Selenase Uses

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What is Selenase?

Selenase is mineral that is found in soil and occurs naturally in certain foods (such as whole grains, Brazil nuts, sunflower seeds, and seafood). Selenase is not produced in the body, but it is needed for proper thyroid and immune system function.

Selenase is used to treat or prevent Selenase deficiency.

Selenase has been used in alternative medicine as an aid to treat Hashimoto's thyroiditis (an autoimmune disorder of the thyroid), and to treat high cholesterol.

Not all uses for Selenase have been approved by the FDA. Selenase should not be used in place of medication prescribed for you by your doctor.

Selenase may also be used for purposes not listed in this product guide.

Selenase indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Selenase deficiency

Adult: 100-500 mcg of Selenase daily.

Intramuscular

Selenase deficiency

Adult: 100-500 mcg of Selenase daily.

Intravenous

Selenase deficiency

Adult: 100-500 mcg of Selenase daily.

Uses of Selenase in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Selenase is used as a dietary supplement mainly in the treatment of Selenase deficiency affecting young women and children with Keshan disease. It is also used for treatment of osteoarthiritis associated with poor Selenase levels in body called Kashin-Beck Disease. Selenase supplements are also used in patients with HIV/ AIDS to maintain the adequate Selenase levels.

Selenase dosage

Selenase Injection provides 40 mcg Selenase/mL. For metabolically stable adults receiving TPN, the suggested additive dosage level is 20 to 40 mcg Selenase/day. For pediatric patients, the suggested additive dosage level is 3 mcg/kg/day.

In adults, Selenase deficiency states resulting from long-term TPN support, Selenase as selenomethionine or selenious acid, administered intravenously at 100 mcg/day for a period of 24 and 31 days, respectively, has been reported to reverse deficiency symptoms without toxicity.

Aseptic addition of Selenase Injection to the TPN solution under laminar flow hood is recommended. Selenase is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. Frequent monitoring of plasma Selenase levels is suggested as a guideline for subsequent administration. The normal whole blood range for Selenase is approximately 10 to 37 mcg/100 mL.

Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.

Selenase interactions

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What other drugs will affect Selenase?

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Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination

Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification

Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification

Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification

Dolutegravir: Selenase may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Selenase. Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Selenase. Consider therapy modification

Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification

Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification

PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification

Raltegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Raltegravir. Management: Administer raltegravir 2 hours before or 6 hours after administration of the polyvalent cations. Dose separation may not adequately minimize the significance of this interaction. Consider therapy modification

Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification

Selenase side effects

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What are the possible side effects of Selenase?

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No Selenase-related adverse reactions have been reported in clinical studies or postmarketing reports in patients receiving intravenously administered PN solutions containing selenious acid within the recommended dosage range.

The following adverse reactions associated with use of other components of PN solutions were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure:

Selenase contraindications

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What is the most important information I should know about Selenase?

Selenase Injection should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis.

Active ingredient matches for Selenase:

Sodium Selenite in Austria, Czech Republic, Germany, Netherlands, Switzerland, Turkey.


Unit description / dosage (Manufacturer)Price, USD
Injectable; Injection; Selenium / Sodium Selenite 166.5 mcg / ml
Solution; Oral; Selenium / Sodium Selenite 166.5 mcg / ml

List of Selenase substitutes (brand and generic names):

Tablet; Oral; Selenium 50 mcg
Tablet; Oral; Selenium / Yeast 200 mcg
Tablet; Oral; Selenium / Yeast 50 mcg
Tablet; Oral; Selenium / Selenium HVP Chelate 200 mcg
Tablet; Oral; Selenium / Sodium Selenite 200 mcg
Tablet; Oral; Selenium / Yeast 100 mcg
Tablet, Extended Release; Oral; Selenium 50 mcg
Drug Premix; Oral; Selenium / Sodium Selenite 10 g / kg
Drug Premix; Oral; Selenium / Sodium Selenite 200 mg / kg
Tablet; Oral; Selenium 200 mcg
Drops; Oral; Selenium 4 ch
Tablet; Oral; Selenium / Selenium HVP Chelate 100 mcg
Capsule; Oral; Selenium / Sodium Selenite 30 mcg
Capsule; Oral; Selenium / Selenium HVP Chelate 200 mcg
Capsule; Oral; Selenium / Selenium HVP Chelate 100 mcg
Tablet; Oral; Selenium 10 x
Tablet; Oral; Selenium / Selenium Yeast 200 mcg
Injectable; Injection; Selenium / Sodium Selenite 10 mcg / ml
Drug Premix; Oral; Selenium / Sodium Selenite 100 mg / kg
Drops; Oral; Selenium 3 ch
Aerosol with propellants; Oral; Selenium / Sodium Selenite 50 mcg / ml
Solution; Oral; Sodium Selenite 200 mcg / 5 ml

Reviews

The results of a survey conducted on ndrugs.com for Selenase are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Selenase. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Selenase drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Selenase before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 week and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Selenase. To get the time effectiveness of using Selenase drug by other patients, please click here.
Users%
1 week1
100.0%


2 consumers reported age

Users%
30-452
100.0%


Consumer reviews


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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