What happens if I overdose Beclometasone Topical (Suzen-NS Cream)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
An overdose of beclomethasone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.
Overdose of Beclometasone Topical (Suzen-NS Cream) in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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When used at excessive doses, systemic corticosteroid effects eg, hypercorticism and adrenal suppression may occur. If such changes occur, Beclometasone Topical (Suzen-NS Cream) should be discontinued slowly, consistent with acceptable procedures of discontinuing oral steroid therapy. The acute toxicity of beclomethasone dipropionate is low.
What should I avoid while taking Beclometasone Topical (Suzen-NS Cream)?
Avoid getting this medication in your eyes. If this does happen, rinse with water and call your doctor.
Beclomethasone nasal can lower the blood cells that help your body fight infections. Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using beclomethasone nasal.
Beclometasone Topical (Suzen-NS Cream) warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
The replacement of a systemic corticosteroid with beclomethasone dipropionate nasal inhaler or spray can be accompanied by signs of adrenal insufficiency.
Careful attention must be given when patients previously treated for prolonged periods with systemic corticosteroids are transferred to beclomethasone dipropionate nasal inhaler or spray. This is particularly important in those patients who have associated asthma or other clinical conditions where too rapid a decrease in systemic corticosteroids may cause a severe exacerbation of their symptoms.
Studies have shown that combined administration of alternate-day prednisone systemic treatment and orally inhaled beclomethasone dipropionate increases the likelihood of HPA suppression compared to a therapeutic dose of either one alone. Therefore, nasal forms of beclomethasone dipropionate should be used with caution in patients already on alternate day prednisone regimens for any disease.
If recommended doses of intranasal beclomethasone are exceeded or if individuals are particularly sensitive or predisposed by virtue of recent systemic steroid therapy, symptoms of hypercorticism may occur, including very rare cases of menstrual irregularities, acneform lesions, cataracts, and cushingoid features. If such changes occur, this drug should be discontinued slowly consistent with accepted procedures for discontinuing oral steroid therapy.
Persons who are on drugs that suppress the immune system are more susceptible to infections than healthy individuals. Chickenpox and measles, for example, can have a more serious or even fatal course in nonimmune children or adults on corticosteroids. In such children or adults who have not had these diseases, particular care should be taken to avoid exposure of these infectious agents. How the dose, route, and duration of corticosteroid administration affects the risk of developing a disseminated infection is not known. The contribution of the underlying disease and/or prior corticosteroid treatment to the risk of developing a more severe infection is also not known. If exposed to chickenpox, prophylaxis with varicella zoster immune globulin (VZIG) may be indicated. If exposed to measles, prophylaxis with pooled intramuscualr immunoglobulin (IG), may be indicated. If chickenpox develops, treatment with antiviral agents may be considered.
What should I discuss with my healthcare provider before taking Beclometasone Topical (Suzen-NS Cream)?
You should not use this medication if you are allergic to beclomethasone.
Before using beclomethasone, tell your doctor if you have been sick or have had an infection of any kind. You may not be able to use beclomethasone nasal until you are well.
To make sure you can safely use beclomethasone, tell your doctor if you have any of these other conditions:
glaucoma or cataracts;
herpes simplex virus of your eyes;
tuberculosis or any other infection or illness;
sores or ulcers inside your nose; or
if you have recently had injury of or surgery on your nose.
FDA pregnancy category C. It is not known whether beclomethasone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether beclomethasone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Steroid medicines can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using beclomethasone nasal.
Beclometasone Topical (Suzen-NS Cream) should not be given to a child younger than 6 years old. Qnasl should not be given to a child younger than 12 years old.
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
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Patients suffering from tuberculosis should be treated with care. Sinusitis may be treated properly.
