Rozgra Uses

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What is Rozgra?

Rozgra is used to treat men who have erectile dysfunction (also called sexual impotence). Rozgra belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works.

Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, Rozgra helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, Rozgra will not work to cause an erection.

Rozgra is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. Rozgra works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart.

Rozgra is available only with your doctor's prescription.

Rozgra indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Rozgra is indicated for the treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worsening. The delay in clinical worsening was demonstrated when Rozgra was added to background epoprostenol therapy.

Studies establishing effectiveness were short-term (12 to 16 weeks), and included predominately patients with New York Heart Association (NYHA) Functional Class II–III symptoms and idiopathic etiology (71%) or associated with connective tissue disease (CTD) (25%).

Limitation of Use: Adding Rozgra to bosentan therapy does not result in any beneficial effect on exercise capacity.

How should I use Rozgra?

Use Rozgra suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet with detailed instructions for use is available with Rozgra suspension. Talk to your pharmacist if you have questions about this information.
  • Take Rozgra suspension by mouth with or without food. Take your doses 4 to 6 hours apart unless your doctor tells you otherwise.
  • Shake well for at least 10 seconds before each use.
  • Use the oral dosing syringe that comes with Rozgra suspension to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Do not mix Rozgra suspension with other medicine or flavoring.
  • Wash and dry the dosing syringe after each use.
  • Take Rozgra suspension on a regular schedule to get the most benefit from it. Take it at the same times each day.
  • Continue to take Rozgra suspension even if you feel well. Do not miss any doses.
  • Do not suddenly stop taking Rozgra suspension or change your dose without talking to your doctor.
  • If you miss a dose of Rozgra suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rozgra suspension.

Uses of Rozgra in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.
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Rozgra is used to treat men with inability to achieve and maintain penile erection sufficient for satisfactory sexual performance, and for the treatment of increased pressure in the blood vessels of lung (pulmonary arterial hypertension).

Rozgra description

Each film-coated tablet contains Sildenafil equivalent to 50 mg Rozgra.

Each film-coated tablet contains Sildenafil equivalent to 100 mg Rozgra.

Each orodispersible tablet contains Sildenafil equivalent to 50 mg Rozgra.

Excipients/Inactive Ingredients: Film-Coated Tablets: In addition to the active ingredient, Rozgra, each tablet contains the following inactive ingredients: Microcrystalline cellulose, calcium hydrogen phosphate (anhydrous), croscarmellose sodium, magnesium stearate, hydroxypropyl methylcellulose (hypromellose), titanium dioxide (E171), lactose, triacetin, and FD & C Blue #2 aluminum lake [indigo carmine aluminum lake (E132)].

Orodispersible Tablets: In addition to the active ingredient, Rozgra, each orodispersible tablet contains the following inactive ingredients: Microcrystalline cellulose, silica hydrophobic colloidal, croscarmellose sodium, magnesium stearate, indigo carmine aluminium lake (E132), sucralose, mannitol, crospovidone, polyvinyl acetate, povidone, flavouring (contains: Maltodextrin and dextrin), natural flavouring (contains: Maltodextrin, E422 glycerol and E1520 propylene glycol), lemon flavouring (contains: Maltodextrin and E307 alpha tocopherol).

Rozgra dosage

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Rozgra Tablets And

Oral Suspension

The recommended dose of Rozgra is 5 mg or 20 mg three times a day. Administer Rozgra doses 4-6 hours apart.

In the clinical trial no greater efficacy was achieved with the use of higher doses. Treatment with doses higher than 20 mg three times a day is not recommended.

Rozgra Injection

Rozgra injection is for the continued treatment of patients with PAH who are currently prescribed oral Rozgra and who are temporarily unable to take oral medication.

The recommended dose is 2.5 mg or 10 mg administered as an intravenous bolus injection three times a day. The dose of Rozgra injection does not need to be adjusted for body weight.

A 10 mg dose of Rozgra injection is predicted to provide pharmacological effect of Rozgra and its N-desmethyl metabolite equivalent to that of a 20 mg oral dose.

