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Spiramycine Métronidazole CristerS Uses |
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Metronidazole (Spiramycine Métronidazole CristerS) is indicated for the treatment of symptomatic trichomoniasis in females and males when the presence of thetrichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures).Metronidazole (Spiramycine Métronidazole CristerS) is indicated in the treatment of asymptomatic females when the organism is associated with endocervi-citis, cervicitis, or cervical erosion.
Metronidazole (Spiramycine Métronidazole CristerS) is indicated in the treatment of acute intestinal amebiasis (amebic dysen-tery)and amebic liver abscess.
In amebic liver abscess, Metronidazole (Spiramycine Métronidazole CristerS) therapy does not obviate the need for aspiration or drainage of pus.
Metronidazole (Spiramycine Métronidazole CristerS) is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Indicated surgical procedures should be performed in conjunction with Metronidazole (Spiramycine Métronidazole CristerS) therapy. In a mixed aerobic and anaerobic infection, antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to Flagyl.
INTRA-ABDOMINAL INFECTIONS, including peritonitis, intra-abdominal abscess, and liver abscess, caused by Bacteroides species including the B. fragilis group (B. fragilis, B. distasonis,B. ovatus, B. thetaiotaomicron, B. vulgatus), Clostrid-ium species, Eubacterium species, Peptococcus niger, and Peptostreptococcus species.
SKIN AND SKIN STRUCTURE INFECTIONS caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus niger,Peptostreptococcus species, and Fusobacte-rium species.
GYNECOLOGIC INFECTIONS, including endo-metritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection, caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcusniger, and Pepto-streptococcus species.
BACTERIAL SEPTICEMIA caused by Bacteroides species including the B. fragilis group, and Clos-tridium species.
BONE AND JOINT INFECTIONS, as adjunctive therapy, caused by Bacteroides species including the B. fragilis group.
CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS, including meningitis and brain abscess, caused by Bacteroides species including the B.fragilis group.
LOWER RESPIRATORY TRACT INFECTIONS, including pneumonia, empyema, and lung abscess, caused by Bacteroides species including the B. fragilis group.
ENDOCARDITIS caused by Bacteroides species including the B.fragilis group.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Metronidazole (Spiramycine Métronidazole CristerS) and other antibacterial drugs, Metronidazole (Spiramycine Métronidazole CristerS) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Metronidazole (Spiramycine Métronidazole CristerS) has been reported to potentiate the anticoagulant effect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation of prothrombin time. This possible drug interaction should be considered when Metronidazole (Spiramycine Métronidazole CristerS) (Metronidazole (Spiramycine Métronidazole CristerS)) is prescribed for patients on this type of anticoagulant therapy.
The simultaneous administration of drugs that induce microsomal liver enzymes, such as phe-nytoin or phenobarbital, may accelerate the elimination of Metronidazole (Spiramycine Métronidazole CristerS), resulting in reduced plasma levels; impaired clearance of phenytoin has also been reported.
The simultaneous administration of drugs that decrease microsomal liver enzyme activity, such as cimetidine, may prolong the half-life and decrease plasma clearance of Metronidazole (Spiramycine Métronidazole CristerS). In patients stabilized on relatively high doses of lithium, short-term Metronidazole (Spiramycine Métronidazole CristerS) therapy has been associated with elevation of serum lithium and, in a few cases, signs of lithium toxicity. Serum lithium and serum cre-atinine levels should be obtained several days after beginning Metronidazole (Spiramycine Métronidazole CristerS) to detect any increase that may precede clinical symptoms of lithium intoxication.
Alcoholic beverages should not be consumed during Metronidazole (Spiramycine Métronidazole CristerS) therapy and for at least one day afterward because abdominal cramps, nausea, vomiting, headaches, and flushing may occur.
Psychotic reactions have been reported in alcoholic patients who are using Metronidazole (Spiramycine Métronidazole CristerS) and disulfiram concurrently. Metronidazole (Spiramycine Métronidazole CristerS) should not be given to patients who have taken disulfiram within the last two weeks.
Two serious adverse reactions reported in patients treated with Metronidazole (Spiramycine Métronidazole CristerS) (Metronidazole (Spiramycine Métronidazole CristerS)) have been convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity. Since persistent peripheral neuropathy has been reported in some patients receiving prolonged administration of Metronidazole (Spiramycine Métronidazole CristerS), patients should be specifically warned about these reactions and should be told to stop the drug and report immediately to their physicians if any neu-rologic symptoms occur.
The most common adverse reactions reported have been referable to the gastrointestinal tract, particularly nausea reported by about 12% of patients, sometimes accompanied by headache, anorexia, and occasionally vomiting; diarrhea; epi-gastric distress; and abdominal cramping. Constipation has also been reported.
The following reactions have also been reported during treatment with Metronidazole (Spiramycine Métronidazole CristerS) (Metronidazole (Spiramycine Métronidazole CristerS)):
Mouth: A sharp, unpleasant metallic taste is not unusual. Furry tongue, glossitis, and sto-matitis have occurred; these may be associated with a sudden overgrowth of Candida which may occur during therapy.