Patients should be taught the proper use of Beclometasone Topical (Suzen-NS Cream) to ensure the good clinical efficacy. They should also be aware that Beclometasone Topical (Suzen-NS Cream) has to be used regularly for optimal benefit. Patients should be advised that Beclometasone Topical (Suzen-NS Cream) will not provide immediate symptomatic relief and use of topical nasal decongestant or oral antihistamines may be necessary until the effects of intranasal beclomethasone dipropionate are fully manifested. Infections of the nasal passages and paranasal sinuses should be appropriately treated but do not constitute a specific contraindication to treatment with Beclometasone Topical (Suzen-NS Cream).
Care must be taken while transferring patients from systemic steroid treatment to Beclometasone Topical (Suzen-NS Cream) if there is any reason to suppose that their adrenal function is impaired.
A heavy challenge of summer allergens may, in certain instances, necessitate appropriate additional therapy, particularly to control eye symptoms.
In the continuous long-term treatment with intranasal steroids, the nasal mucosa should be inspected regularly, at least once a year. Intranasal corticosteroid should be used with caution until healing occurs in patients with recent nasal septal ulcers, nasal surgery or nasal trauma, since the drug may inhibit wound healing.
Use in pregnancy & lactation: Administration of corticosteroids to pregnant animals can cause abnormalities of fetal development, including cleft palate and intrauterine growth retardation. There may therefore be a very small risk of such effects in the human fetus. It should be noted, however, that the fetal changes in animals occur after relatively high systemic exposure; direct; intranasal application ensures minimal systemic exposure.
The use of beclomethasone dipropionate during pregnancy requires the possible benefits of Beclometasone Topical (Suzen-NS Cream) be weighed against the possible hazards. It should be noted that the drug has been in widespread use for many years without apparent ill consequence.
The use of beclomethasone dipropionate in mothers breastfeeding their babies requires that the therapeutic benefits of Beclometasone Topical (Suzen-NS Cream) be weighed against the potential hazard to the mother and baby.
Use in children: Use of Beclometasone Topical (Suzen-NS Cream) is not recommended for children <6 years.
Controlled clinical studies have shown that intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. This effect has been observed in the absence of laboratory evidence of hypothalamic-pituitary-adrenal (HPA) axis suppression, suggesting that growth velocity is a more sensitive indicator or systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis function. The long-term effects of this reduction in growth velocity associated with intranasal corticosteroids, including the impact on final adult height, are unknown. The potential for "catch up" growth following discontinuation of treatment with intranasal corticosteroids has not been adequately studied. The growth of pediatric patients receiving intranasal corticosteroids should be monitored routinely (eg, via stadiometry). The potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of safe and effective noncorticosteroid treatment alternatives. To minimize the systemic effects of intranasal corticosteroids, each patient should be titrated to his/her lowest effective dose.
What happens if I miss a dose of Beclometasone Topical (Suzen-NS Cream)?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose Clotrimazole Topical (Suzen-NS Cream)?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Clotrimazole Topical (Suzen-NS Cream) may be harmful if swallowed.
Proper storage of Clotrimazole Topical (Suzen-NS Cream):
Store Clotrimazole Topical (Suzen-NS Cream) at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Clotrimazole Topical (Suzen-NS Cream) out of the reach of children and away from pets.
Overdose of Clotrimazole Topical (Suzen-NS Cream) in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
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This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Notes
Do not share this medication with others.
To help prevent vaginal yeast infections, dry the genital area thoroughly after showering, bathing, or swimming. Avoid wearing tight jeans, nylon underwear, pantyhose, a wet bathing suit, or damp/sweaty exercise clothes for long periods. Wear cotton underwear, and change your underwear daily.
If your sexual partner experiences symptoms, they should contact their doctor right away.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Storage
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
What should I avoid while taking Clotrimazole Topical (Suzen-NS Cream)?
Do not have sexual intercourse. This medicine will not prevent the infection from spreading to your partner. Clotrimazole topical can also cause damage to a condom or a diaphragm. These forms of birth control may be less effective if you use them during treatment.
Avoid getting this medicine in your eyes, nose, or mouth.
