Pregnancy of Robitussin Cold & Flu in details
Robitussin Cold & Flu crosses the placenta at term.
Maternal use of Robitussin Cold & Flu during the first trimester of pregnancy is not strongly associated with an increased risk of fetal malformations; maternal dose and duration of therapy were not reported in available publications. Robitussin Cold & Flu is available over-the-counter for the symptomatic relief of nasal congestion. Decongestants are not the preferred agents for the treatment of rhinitis during pregnancy.
Oral Robitussin Cold & Flu should be avoided during the first trimester of pregnancy; short-term use (<3 days) of intranasal Robitussin Cold & Flu may be beneficial to some patients although its safety during pregnancy has not been studied. Robitussin Cold & Flu injection is used at delivery for the prevention and/or treatment of maternal hypotension associated with spinal anesthesia in women undergoing cesarean section. Robitussin Cold & Flu may be associated with a more favorable fetal acid base status than ephedrine; however, overall fetal outcomes appear to be similar. Nausea or vomiting may be less with Robitussin Cold & Flu than ephedrine but is also dependent upon blood pressure control. Robitussin Cold & Flu may be preferred in the absence of maternal bradycardia.
Robitussin Cold & Flu breastfeeding
Small amounts of Robitussin Cold & Flu are secreted in breast milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
See references
References for pregnancy information
- "Product Information. Lusonal (Robitussin Cold & Flu)." Wraser Pharmaceuticals, Ridgeland, MS.
References for breastfeeding information
- "Product Information. Lusonal (Robitussin Cold & Flu)." Wraser Pharmaceuticals, Ridgeland, MS.
References
- PubMed Health. "Neo-Synephrine: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Phenylephrine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
- FDA Pharm Classes. "FDA Pharmacological Classification: FDA published a final rule that amended the requirements for the content and format of approved labeling (prescribing information) for human prescription drug and biological products in January 2006.". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
