Salbutamol CF Uses

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What is Salbutamol CF?

Albuterol is used to treat or prevent bronchospasm in patients with asthma, bronchitis, emphysema, and other lung diseases. This medicine is also used to prevent wheezing caused by exercise (exercise-induced bronchospasm).

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that are breathed in through the mouth to open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, albuterol is used in certain patients with the following medical condition:

Salbutamol CF indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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As a bronchodilator in the treatment of bronchospasm associated with bronchial asthma, emphysema and chronic bronchitis and other conditions associated with reversible airways obstruction. Salbutamol CF also decreases uterine contractility and arrests premature labor.

Uses of Salbutamol CF in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Salbutamol CF is used to prevent reversible airways obstruction occurring during asthma, infections of airway passages (bronchitis), lung disorder in which the flow of air to the lungs is blocked (emphysema), and other lung diseases.

Salbutamol CF description

Each 200 mcg/dose powder for inhalation solution contains Salbutamol sulphate equivalent to Salbutamol CF 200 mcg per metered dose. The dose, which the patient gets through the mouthpiece of the device is Salbutamol CF 180 mcg.

It contains lactose monohydrate (milk protein) as excipient.

The Salbutamol CF multiple dose powder inhaler contains 200 doses of finely powdered Salbutamol CF sulphate mixed in a small quantity of lactose. The amount of drug received by the patient (180 mcg/dose) corresponds to that from Salbutamol CF inhalation aerosol. The dose to be inhaled is released from the container by pressing the device between the thumb and forefinger. This is followed by inhalation through the device. As a result, Salbutamol CF particles are transferred to their target, the lungs. Use of the Salbutamol CF does not require coordination of actuation of the dose and inhalation.

Salbutamol CF dosage

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Tablet: Adults: Usual Dose: 4 mg or 10 mL (2 tsp) of syrup. If adequate bronchodilation is not obtained, each single dose may be gradually increased to as much as 8 mg or 20 mL (4 tsp) of syrup.

To be taken every 6 or 8 hrs.

In some patients known to be unusually sensitive to β-adrenergic stimulant drugs who obtain adequate relief with 5 mL of syrup, it is advisable to initiate treatment with 5 mL (1 tsp) of syrup 3 or 4 times a day.

Children >12 years: 2-4 mg or 5-10 mL (1-2 tsp) of syrup; 6-12 years: 2 mg or 5 mL (1 tsp) of syrup; 2-6 years: 1-2 mg or 2.5-5 mL (½-1 tsp) of syrup.

Nebulizing Solution: Adults and Adolescents: Usual Dose: The usual initial dose of Salbutamol CF by wet inhalation is 2.5-5 mg. Treatment may be repeated up to 4 times daily. In adults, higher dosing up to 40 mg/day can be given under strict medical supervision in hospital for the treatment of severe airway obstruction.

Children up to 12 years: Dosage has not been established. Note: As there may be adverse effects associated with excessive dosing, the dosage or frequency of administration should only be increased on medical advice.

Administration: Salbutamol CF 1 mg/mL nebulizing solution for inhalation is given undiluted using a nebulizer, under the direction of a physician. However, if prolonged administration is desired (>10 min), the solution can be diluted with 0.9% sodium chloride solution.

Direction for Dilution/Prolonged Inhalation: Pipette 2.5-5 mL (equivalent to 2.5-5 mg Salbutamol CF, as sulfate) of Salbutamol CF nebulizing solution from the bottle by using a calibrated medicine dropper provided in the pack. Drop the solution into an electric nebulizer and dilute it with 2-4 mL normal saline solution and start inhalation. Any unused solution in the chamber of the nebulizer must be discarded. Repeat the same procedure every 8 hrs in a 24-hr period.

Salbutamol CF interactions

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If additional adrenergic drugs are administered to patients using Salbutamol CF Easyhaler they should be used with caution to avoid deleterious cardiovascular effects. Patients treated with monoamine oxidase inhibitors or tricyclic antidepressants should be followed clinically in the beginning of Salbutamol CF treatment, because the action of Salbutamol CF on the vascular system may be potentiated. Beta-blockers eg, propranolol, inhibit the effect of Salbutamol CF like that of any other β2-agonists.

The simultaneous administration of xanthines, corticosteroids or potassium excreting diuretics may increase hypokalemia.

Incompatibilities: Not applicable.