Hematopoietic: Reversible neutropenia (leuko-penia); rarely, reversible thrombocytopenia.
Cardiovascular: Flattening of the T-wave may be seen in electrocardiographic tracings.
Central Nervous System: Convulsive seizures, peripheral neuropathy, dizziness, vertigo, incoordination, ataxia, confusion, irritability, depression, weakness, and insomnia.
Hypersensitivity: Urticaria, erythematous rash, flushing, nasal congestion, dryness of the mouth (or vagina or vulva), and fever.
Renal: Dysuria, cystitis, polyuria, incontinence, and a sense of pelvic pressure. Instances of darkened urine have been reported by approximately one patient in 100,000. Although the pigment which is probably responsible for this phenomenon has not been positively identified, it is almost certainly a metabolite of Metronidazole (Spiramycine Métronidazole CristerS) and seems to have no clinical significance.
Other: Proliferation of Candida in the vagina, dyspareunia, decrease of libido, proctitis, and fleeting joint pains sometimes resembling &ldquoserum sickness.” If patients receiving Metronidazole (Spiramycine Métronidazole CristerS) drink alcoholic beverages, they may experience abdominal distress, nausea, vomiting, flushing, or headache. A modification of the taste of alcoholic beverages has also been reported. Rare cases of pan-creatitis, which generally abated on withdrawal of the drug, have been reported.
Crohn’s disease patients are known to have an increased incidence of gastrointestinal and certain extraintestinal cancers. There have been some reports in the medical literature of breast and colon cancer in Crohn’s disease patients who have been treated with Metronidazole (Spiramycine Métronidazole CristerS) at high doses for extended periods of time. A cause and effect relationship has not been established. Crohn’s disease is not an approved indication for Metronidazole (Spiramycine Métronidazole CristerS).
Metronidazole (Spiramycine Métronidazole CristerS) is contraindicated in patients with a prior history of hypersensitivity to Metronidazole (Spiramycine Métronidazole CristerS) or other nitroimidazole derivatives.
Metronidazole/Spiramycin in France.
List of Spiramycine Métronidazole CristerS substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Spiramycine/Métronidazole Almus (France) | |
Spiramycine/Métronidazole Arrow (France) | |
Spiramycine/Métronidazole Biogaran (France) | |
Spiramycine/Métronidazole Cristers (France) | |
Spiramycine/Métronidazole EG (France) | |
Spiramycine/Métronidazole Ranbaxy (France) | |
Spiramycine/Métronidazole Sandoz (France) | |
Spiramycine/Métronidazole Teva (France) | |
Spiramycine/Métronidazole Zentiva (France) | |
Spiramycine/Métronidazole Zydus (France) | |
Spiramycine; Metronidazole | |
Tablet, Film-Coated; Oral; Metronidazole 125 mg; Spiramycin 750, 000 IU | |
Tablet, Film-Coated; Oral; Metronidazole 250 mg; Spiramycin 1, 500, 000 IU | |
Spiranisol (Vietnam) | |
Spiranisol Forte 2 Blister x 10 Tablet | |
Spiranisol 2 Blister x 10 Tablet | |
Spirastad Plus (Vietnam) | |
Spirazol (Tunisia) | |
Spirazole (Egypt) | |
Spirazole forte (Egypt) | |
Spirazolefort | |
Spirogyl (Tunisia) | |
Spiroxan (Italy) | |
Spirumet (Vietnam) | |
Spirumet 1 Blister x 10 Tablet | |
Spizobactin (United Kingdom) | |
Spizobactin vet (Estonia) | |
Spizobactin-L (Iceland) | |
Spizobactin-M (Iceland) | |
Spizobactin-S (Iceland) | |
Spyforce (Vietnam) | |
Spyforce 1 Box | |
Stomorgyl (Australia, Israel, Luxembourg, New Zealand, Poland, Switzerland, United Kingdom) | |
Tablet; Oral; Metronidazole 25 mg; Spiramycin 150, 000 IU / dose | |
Tablet; Oral; Metronidazole 125 mg; Spiramycin 750, 000 IU / dose | |
Tablet; Oral; Metronidazole 250 mg; Spiramycin 1, 500, 000 IU / dose | |
Stomorgyl 10 (Estonia, Israel, Netherlands, Switzerland) | |
Stomorgyl 2 (Estonia, Netherlands) | |
Stomorgyl 20 (Netherlands, Poland) | |
Suanatem (Austria, Germany) | |
Suanatem 23,81 mg + 16,67 mg für Hunde (Austria) | |
Suanatem forte (Austria) | |
Suanatem forte 178.57 mg + 125 mg für Hunde (Austria) | |
Viagogyl (Vietnam) | |
Viagogyl 2 Blister x 10 Tablet | |
Zidocin DHG (Vietnam) | |
Zidocin DHG 2 Blister x 10 Tablet | |
Zolgyl (Vietnam) | |
Zolgyl 2 Blister x 10 Tablet | |
See 106 substitutes for Spiramycine Métronidazole CristerS |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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