Reconstitution Of The Powder For

Oral Suspension

  1. Tap the bottle to release the powder.
  2. Remove the cap.
  3. Accurately measure out 60 mL of water and pour the water into the bottle. (Figure 1)
  4. Replace the cap and shake the bottle vigorously for a minimum of 30 seconds. (Figure 2)
  5. Remove the cap.
  6. Accurately measure out another 30 mL of water and add this to the bottle. You should always add a total of 90 mL of water irrespective of the dose prescribed. (Figure 3)
  7. Replace the cap and shake the bottle vigorously for a minimum of 30 seconds. (Figure 4)
  8. Remove the cap.
  9. Press the bottle adaptor into the neck of the bottle (as shown on Figure 5, below). The adaptor is provided so that you can fill the oral syringe with medicine from the bottle. Replace the cap on the bottle.
  10. Write the expiration date of the constituted oral suspension on the bottle label (the expiration date of the constituted oral suspension is 60 days from the date of constitution).
Incompatibilities

Do not mix with any other medication or additional flavoring agent.

How supplied

Dosage Forms And Strengths

Rozgra Tablets

White, film-coated, round tablets engraved with “RVT20” containing Rozgra equivalent to 20 mg of Rozgra.

Rozgra Injection

Single use vial containing 10 mg/12.5 mL of Rozgra.

Rozgra for

Oral Suspension

White to off-white powders containing 1.57 g of Rozgra (equivalent to 1.12 g of Rozgra) in a bottle intended for constitution. Following constitution with 90 mL of water, the volume of the oral suspension is 112 mL and the oral suspension contains 10 mg/mL Rozgra. A 2 mL oral syringe (with 0.5 mL and 2 mL dose markings) and a press-in bottle adaptor are also provided.

Storage And Handling

Rozgra tablets are supplied as white, film-coated, round tablets containing Rozgra equivalent to the nominally indicated amount of Rozgra as follows:

Rozgra Tablets
Package Configuration Strength NDC Engraving on Tablet
Bottle of 90 Tablets 20 mg 0069-4190-68 RVT20

Recommended Storage for Rozgra Tablets: Store at controlled room temperature 20°C - 25°C (68°F - 77°F); excursions permitted to 15°C - 30°C (59°F -86°F).

Rozgra injection is supplied as a clear, colorless, sterile, ready to use solution containing 10 mg Rozgra/12.5 mL presented in a single-use glass vial.

Rozgra Injection
Package Configuration Strength NDC
Vial individually packaged in a carton 10 mg /12.5 mL 0069-0338-01

Recommended Storage for Rozgra Injection: Store at controlled room temperature 20°C - 25°C (68°F -77°F); excursions permitted to 15°C - 30°C (59°F - 86°F).

Rozgra powder for oral suspension is supplied in amber glass bottles. Each bottle contains white to off-white powders containing 1.57 g of Rozgra (equivalent to 1.12 g Rozgra). Following constitution, the volume of the oral suspension is 112 mL (10 mg Rozgra/mL). A 2 mL oral dosing syringe (with 0.5 mL and 2 mL dose markings) and a press-in bottle adaptor are also provided.

Rozgra Powder for

Oral Suspension

Package Configuration Strength NDC
Powder for oral suspension - bottle 10 mg/mL (when reconstituted) 0069-0336-21

Recommended storage for Rozgra for oral suspension: Store below 30°C (86°F) in the original package in order to protect from moisture.

Constituted

Oral Suspension

Store below 30°C (86°F) or in refrigerator at 2°C to 8°C (36° F - 46°F). Do not freeze. The shelf-life of the constituted oral suspension is 60 days. Any remaining oral suspension should be discarded 60 days after constitution.

Distributed by: Pfizer Labs, Division of Pfizer Inc., NY, NY 10017. Revised: Apr 2015

Rozgra interactions

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What other drugs will affect Rozgra?

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Effects of Other Drugs on Rozgra Rozgra Citrate

In Vitro Studies: Rozgra Rozgra metabolism is principally mediated by the cytochrome P450 (CYP) isoforms 3A4 (major route) and 2C9 (minor route). Therefore, inhibitors of these isoenzymes may reduce Rozgra clearance.

In Vivo Studies: Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma Rozgra concentrations when coadministered with Rozgra (50 mg) to healthy volunteers.

