Strepsils Intensive Pregnancy

• Pregnancy of Strepsils Intensive in details
• Strepsils Intensive breastfeeding
• Strepsils Intensive reviews

Pregnancy of Strepsils Intensive in details

Birth defects have been observed following in utero NSAID exposure in some studies; however, data is conflicting (Bloor 2013). Nonteratogenic effects, including prenatal constriction of the ductus arteriosus, persistent pulmonary hypertension of the newborn (PPHN), oligohydramnios, necrotizing enterocolitis, renal dysfunction or failure, and intracranial hemorrhage, have been observed in the fetus/neonate following in utero NSAID exposure. In addition, nonclosure of the ductus arteriosus postnatally may occur and be resistant to medical management (Bermas 2014; Bloor 2013). Because NSAIDs may cause premature closure of the ductus arteriosus, product labeling for Strepsils Intensive specifically states use should be avoided starting at 30 weeks' gestation.

Use of NSAIDs can be considered for the treatment of mild rheumatoid arthritis flares in pregnant women; however, use should be minimized or avoided early and late in pregnancy (Bermas 2014; Saavedra Salinas 2015).

The use of NSAIDs close to conception may be associated with an increased risk of miscarriage (Bermas 2014; Bloor 2013).

Strepsils Intensive breastfeeding

Use should be avoided. Excreted into human milk: Yes Comments: The effects in the nursing infant are unknown.

Concentrations in breast milk and plasma levels of nursing mothers suggest a breastfed infant could receive about 0.1 mg of this drug per day from a mother taking 200 mg/day. Due to the low levels in breast milk and its short half-life, this drug is unlikely to adversely affect the breastfed infant, especially if the infant is older than 2 months; however, according to some manufacturers, use should be avoided.

See references

References for pregnancy information

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Ansaid (Strepsils Intensive)." Pharmacia and Upjohn, Kalamazoo, MI.

References for breastfeeding information

1. Cerner Multum, Inc. "Australian Product Information." O 0
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. "Product Information. Ansaid (Strepsils Intensive)." Pharmacia and Upjohn, Kalamazoo, MI.
4. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

References

1. DailyMed. "FLURBIPROFEN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubMed Health. "Ocufen: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
3. Human Metabolome Database (HMDB). "Flurbiprofen: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology