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Stellamide Uses |
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Gastro - intestinal disorders, gastric & duodenal ulcer, gastroduodenitis, hypersecretion&hypermotility of gastrointestinal tract, nervous dyspepsia, biliary dyskinesia, irritable & spastic colon, colitis, diarrhoea, ureteric spasm, nocturnal enuresis & dysmenorrhoea.
1 tab bid or as directed.
Phenothiazines may diminish the effect of oral anticoagulants.
Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs.
Phenothiazines may lower the convulsive threshold; dosage adjustment of anticonvulsants may be necessary. Potentiation of anticonvulsant effects does not occur. However, it has been reported that phenothiazines may interfere with the metabolism of phenytoin and thus precipitate phenytoin toxicity.
Drugs which lower the seizure threshold, including phenothiazine derivatives, should not be used with metrizamide. As with other phenothiazine derivatives, trifluoperazine should be discontinued at least 48 hours before myelography, should not be resumed for at least 24 hours post procedure, and should not be used for the control of nausea and vomiting occurring either prior to myelography or post procedure
it may cause akathisia, dystonia, and Parkinsonism. It is also more likely to cause somnolence and anticholinergic side effects such as blurred vision and xerostomia (dry mouth). All phenothiazines can cause the rare and sometimes fatal neuroleptic malignant syndrome. Trifluoperazine can lower the seizure threshold. The antimuscarinic action of trifluoperazine can cause excessive dilation of the pupils (mydriasis), which increases the chances of patients with hyperopia developing glaucoma.
Trifluoperazine is contraindicated in CNS depression, coma, and blood dyscrasias. Trifluoperazine should be used with caution in patients suffering from renal or hepatic impairment.
Isopropamide Iodide/Trifluoperazine Hydrochloride
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Isopropamide Iodide/Trifluoperazine Hydrochloride |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
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