Avoid wearing tight-fitting, synthetic clothing that doesn't allow air circulation. Wear clothing made of loose cotton and other natural fibers until the infection is healed.
Clotrimazole Topical (Suzen-NS Cream) warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
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How to use Clotrimazole Topical (Suzen-NS Cream) :Use clotrimazole exactly as directed by your doctor. Always read the manufacturers information leaflet, if possible, before beginning treatment. Clotrimazole Topical (Suzen-NS Cream) preparations are usually applied two to three times a day until the infection has cleared. This medicine is for you. Never give it to others, even if their condition appears to be the same as yours. Getting the most from your treatment : Always wash and dry your hands thoroughly before and after handling clotrimazole. Do not allow clotrimazole to come into contact with the eyes, ears, or mucous membranes (eg. mouth, vagina, inside of nose etc.), unless you are advised to do so by your doctor. Complete the full course of treatment with clotrimazole, otherwise your infection is likely to recur. Before using any over-the-counter medicines, check with your pharmacist which medicines are safe for you to use alongside clotrimazole. You should see an improvement in your condition after a few days. If your condition does not seem to be getting better after seven days, consult your doctor for advice.
What should I discuss with my healthcare provider before taking Clotrimazole Topical (Suzen-NS Cream)?
Some medical conditions may interact with Clotrimazole Topical (Suzen-NS Cream). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have the blood disease porphyria or a history of liver disease or diabetes, or you have been exposed to HIV
if this is the first time you have had vaginal itching and discomfort
if you have vaginal yeast infections often (eg, your symptoms return within 2 months) or your symptoms do not clear up with treatment
if you are taking antibiotics
Some MEDICINES MAY INTERACT with Clotrimazole Topical (Suzen-NS Cream). However, no specific interactions with Clotrimazole Topical (Suzen-NS Cream) are known at this time.
Ask your health care provider if Clotrimazole Topical (Suzen-NS Cream) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Clotrimazole Topical (Suzen-NS Cream) precautions
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
Clotrimazole Topical (Suzen-NS Cream) Cream: Clotrimazole cream may reduce the effectiveness and safety of latex products eg, condoms and diaphragms when applied on the genital area (women: labia and adjacent areas of the vulva; men: prepuce and glans of the penis). The effect is temporary and occurs only during treatment.
Cetostearyl alcohol may cause local skin reactions (eg, contact dermatitis).
As this preparation contains benzyl alcohol, its use should be avoided in children <2 years.
Not to be used in neonates.
Clotrimazole Topical (Suzen-NS Cream)
Topical Powder:
Consult the doctor if no improvement is observed in 4 weeks for athlete's foot.
Use in pregnancy: Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. As a precautionary measure, it is preferable to avoid the use of clotrimazole during the 1st trimester of pregnancy, unless otherwise directed by the physician.
Use in lactation: Breastfeeding should be discontinued during treatment with clotrimazole.
Use in children: Do not use on children <2 years except under the advice and supervision of a physician.
What happens if I miss a dose of Clotrimazole Topical (Suzen-NS Cream)?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
What happens if I overdose Neomycin Topical (Suzen-NS Cream)?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Symptoms may include change in urination frequency or amount of urine.
Proper storage of Neomycin Topical (Suzen-NS Cream):
Store Neomycin Topical (Suzen-NS Cream) at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Neomycin Topical (Suzen-NS Cream) out of the reach of children and away from pets.
Overdose of Neomycin Topical (Suzen-NS Cream) in details
When a dose is taken in higher dose than the recommended doses, it is called Overdose. Overdose always needs a clinical supervision. Any medicine or drug when consumed in Overdose produces untoward side effects on one or various organs in the body. A medicine is excreted in the kidney or metabolized in the liver most of the times. This process goes without any hurdles when taken in normal dose, but when taken in an overdose, the body is not able to metabolize it or send it out properly which causes the effects of anoverdose.
