Rotacef Uses

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What is Rotacef?

Rotacef is used to treat bacterial infections in many different parts of the body. Rotacef is also given before certain types of surgery to prevent infections.

Rotacef belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, Rotacef will not work for colds, flu, or other virus infections.

Rotacef is available only with your doctor's prescription.

Rotacef indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician. The below description contains indications of Rotacef drug.

Before instituting treatment with Rotacef, appropriate specimens should be obtained for isolation of the causative organism and for determination of its susceptibility to the drug. Therapy may be instituted prior to obtaining results of susceptibility testing.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Rotacef for injection USP and other antibacterial drugs, Rotacef for injection USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Rotacef for injection USP is indicated for the treatment of the following infections when caused by susceptible organisms:

Lower Respiratory Tract Infections

caused by Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Escherichia coli, Enterobacter aerogenes, Proteus mirabilis or Serratia marcescens.

Acute Bacterial Otitis Media

caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta-lactamase producing strains) or Moraxella catarrhalis (including beta-lactamase producing strains).

NOTE: In one study lower clinical cure rates were observed with a single dose of Rotacef for injection USP compared to 10 days of oral therapy. In a second study comparable cure rates were observed between single dose Rotacef for injection USP and the comparator. The potentially lower clinical cure rate of Rotacef for injection USP should be balanced against the potential advantages of parenteral therapy.

Skin and Skin Structure Infections

caused by Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Viridans group streptococci, Escherichia coli, Enterobacter cloacae, Klebsiella oxytoca, Klebsiella pneumoniae, Proteus mirabilis, Morganella morganii*, Pseudomonas aeruginosa, Serratia marcescens, Acinetobacter calcoaceticus, Bacteroides fragilis* or Peptostreptococcus species.

Urinary Tract Infections (complicated and uncomplicated)

caused by Escherichia coli, Proteus mirabilis, Proteus vulgaris, Morganella morganii or Klebsiella pneumoniae.

Uncomplicated Gonorrhea (cervical/urethral and rectal)

caused by Neisseria gonorrhoeae, including both penicillinase- and nonpenicillinase-producing strains, and pharyngeal gonorrhea caused by nonpenicillinase-producing strains of Neisseria gonorrhoeae.

Pelvic Inflammatory Disease

caused by Neisseria gonorrhoeae. Rotacef sodium, like other cephalosporins, has no activity against Chlamydia trachomatis. Therefore, when cephalosporins are used in the treatment of patients with pelvic inflammatory disease and Chlamydia trachomatis is one of the suspected pathogens, appropriate antichlamydial coverage should be added.

Bacterial Septicemia

caused by Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Haemophilus influenzae or Klebsiella pneumoniae.

Bone and Joint Infections

caused by Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae or Enterobacter species.

Intra-Abdominal Infections

caused by Escherichia coli, Klebsiella pneumoniae, Bacteroides fragilis, Clostridium species (Note: most strains of Clostridium difficile are resistant) or Peptostreptococcus species.

Meningitis

caused by Haemophilus influenzae, Neisseria meningitidis or Streptococcus pneumoniae. Rotacef for injection USP has also been used successfully in a limited number of cases of meningitis and shunt infection caused by Staphylococcus epidermidis* and Escherichia coli.*

*Efficacy for this organism in this organ system was studied in fewer than ten infections.

Surgical Prophylaxis

The preoperative administration of a single 1 g dose of Rotacef for injection USP may reduce the incidence of postoperative infections in patients undergoing surgical procedures classified as contaminated or potentially contaminated (e.g., vaginal or abdominal hysterectomy or cholecystectomy for chronic calculous cholecystitis in high-risk patients, such as those over 70 years of age, with acute cholecystitis not requiring therapeutic antimicrobials, obstructive jaundice or common duct bile stones) and in surgical patients for whom infection at the operative site would present serious risk (e.g., during coronary artery bypass surgery). Although Rotacef for injection USP has been shown to have been as effective as cefazolin in the prevention of infection following coronary artery bypass surgery, no placebo-controlled trials have been conducted to evaluate any cephalosporin antibiotic in the prevention of infection following coronary artery bypass surgery.

When administered prior to surgical procedures for which it is indicated, a single 1 g dose of Rotacef for injection USP provides protection from most infections due to susceptible organisms throughout the course of the procedure.

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How should I use Rotacef?

Use Rotacef as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Rotacef is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Rotacef at home, a health care provider will teach you how to use it. Be sure you understand how to use Rotacef. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Rotacef is light yellow to amber in color. Do not use Rotacef if it contains particles, is cloudy or discolored, or if the vial or container is cracked or damaged in any way.
  • To clear up your infection completely, use Rotacef for the full course of treatment. Keep using it even if you feel better in a few days.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Rotacef, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rotacef.