Salbutamol CF side effects

See also:
What are the possible side effects of Salbutamol CF?

Salbutamol CF sulfate is generally well tolerated and serious toxic effects are few. The adverse reactions to Salbutamol CF sulfate are similar in nature to reactions to other sympathomimetic agents, although the incidence of certain cardiovascular effects is lower with Salbutamol CF sulfate. The most frequent adverse reactions to Salbutamol CF sulfate are nervousness and tremor. Other reported reactions are headache, tachycardia and palpitations, muscle cramps, insomnia, nausea, weakness and dizziness. Rare cases of urticaria, angioedema, rash and oropharyngeal edema have been reported after the use of Salbutamol CF sulfate. The reactions are generally transient in nature and it is usually not necessary to discontinue treatment with Salbutamol CF sulfate. Inform the physician of the unwanted effects after administering.

Salbutamol CF contraindications

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Hyperthyroidism and cardiac disease. Salbutamol CF may interact with monoamine oxidase inhibitors and should not be given to patients receiving such treatment or within 14 days after stopping treatment.

Use in pregnancy & lactation: Safety in pregnancy and lactating women has not been established.

Salbutamol CF is not indicated for the prevention of premature labor associated with toxemia of pregnancy or ante partum hemorrhage, nor should it be used for threatened abortion during the 1st and 2nd trimesters of pregnancy.

Active ingredient matches for Salbutamol CF:

Salbutamol in Netherlands.


List of Salbutamol CF substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Salbutan 4 mg (Gsk)
Salbutol 4 mg (Brawn Laboratories Ltd.)
Salbutol 100 ml Syrup (Brawn Laboratories Ltd.)$ 0.01
SALBUTOL SYRUP 1 bottle / 100 ML syrup each (Brawn Laboratories Ltd.)$ 0.27
Salbutol Syrup (Brawn Laboratories Ltd.)$ 0.27
Salbutol A 100 ml Syrup (Brawn Laboratories Ltd.)$ 0.02
SALBUTOL A 1MG/15MG SYRUP 1 bottle / 100 ML syrup each (Brawn Laboratories Ltd.)$ 0.35
Salbutol A 15 mg/1 mg Syrup (Brawn Laboratories Ltd.)$ 0.35
Aerosol, Metered-Dose; Inhalation; Albuterol Sulfate 100 mcg / dose (Cassara)
Salbutral 1 tube khГ­ dung 250 lieГ u (Cassara)
Aerosol, Metered-Dose; Inhalation; Albuterol Sulfate 100 mcg / dose
Salbuven 4 mg x 100's (Pharos)$ 21.14
Salbuven 2 mg/5 mL x 100 mL x 1's (Pharos)$ 2.13
Syrup; Oral; Albuterol Sulfate 2 mg / 5 ml (Pharos)
Tablets; Oral; Albuterol Sulfate 4 mg (Pharos)
Saldol 2 mg x 1, 000's
Saldolin 2 mg/1 mL x 2.5 mL x 100's
Powder; Inhalation; Albuterol Hemisuccinate 0.25 mg / dose (Pulmomed)
Solution; Inhalation; Albuterol Hemisuccinate 0.1% (Pulmomed)
Tablet; Oral; Albuterol Hemisuccinate 4 mg (Pulmomed)
Tablets; Oral; Albuterol Hemisuccinate 4 mg (Pulmomed)
SALMAPLON Capsule/ Tablet / 4mg / 10 units (Khandelwal Laboratories Pvt Ltd.)$ 0.02
SALMAPLON Capsule/ Tablet / 2mg / 10 units (Khandelwal Laboratories Pvt Ltd.)$ 0.01
2 mg x 100's (Khandelwal Laboratories Pvt Ltd.)$ 0.12
4 mg x 100's (Khandelwal Laboratories Pvt Ltd.)$ 0.18
Tablets; Oral; Albuterol 2 mg (Khandelwal Laboratories Pvt Ltd.)
Tablets; Oral; Albuterol 4 mg (Khandelwal Laboratories Pvt Ltd.)
Salmaplon 2 mg Tablet (Khandelwal Laboratories Pvt Ltd.)$ 0.00
Salmaplon 4 mg Tablet (Khandelwal Laboratories Pvt Ltd.)$ 0.00

References

  1. DailyMed. "ALBUTEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Salbutamol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Salbutamol". http://www.drugbank.ca/drugs/DB01001 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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