Sodium Selenite Uses

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What is Sodium Selenite?

Sodium Selenite is mineral that is found in soil and occurs naturally in certain foods (such as whole grains, Brazil nuts, sunflower seeds, and seafood). Sodium Selenite is not produced in the body, but it is needed for proper thyroid and immune system function.

Sodium Selenite is used to treat or prevent Sodium Selenite deficiency.

Sodium Selenite has been used in alternative medicine as an aid to treat Hashimoto's thyroiditis (an autoimmune disorder of the thyroid), and to treat high cholesterol.

Not all uses for Sodium Selenite have been approved by the FDA. Sodium Selenite should not be used in place of medication prescribed for you by your doctor.

Sodium Selenite may also be used for purposes not listed in this product guide.

Sodium Selenite indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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Oral

Sodium Selenite deficiency

Adult: 100-500 mcg of Sodium Selenite daily.

Intramuscular

Sodium Selenite deficiency

Adult: 100-500 mcg of Sodium Selenite daily.

Intravenous

Sodium Selenite deficiency

Adult: 100-500 mcg of Sodium Selenite daily.

Uses of Sodium Selenite in details

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Sodium Selenite is used as a dietary supplement mainly in the treatment of Sodium Selenite deficiency affecting young women and children with Keshan disease. It is also used for treatment of osteoarthiritis associated with poor Sodium Selenite levels in body called Kashin-Beck Disease. Sodium Selenite supplements are also used in patients with HIV/ AIDS to maintain the adequate Sodium Selenite levels.

Sodium Selenite dosage

Sodium Selenite Injection provides 40 mcg Sodium Selenite/mL. For metabolically stable adults receiving TPN, the suggested additive dosage level is 20 to 40 mcg Sodium Selenite/day. For pediatric patients, the suggested additive dosage level is 3 mcg/kg/day.

In adults, Sodium Selenite deficiency states resulting from long-term TPN support, Sodium Selenite as selenomethionine or selenious acid, administered intravenously at 100 mcg/day for a period of 24 and 31 days, respectively, has been reported to reverse deficiency symptoms without toxicity.

Aseptic addition of Sodium Selenite Injection to the TPN solution under laminar flow hood is recommended. Sodium Selenite is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. Frequent monitoring of plasma Sodium Selenite levels is suggested as a guideline for subsequent administration. The normal whole blood range for Sodium Selenite is approximately 10 to 37 mcg/100 mL.

Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.

Sodium Selenite interactions

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What other drugs will affect Sodium Selenite?

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Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination

Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification

Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification

Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification

Dolutegravir: Sodium Selenite may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Sodium Selenite. Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Sodium Selenite. Consider therapy modification

Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification

Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification

PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification

Raltegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Raltegravir. Management: Administer raltegravir 2 hours before or 6 hours after administration of the polyvalent cations. Dose separation may not adequately minimize the significance of this interaction. Consider therapy modification

Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification

Sodium Selenite side effects

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What are the possible side effects of Sodium Selenite?

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No Sodium Selenite-related adverse reactions have been reported in clinical studies or postmarketing reports in patients receiving intravenously administered PN solutions containing selenious acid within the recommended dosage range.

The following adverse reactions associated with use of other components of PN solutions were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure:

Sodium Selenite contraindications

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What is the most important information I should know about Sodium Selenite?

Sodium Selenite Injection should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis.

Active ingredient matches for Sodium Selenite:

Sodium Selenite


Unit description / dosage (Manufacturer)Price, USD
Solution; Oral; Sodium Selenite 200 mcg / 5 ml

List of Sodium Selenite substitutes (brand and generic names):

Solution; Oral; Selenium / Sodium Selenite 166.5 mcg / ml (Biosyn)
Tablet; Oral; Selenium 50 mcg
Tablet; Oral; Selenium / Yeast 200 mcg
Tablet; Oral; Selenium / Yeast 50 mcg
Tablet; Oral; Selenium / Selenium HVP Chelate 200 mcg
Tablet; Oral; Selenium / Sodium Selenite 200 mcg
Tablet; Oral; Selenium / Yeast 100 mcg
Tablet, Extended Release; Oral; Selenium 50 mcg
Drug Premix; Oral; Selenium / Sodium Selenite 10 g / kg
Drug Premix; Oral; Selenium / Sodium Selenite 200 mg / kg
Tablet; Oral; Selenium 200 mcg
Drops; Oral; Selenium 4 ch
Tablet; Oral; Selenium / Selenium HVP Chelate 100 mcg
Capsule; Oral; Selenium / Sodium Selenite 30 mcg
Capsule; Oral; Selenium / Selenium HVP Chelate 200 mcg
Capsule; Oral; Selenium / Selenium HVP Chelate 100 mcg
Tablet; Oral; Selenium 10 x
Tablet; Oral; Selenium / Selenium Yeast 200 mcg
Injectable; Injection; Selenium / Sodium Selenite 10 mcg / ml
Drug Premix; Oral; Selenium / Sodium Selenite 100 mg / kg
Drops; Oral; Selenium 3 ch
Aerosol with propellants; Oral; Selenium / Sodium Selenite 50 mcg / ml

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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