Skajilol Uses

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Skajilol indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Hypertension

Adult: 200 mg/day in divided doses, increased wkly according to patient response.

Oral

Angina pectoris; Cardiac arrhythmias

Adult: 200-400 mg/day in divided doses.

Skajilol description

One of the adrenergic beta-antagonists used as an antihypertensive, anti-anginal, and anti-arrhythmic agent. Skajilol is no longer marketed by AstraZeneca, but may still be available in generic varieties.

Skajilol dosage

Oral

Hypertension

Adult: 200 mg/day in divided doses, increased wkly according to patient response.

Oral

Angina pectoris; Cardiac arrhythmias

Adult: 200-400 mg/day in divided doses.

Skajilol interactions

Concomitant use w/ other drugs that cause hypotension; NSAIDs; other cardiac depressants; sotalol; digoxin; insulin and oral hypoglycaemics; sympathomimetics; ACE inhibitors; Ca-channel blockers, verapamil. Anaesthetics causing myocardial depression (e.g. ether, cyclopropane, trichloroethylene).

Potentially Fatal: Increased risk of withdrawal HTN w/ clonidine. Withdraw several days before slowly discontinuing clonidine.

Skajilol side effects

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Bradycardia; heart failure, heart block; hypotension; bronchospasm; fatigue; coldness of extremities; pneumonitis; pulmonary and retroperitoneal fibrosis; pleurisy; CNS effects; myopathies; GI disturbances; reversible alopoecia; skin rash; pruritus; lupus-like syndrome; male impotence; sclerosing peritonitis; muscle cramps; paraesthesias; peripheral neuropathy; haematological reactions. Changes in blood concentrations of glucose, triglycerides and cholesterol.

Skajilol contraindications

2nd and 3rd degree AV block; sinus bradycardia; uncontrolled heart failure; asthma or bronchospasm, severe peripheral arterial disease, metabolic acidosis, phaeochromocytoma. Concomitant use w/ clonidine.

Active ingredient matches for Skajilol:

Alprenolol in Japan.


List of Skajilol substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Elp 50 mg x 500's (Shyh Dar)
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Elp 50 mg x 100 x 10's (Shyh Dar)

References

  1. PubChem. "alprenolol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "alprenolol". http://www.drugbank.ca/drugs/DB00866 (accessed September 17, 2018).
  3. Wikipedia. "alprenolol: Link to the compound information in Wikipedia.". https://en.wikipedia.org/wiki/Alpren... (accessed September 17, 2018).
  4. MeSH. "Sympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
  5. European Chemicals Agency - ECHA. "alprenolol: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Skajilol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Skajilol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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