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Actions of Roxithromycin 300MG TABLET in details
Roxithromycin 300MG TABLET prevents bacteria from growing, by interfering with their protein synthesis. Roxithromycin 300MG TABLET binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Roxithromycin 300MG TABLET has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.
How should I take Roxithromycin 300MG TABLET?
This section provides information on the proper use of a number of products that contain erythromycin. It may not be specific to Roxithromycin 300MG TABLET. Please read with care.
- First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A 1-cm (approximately 1/3-inch) strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to come into contact with the infection.
- To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using erythromycin eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.
To help clear up your infection completely, keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For ophthalmic ointment dosage form:
- For treatment of eye infections:
- Adults and children—Use in the eyes up to six times a day as directed by your doctor.
- For prevention of neonatal conjunctivitis and ophthalmia neonatorum:
- Newborn babies—Use in the eyes once at birth.
- For treatment of eye infections:
If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Roxithromycin 300MG TABLET administration
Should be taken on an empty stomach. Take at least 15 min before meals.
Roxithromycin 300MG TABLET pharmacology
Roxithromycin 300MG TABLET is a semi-synthetic macrolide antibiotic. It is very similar in composition, chemical structure and mechanism of action to erythromycin, azithromycin, or clarithromycin. Roxithromycin 300MG TABLET has the following antibacterial spectrum in vitro: Streptococcus agalactiae, Streptococcus pneumoniae (Pneumococcus), Neisseria meningitides (Meningococcus), Listeria monocytogenes, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum, Legionella pneumophila, Helicobacter (Campylobacter), Gardnerella vaginalis, Bordetella pertussis, Moraxella catarrhalis (Branhamella Catarrhalis), and Haemophilus ducreyi. Roxithromycin 300MG TABLET is highly concentrated in polymorphonuclear leukocytes and macrophages, achieving intracellular concentrations greater than those outside the cell. Roxithromycin 300MG TABLET enhances the adhesive and chemotactic functions of these cells which in the presence of infection produce phagocytosis and bacterial lysis. Roxithromycin 300MG TABLET also possesses intracellular bactericidal activity.
- NCIt. "Roxithromycin: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology