet / 1 ML drop each (West-Coast Pharmaceutical Works Ltd)$ 0.43
Sensicold Phenylephrine HCl 2.5mg, Chlorpheniramine Maleate 1mg, Paracetamol 125mg SYR / 60ml (Docventures)$ 0.60
SENSICOLD syr 60ml (Docventures)$ 0.60
10's (Samruddhi (Centaur Pharmaceuticals))$ 0.64
Sinarest Levo 10+2.5 Tablet (Samruddhi (Centaur Pharmaceuticals))$ 0.06
Sinarest Levo Levocetirizine 2.5 mg, Phenylephrine 10 mg. TAB / 10 (Samruddhi (Centaur Pharmaceuticals))$ 0.64
SINAREST LEVO TABLET 1 strip / 10 tablets each (Samruddhi (Centaur Pharmaceuticals))$ 0.86
SINAREST LEVO tab 10's (Samruddhi (Centaur Pharmaceuticals))$ 0.64
Sinarest Levo Levocetirizine 2.5 mg, Phenylephrine 10 mg. TAB / 10 (Samruddhi (Centaur Pharmaceuticals))$ 0.64
Sinarest Levo Tablet (Samruddhi (Centaur Pharmaceuticals))$ 0.10
15ml (Centaur (Shashvatam))$ 0.52
Sinarest-Af Dps Phenylephrine hydrochloride2.5 mg, Chlorpheniraminemaleate 1 mg/1 mL. DPS / 15ml (Centaur (Shashvatam))$ 0.52
SINAREST-AF DPS oral drops 15ml (Centaur (Shashvatam))$ 0.57
Sinarest-Af Dps Phenylephrine hydrochloride2.5 mg, Chlorpheniraminemaleate 1 mg/1 mL. DPS / 15ml (Centaur (Shashvatam))$ 0.52
Sinarest-PD Syr Paracetamol 125 mg, phenylephrine hydrochloride2.5 mg, chlorpheniraminemaleate 1 mg, sodium citrate60 mg, menthol 0.5 mg/5 mL. SYR / 60ml (Centaur)$ 0.49
SINAREST-PD SYR syr 60ml (Centaur)$ 0.49
Sinucold Cetirizine 5 mg, paracetamol325 mg, phenylephrine 5 mg. TAB / 10 (Intecare)$ 0.67
Sinucold Cetirizine 2.5 mg, paracetamol12.5 mg, phenylephrine 5 mg. O-SUSP / 60ml (Intecare)$ 0.56
SINUCOLD tab 10's (Intecare)$ 0.67
SINUCOLD oral susp 60ml (Intecare)$ 0.56
Sinurhon Tablet (Leben Laboratories Pvt. Ltd.)$ 0.53
Spray; Nasal; Phenylephrine (Spirig)

References

  1. PubChem. "phenylephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "phenylephrine". http://www.drugbank.ca/drugs/DB00388 (accessed September 17, 2018).
  3. MeSH. "Cardiotonic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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