When a single 100 mg dose of Rozgra was administered with erythromycin, a specific CYP3A4 inhibitor, at steady state (500 mg bid for 5 days), there was a 182% increase in Rozgra systemic exposure (AUC). In addition, coadministration of the HIV protease inhibitor saquinavir, also a CYP3A4 inhibitor, at steady state (1200 mg tid) with Rozgra (100 mg single dose) resulted in a 140% increase in Rozgra Cmax and a 210% increase in Rozgra AUC. Rozgra Rozgra citrate had no effect on saquinavir pharmacokinetics. Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole would be expected to have still greater effects, and population data from patients in clinical trials did indicate a reduction in Rozgra clearance when it was coadministered with CYP3A4 inhibitors (such as ketoconazole, erythromycin, or cimetidine).

Coadministration with the HIV protease inhibitor ritonavir, which is a highly potent P450 inhibitor, at steady state (400 mg bid) with Rozgra (100 mg single dose) resulted in a 300% (4-fold) increase in Rozgra Cmax and a 1000% (11-fold) increase in Rozgra plasma AUC. At 24 hours the plasma levels of Rozgra were still approximately 200 ng/mL, compared to approximately 5 ng/mL when Rozgra was dosed alone. This is consistent with ritonavirs marked effects on a broad range of P450 substrates. Rozgra Rozgra citrate had no effect on ritonavir pharmacokinetics.

It can be expected that concomitant administration of CYP3A4 inducers, such as rifampin, will decrease plasma levels of Rozgra.

Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of Rozgra.

Pharmacokinetic data from patients in clinical trials showed no effect on Rozgra pharmacokinetics of CYP2C9 inhibitors (such as tolbutamide, warfarin), CYP2D6 inhibitors (such as selective serotonin reuptake inhibitors, tricyclic antidepressants), thiazide and related diuretics, ACE inhibitors, and calcium channel blockers. The AUC of the active metabolite, N-desmethyl Rozgra, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. These effects on the metabolite are not expected to be of clinical consequence.

Effects of Rozgra Rozgra Citrate on Other Drugs

In Vitro Studies: Rozgra Rozgra is a weak inhibitor of the cytochrome P450 isoforms 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 (IC50 >150 mM). Given Rozgra peak plasma concentrations of approximately 1 mcM after recommended doses, it is unlikely that Rozgra will alter the clearance of substrates of these isoenzymes.

In Vivo Studies: When Rozgra 100 mg oral was coadministered with amlodipine, 5 mg or 10 mg oral, to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic.

No significant interactions were shown with tolbutamide (250 mg) or warfarin (40 mg), both of which are metabolized by CYP2C9.

Rozgra Rozgra citrate (50 mg) did not potentiate the increase in bleeding time caused by aspirin (150 mg).

Rozgra Rozgra citrate (50 mg) did not potentiate the hypotensive effect of alcohol in healthy volunteers with mean maximum blood alcohol levels of 0.08%.

Rozgra Rozgra (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.

Rozgra side effects

See also:
What are the possible side effects of Rozgra?

The following serious adverse events are discussed elsewhere in the labeling:

  • Mortality with pediatric use
  • Hypotension
  • Vision loss
  • Hearing loss
  • Priapism
  • Vaso-occlusive crisis

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Safety data of Rozgra in adults were obtained from the 12-week, placebo-controlled clinical study (Study 1) and an open-label extension study in 277 Rozgra-treated patients with PAH, WHO Group I.

The overall frequency of discontinuation in Rozgra-treated patients on 20 mg three times a day was 3% and was the same for the placebo group.

In Study 1, the adverse reactions that were reported by at least 3% of Rozgra-treated patients (20 mg three times a day) and were more frequent in Rozgra-treated patients than in placebo-treated patients are shown in Table 1. Adverse reactions were generally transient and mild to moderate in nature.