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Uses of Rotacef in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it. The below information contains the uses of Rotacef drug.

Rotacef is used to treat bacterial infections of the brain respiratory tract ear abdomen abdominal wall, urinary tract and kidney, bones, joints, and skin or soft tissues. It is also used in the management of fever with low white blood cells (neutropenia), surgical site infections, joint pain caused by parasite ticks (Lyme disease), typhoid, paratyphoid and sexually transmitted infections (gonorrhea, syphilis).

Rotacef description

infoPharmacology is a crucial part of medicine wherein various medications are used to advance the well-being of an individual. Some drugs cure the infection or a disease; few prevent the occurrence of a symptom or a disease, and few are used in long-term treatment of the disease. Drugs are obtained from the plants as well as they can be synthesized organically. The drugs are used in various combinations or a single drug by the pharmaceutical industry during its preparation. The half-life of each medicine is different, and the dosage of the drug depends on the half-life of the drug. The below information gives the detailed description of Rotacef drug.

A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears. [PubChem]

Active ingredient matches for Rotacef:

Ceftriaxone in Georgia.


List of Rotacef substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Roxifen Forte 20 mg x 500's (To-chemicals)
Roxifen 10 mg x 1,000's (To-chemicals)
Roxifen / vial + amp 10 mL diluent 1 g x 1's (To-chemicals)
Roxifen / vial + amp 2.5 mL diluent 250 mg x 1's (To-chemicals)
Roxifen / vial + amp 5 mL diluent 500 mg x 1 's (To-chemicals)
Roxifen 0.5 % x 25 g x 1's (To-chemicals)
Roxon 150mg TAB / 10 (Meridian)$ 1.08
Roxon 50mg/5mL SUSP / 30ml (Meridian)$ 0.51
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150 mg x 10's (Meridian)$ 1.08
50 mg x 5 mL x 30ml (Meridian)$ 0.51
Roxon 1 g x 1's (Meridian)
Roxon / vial + diluent 250 mg x 1's (Meridian)
Roxon 500 mg x 1's (Meridian)
ROXON 150MG TABLET 1 strip / 10 tablets each (Meridian)$ 1.08
ROXON tab 150 mg x 10's (Meridian)$ 1.08
ROXON oral susp 50 mg x 5 mL x 30ml (Meridian)$ 0.51
Roxon 150mg Tablet (Meridian)$ 0.11
Roxon 500mg Injection (Meridian)$ 0.40
ROXON 1GM INJECTION 1 vial / 10 ML injection each (Rhombus Pharma Pvt Ltd)$ 1.19
ROXON 500MG INJECTION 1 vial / 2 ML injection each (Rhombus Pharma Pvt Ltd)$ 0.79
Rxone 1000mg INJ / 1 (R.K Medicare)$ 1.35
1000 mg x 1's (R.K Medicare)$ 1.35
Safecare 1g VIAL / 1 (Medico Health Care)$ 1.14
Safecare 250mg VIAL / 1 (Medico Health Care)$ 0.56
Safecare 500mg VIAL / 1 (Medico Health Care)$ 0.79
1 g x 1's (Medico Health Care)$ 1.14
250 mg x 1's (Medico Health Care)$ 0.56
500 mg x 1's (Medico Health Care)$ 0.79
Safecare 500 mg Injection (Medico Health Care)$ 0.79
Safecare 250 mg Injection (Medico Health Care)$ 0.56

References

  1. DailyMed. "CEFTRIAXONE SODIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailymed/se... (accessed September 18, 2017).
  2. Wikipedia. "ceftriaxone: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Ceftriaxon... (accessed September 18, 2017).
  3. PubChem. "ceftriaxone". https://pubchem.ncbi.nlm.nih.gov/compoun... (accessed September 18, 2017).
  4. FDA Orange Book. "CEFTRIAXONE SODIUM; LIDOCAINE: The publication, Approved Drug Products with Therapeutic Equivalence Evaluations (the List, commonly known as the Orange Book), identifies drug products approved on the basis of safety and effectiveness by the Food and Drug Administration (FDA) under the Federal Food, Drug, and Cosmetic Act (the Act).". https://www.fda.gov/Drugs/InformationOnD... (accessed September 18, 2017).

Reviews

The results of a survey conducted on ndrugs.com for Rotacef are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rotacef. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Rotacef before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Rotacef. To get the time effectiveness of using Rotacef drug by other patients, please click here.
Users%
1 day1
100.0%


Consumer reported age

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