Because of low absorption, it is unlikely that acute overdosage would occur with oral Neomycin Topical (Suzen-NS Cream). However, prolonged administration could result in sufficient systemic drug levels to produce neurotoxicity, ototoxicity and/or nephrotoxicity.
Hemodialysis will remove Neomycin Topical (Suzen-NS Cream) from the blood.
What should I avoid while taking Neomycin Topical (Suzen-NS Cream)?
If you are being treated for hepatic coma, avoid eating foods that are high in protein. Follow your doctor's instructions about any other restrictions on food, beverages, or activity.
Neomycin Topical (Suzen-NS Cream) warnings
Warnings are a mix of Precautions. Contraindications and interactions and serious harmful effects associated with the medicine intake. A diabetic or Hypertensive patient need to be warned about few drug interactions. A known hypersensitivity patient needs to be careful about the reactions or anaphylactic shock. A pregnant woman or a breastfeeding woman should be warned of certain medications. A Hepatitis [liver disease] patient or a cardiac patient should avoid few drugs.
Before administering the drug, patients or members of their families should be informed of possible toxic effects on the eighth nerve. The possibility of acute toxicity increases in premature infants and neonates.
What should I discuss with my healthcare provider before taking Neomycin Topical (Suzen-NS Cream)?
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Neomycin Topical (Suzen-NS Cream), the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to Neomycin Topical (Suzen-NS Cream) or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Damage to hearing, sense of balance, and kidneys is more likely to occur in premature infants and neonates, who are more sensitive than adults to the effects of Neomycin Topical (Suzen-NS Cream).
Geriatric
Serious side effects, such as damage to hearing, sense of balance, and kidneys may occur in elderly patients, who are usually more sensitive than younger adults to the effects of Neomycin Topical (Suzen-NS Cream).
Pregnancy
Pregnancy Category
Explanation
All Trimesters
D
Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking Neomycin Topical (Suzen-NS Cream), it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using Neomycin Topical (Suzen-NS Cream) with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Amifampridine
Using Neomycin Topical (Suzen-NS Cream) with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Alcuronium
Atracurium
Cidofovir
Cisatracurium
Colistimethate Sodium
Decamethonium
Doxacurium
Ethacrynic Acid
Fazadinium
Foscarnet
Furosemide
Gallamine
Hexafluorenium
Metocurine
Mivacurium
Pancuronium
Pipecuronium
Rapacuronium
Rocuronium
Sorafenib
Tacrolimus
Tubocurarine
Vecuronium
Using Neomycin Topical (Suzen-NS Cream) with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Bumetanide
Digoxin
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of Neomycin Topical (Suzen-NS Cream). Make sure you tell your doctor if you have any other medical problems, especially:
Blockage of the bowel
Eighth-cranial-nerve disease (loss of hearing and/or balance)—Oral Neomycin Topical (Suzen-NS Cream) may increase the chance of hearing loss and/or balance problems
Kidney disease—Patients with kidney disease may have an increased chance of side effects
Myasthenia gravis or
Parkinson's disease—Patients with myasthenia gravis or Parkinson's disease may have an increased chance of developing muscular weakness
Ulcers of the bowel—Patients with ulcers of the bowel may have an increased chance of side effects since more Neomycin Topical (Suzen-NS Cream) may be absorbed by the body
Neomycin Topical (Suzen-NS Cream) precautions
Certain people who are very sick or very old or who are sensitive show an exacerbation of side effect of the drug which can turn dangerous at times. So, it is very important to remember the precautions while taking the medicine. Pregnancy and Breastfeeding are also special categories wherein extra care or precaution is needed when taking a drug. Few patients may have a hypersensitivity reaction to few medications, and that can be life-threatening rarely. Penicillin hypersensitivity is one example. Diarrhea, rashes are few other symptoms which need a watch. A patient with other co-existing diseases like liver disease, heart disease, kidney disease should take special precautions.
General
Prescribing Neomycin Topical (Suzen-NS Cream) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
As with other antibiotics, use of oral Neomycin Topical (Suzen-NS Cream) may result in overgrowth of nonsusceptible organisms, particularly fungi. If this occurs, appropriate therapy should be instituted.