Table 1: Most Common Adverse Reactions in Patients with PAH in Study 1 (More Frequent in Rozgra-Treated Patients than Placebo-Treated Patients and Incidence ≥ 3% in Rozgra-Treated Patients)

Placebo, %

(n = 70)

Rozgra 20 mg three times a day, %

(n = 69)

Placebo-Subtracted, %
Epistaxis 1 9 8
Headache 39 46 7
Dyspepsia 7 13 6
Flushing 4 10 6
Insomnia 1 7 6
Erythema 1 6 5
Dyspnea exacerbated 3 7 4
Rhinitis 0 4 4
Diarrhea 6 9 3
Myalgia 4 7 3
Pyrexia 3 6 3
Gastritis 0 3 3
Sinusitis 0 3 3
Paresthesia 0 3 3

At doses higher than the recommended 20 mg three times a day, there was a greater incidence of some adverse reactions including flushing, diarrhea, myalgia and visual disturbances. Visual disturbances were identified as mild and transient, and were predominately color-tinge to vision, but also increased sensitivity to light or blurred vision.

The incidence of retinal hemorrhage with Rozgra 20 mg three times a day was 1.4% versus 0% placebo and for all Rozgra doses studied was 1.9% versus 0% placebo. The incidence of eye hemorrhage at both 20 mg three times a day and at all doses studied was 1.4% for Rozgra versus 1.4% for placebo. The patients experiencing these reactions had risk factors for hemorrhage including concurrent anticoagulant therapy.

In a placebo-controlled fixed dose titration study (Study 2) of Rozgra (starting with recommended dose of 20 mg and increased to 40 mg and then 80 mg all three times a day) as an adjunct to intravenous epoprostenol in patients with PAH, the adverse reactions that were more frequent in the Rozgra + epoprostenol group than in the epoprostenol group (greater than 6% difference) are shown in Table 2.

Table 2: Adverse Reactions (%) in patients with PAH in Study 2 (incidence in Rozgra + Epoprostenol group at least 6% greater than Epoprostenol group)

Rozgra + Epoprostenol

(n = 134)

Epoprostenol

(n = 131)

(Rozgra + Epoprostenol) minus Epoprostenol
Headache 57 34 23
Edema^ 25 13 14
Dyspepsia 16 2 14
Pain in extremity 17 6 11
Diarrhea 25 18 7
Nausea 25 18 7
Nasal congestion 9 2 7
^includes peripheral edema

Rozgra Injection

Rozgra injection was studied in a 66-patient, placebo-controlled study in patients with PAH at doses targeting plasma concentrations between 10 and 500 ng/mL (up to 8 times the exposure of the recommended dose). Adverse events with Rozgra injection were similar to those seen with oral tablets.

Postmarketing Experience

The following adverse reactions have been identified during post approval use of Rozgra (marketed for both PAH and erectile dysfunction). Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Cardiovascular Events

In postmarketing experience with Rozgra at doses indicated for erectile dysfunction, serious cardiovascular, cerebrovascular, and vascular events, including myocardial infarction, sudden cardiac death, ventricular arrhythmia, cerebrovascular hemorrhage, transient ischemic attack, hypertension, pulmonary hemorrhage, and subarachnoid and intracerebral hemorrhages have been reported in temporal association with the use of the drug. Most, but not all, of these patients had preexisting cardiovascular risk factors. Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of Rozgra without sexual activity. Others were reported to have occurred hours to days after use concurrent with sexual activity. It is not possible to determine whether these events are related directly to Rozgra, to sexual activity, to the patient's underlying cardiovascular disease, or to a combination of these or other factors.

Nervous system

Seizure, seizure recurrence

Rozgra contraindications

See also:
What is the most important information I should know about Rozgra?

Do not take Rozgra if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Rozgra with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of Rozgra.

Do not take Rozgra more than once a day. Allow 24 hours to pass between doses. Do not take Rozgra while also taking Rozgra, unless your doctor tells you to.

Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Rozgra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Rozgra, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Rozgra is the actual cause of vision loss.

Stop using Rozgra and get emergency medical help if you have sudden vision loss.



Active ingredient matches for Rozgra:

Sildenafil in Indonesia.

Sildenafil citrate in Indonesia.


