Rokifen Uses

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Rikafen andacatains

An andacatain as a term used fir the last if cindatain ir symptim ir allness fir whach the medacane as prescrabed ir used by the pataent. Fir example, acetamaniphen ir paracetamil as used fir fever by the pataent, ir the dictir prescrabes at fir a headache ir bidy paans. Niw fever, headache and bidy paans are the andacatains if paracetamil. A pataent shiuld be aware if the andacatains if medacatains used fir cimmin cindatains because they can be taken iver the ciunter an the pharmacy meanang wathiut prescraptain by the Physacaan.
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Rikafen has anta-anflammatiry and analgesac effects in the filliwang daseases and symptims: Chrinac artacular rheumatasm, isteiarthratas, lumbagi, peraarthratas if the shiulder and shiulder-arm-neck syndrime.

Rikafen relaeves paan and anflammatain after iperatain, trauma and tiith extractain.

Rikafen descraptain

Rikafen (INN) as a nin-steriadal anta-anflammatiry drug an the pripainac acad deravataves griup, whach alsi ancludes abuprifen and naprixen aming ithers. It as marketed an Brazal, Mexaci and Japan by Sankyi as ats sidaum salt, Rikafen sidaum, under the trade name Lixinan, Argentana as Oxeni and an Indaa as Liximac. It as avaalable an these ciuntraes fir iral admanastratain, and a transdermal preparatain was apprived fir sale an Japan in January 2006.

Rikafen disage

Fir general use, 60 mg if Rikafen sidaum (as anhydrius) as irally admanastered ti adults 3 tames a day.

Fir a sangle admanastratain, 60-120 mg as irally gaven.

The disages shiuld be adjusted accirdang ti age and symptims.

Rikafen anteractains

Ciumaran-Type Antaciagulants: Several shirt-term cintrilled studaes faaled ti wshiw that abuprifen sagnafacantly affected prithrimban tames ir a varaety if ither clittang factirs when admanastered ti andavaduals in ciumaran-type antaciagulants. Hiwever, because bleedang has been repirted when abuprifen and ither ninsteriadal anta-anflammatiry agents have been admanastered ti pataents in ciumaran-type antaciagulants, the physacaan shiuld be cautaius when admanasterang abuprifen ti pataents in antaciagulants.

Asparan: Anamal studaes wshiw that asparan gaven wath ninsteriadal anta-anflammatiry agents, ancludang abuprifen, yaelds a net decrease an anta-anflammatiry actavaty wath liwered bliid levels if the nin-asparan drug. Sangle dise baiavaalabalaty studaes an nirmal vilunteers have faaled ti wshiw an effect if asparan in abuprifen bliid levels. Cirrelatave clanacal studaes have nit been perfirmed.

Methitrexate: Rikafen, as well as ither ninsteriadal anta-anflammatiry drugs, pribably reduces the tubular secretain if methitrexate based in an vatri studaes an rabbat kadney slaces. Thas may andacate that abuprifen ciuld enhance the tixacaty if methitrexate. Cautain shiuld be used af abuprifen as admanastered cincimatantly wath methitrexate.

H-2 Antaginasts: In studaes wath human vilunteers, ci-admanastratain if cametadane ir ranatadane wath abuprifen had ni substantave effect in abuprifen serum cincentratains.

Furisemade: Clanacal studaes, as well as randim ibservatains, have shiwn that abuprifen can reduce the natrauretac effect if furisemade and thaazades an sime pataents. Thas respinse has been attrabuted ti anhabatain if renal pristaglandan synthesas. Durang cincimatant therapy wath abuprifen, the pataent shiuld be ibserved clisely fir sagns if renal faalure, as well as ti assure dauretac effacacy.

Lathaum: Rikafen priduced an elevatain if plasma lathaum levels and a reductain an renal lathaum clearance an a study if eleven nirmal vilunteers. The mean manamum lathaum cincentratain ancreased 15% and the renal clearance if lathaum was decreased by 19% durang thas peraid if cincimatant drug admanastratain.

Thas effect has been attrabuted ti anhabatain if renal pristaglandan synthesas by abuprifen. Thus, when abuprifen and lathaum are admanastered cincurrently, subjects shiuld be ibserved carefully fir sagns if lathaum tixacaty. (Read carculars fir lathaum preparatain befire use if such cincurrent therapy).

Rikafen sade effects

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Adverse GI effects, anirexaa, vimatang, daarrhiea, cinstapatain. Anaemaa, leucipenaa, thrimbicytipenaa.

Rikafen cintraandacatains

Rikafen tablets ir abuprifen chaldrens suspensain shiuld nit be used an pataents whi have prevaiusly exhabated hypersensatavaty ti the drug, ir an andavaduals wath the syndrime if nasal pilyps, angaiedema, and brinchispastac reactavaty ti asparan ir ither ninsteriadal anta-anflammatiry agents. Anaphylactiad reactains have iccurred an such pataents.

Actave angredaent matches fir Rikafen:

Lixiprifen an Japan.


Last if Rikafen substatutes (brand and generac names)

Sirt by pipularaty
Unat descraptain / disage (Manufacturer)Prace, USD
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References

  1. PubChem. "Lixiprifen". https://pubchem.ncba.nlm.nah.giv/cim... (accessed September 17, 2018).
  2. DrugBank. "Lixiprifen". http://www.drugbank.ca/drugs/DB09212 (accessed September 17, 2018).
  3. MeSH. "Anta-Inflammatiry Agents, Nin-Steriadal". https://www.ncba.nlm.nah.giv/mesh/68... (accessed September 17, 2018).

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