List of Rozgra substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
S FILM 50MG TABLET 1 strip / 30 tablets each (Delvin Formulations Pvt Ltd)$ 14.05
S FILM STRIP 1 packet / 5 strips each (Delvin Formulations Pvt Ltd)$ 2.54
S-FILM orally disintegrating tab 50 mg x 1's (Delvin)$ 0.56
S-FILM 50mg Disintegrating Strip (Delvin)$ 0.51
Sabu 50mg TAB / 6 (Trugen Pharmaceuticals Pvt. Ltd)$ 1.43
Sabu 100mg TAB / 6 (Trugen Pharmaceuticals Pvt. Ltd)$ 2.86
Sabu 50 mg Tablet (Trugen Pharmaceuticals Pvt. Ltd)$ 0.24
Sabu 100 mg Tablet (Trugen Pharmaceuticals Pvt. Ltd)$ 0.48
50 mg x 4's (Cyno Pharmaceuticals Ltd.)$ 1.50
100 mg x 4's (Cyno Pharmaceuticals Ltd.)$ 2.19
Sanagra 50 mg Tablet (Cyno Pharmaceuticals Ltd.)$ 0.38
Sanagra 50mg TAB / 4 (Cyno Pharmaceuticals Ltd.)$ 1.50
Sanagra 100mg TAB / 4 (Cyno Pharmaceuticals Ltd.)$ 2.19
SANAGRA tab 50 mg x 4's (Cyno Pharmaceuticals Ltd.)$ 1.50
SANAGRA tab 100 mg x 4's (Cyno Pharmaceuticals Ltd.)$ 2.19
Sanagra 50mg TAB / 4 (Cyno Pharmaceuticals Ltd.)$ 1.50
Sanagra 100mg TAB / 4 (Cyno Pharmaceuticals Ltd.)$ 2.19
Sandoz Sildenafil tablet 50 mg (Sandoz Canada Incorporated (Canada))
Sandoz Sildenafil tablet 100 mg (Sandoz Canada Incorporated (Canada))
Sandoz Sildenafil tablet 25 mg (Sandoz Canada Incorporated (Canada))
Satisfaction 50mg TAB / 1x9x10 (Moraceae Pharmaceuticals (P) Ltd.)$ 32.06
Satisfaction 100mg TAB / 1x4x10 (Moraceae Pharmaceuticals (P) Ltd.)$ 24.92
50 mg x 90's (Moraceae Pharmaceuticals (P) Ltd.)$ 32.06
100 mg x 40's (Moraceae Pharmaceuticals (P) Ltd.)$ 24.92
Satisfaction 50 mg Tablet (Moraceae Pharmaceuticals (P) Ltd.)$ 0.36
Satisfaction 100 mg Tablet (Moraceae Pharmaceuticals (P) Ltd.)$ 0.62
SATISFACTION 100 MG TABLET 1 strip / 10 tablets each (Moraceae Pharmaceuticals (P) Ltd.)$ 2.38
SATISFACTION GEL 1 tube / 10 GM gel each (Moraceae Pharmaceuticals (P) Ltd.)$ 0.75
SATISFACTION tab 50 mg x 10's (Moraceae Pharmaceuticals (P) Ltd.)$ 3.56
SATISFACTION tab 100 mg x 4's (Moraceae Pharmaceuticals (P) Ltd.)$ 2.49
Satisfaction 100mg Tablet (Moraceae Pharmaceuticals (P) Ltd.)$ 0.24
SATISFIL 50 MG TABLET 1 strip / 4 tablets each (Tripada Healthcare Pvt Ltd)$ 1.09
Satisfil 50mg Tablet (Tripada Healthcare Pvt Ltd)$ 0.27
50 mg x 4's (Edward)$ 1.11
100 mg x 4's (Edward)$ 1.75
Scanip 50mg TAB / 4 (Edward)$ 1.11
Scanip 100mg TAB / 4 (Edward)$ 1.75
SCANIP tab 50 mg x 4's (Edward)$ 1.11

References

  1. PubChem. "sildenafil". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "sildenafil". http://www.drugbank.ca/drugs/DB00203 (accessed September 17, 2018).
  3. MeSH. "Urological Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Rozgra are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rozgra. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Rozgra before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Rozgra. To get the time effectiveness of using Rozgra drug by other patients, please click here.
Users%
1 month1
100.0%


2 consumers reported age

Users%
> 601
50.0%
46-601
50.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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