Neomycin Topical (Suzen-NS Cream) is quickly and almost totally absorbed from body surfaces (except the urinary bladder) after local irrigation and when applied topically in association with surgical procedures. Delayed-onset irreversible deafness, renal failure and death due to neuromuscular blockade (regardless of the status of renal function) have been reported following irrigation of both small and large surgical fields with minute quantities of Neomycin Topical (Suzen-NS Cream).
Cross-allergenicity among aminoglycosides has been demonstrated.
Aminoglycosides should be used with caution in patients with muscular disorders such as myasthenia gravis or parkinsonism since these drugs may aggravate muscle weakness because of their potential curare-like effect on the neuromuscular junction.
Small amounts of orally administered Neomycin Topical (Suzen-NS Cream) are absorbed through intact intestinal mucosa.
There have been many reports in the literature of nephrotoxicity and/or ototoxicity with oral use of Neomycin Topical (Suzen-NS Cream). If renal insufficiency develops during oral therapy, consideration should be given to reducing the drug dosage or discontinuing therapy.
An oral Neomycin Topical (Suzen-NS Cream) dose of 12 grams per day produces a malabsorption syndrome for a variety of substances, including fat, nitrogen, cholesterol, carotene, glucose, xylose, lactose, sodium, calcium, cyanocobalamin and iron.
Orally administered Neomycin Topical (Suzen-NS Cream) increases fecal bile acid excretion and reduces intestinal lactase activity.
Information for The Patient
Patients should be counseled that antibacterial drugs including Neomycin Topical (Suzen-NS Cream) tablets should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Neomycin Topical (Suzen-NS Cream) tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Neomycin Topical (Suzen-NS Cream) tablets or other antibacterial drugs in the future.
Before administering the drug, patients or members of their families should be informed of possible toxic effects on the eighth nerve. The possibility of acute toxicity increases in premature infants and neonates.
Laboratory Tests
Patients with renal insufficiency may develop toxic Neomycin Topical (Suzen-NS Cream) blood levels unless doses are properly regulated. If renal insufficiency develops during treatment, the dosage should be reduced or the antibiotic discontinued. To avoid nephrotoxicity and eighth nerve damage associated with high doses and prolonged treatment, the following should be performed prior to and periodically during therapy: urinalysis for increased excretion of protein, decreased specific gravity, casts and cells; renal function tests such as serum creatinine, BUN or creatinine clearance; tests of the vestibulocochlearis nerve (eighth cranial nerve) function.
Serial, vestibular and audiometric tests should be performed (especially in high-risk patients). Since elderly patients may have reduced renal function which may not be evident in the results of routine screening tests such as BUN or serum creatinine, a creatinine clearance determination may be more useful.
Drug Interactions
Caution should be taken in concurrent or serial use of other neurotoxic and/or nephrotoxic drugs because of possible enhancement of the nephrotoxicity and/or ototoxicity of Neomycin Topical (Suzen-NS Cream).
Caution should also be taken in concurrent or serial use of other aminoglycosides and polymyxins because they may enhance Neomycin Topical (Suzen-NS Cream)’s nephrotoxicity and/or ototoxicity and potentiate Neomycin Topical (Suzen-NS Cream)’s neuromuscular blocking effects.
Oral Neomycin Topical (Suzen-NS Cream) inhibits the gastrointestinal absorption of penicillin V, oral vitamin B-12, methotrexate and 5-fluorouracil. The gastrointestinal absorption of digoxin also appears to be inhibited. Therefore, digoxin serum levels should be monitored.
Oral Neomycin Topical (Suzen-NS Cream) may enhance the effect of coumarin in anticoagulants by decreasing vitamin K availability.
Carcinogenesis, Mutagenesis, Impairment of Fertility
No long-term animal studies have been performed with Neomycin Topical (Suzen-NS Cream) to evaluate carcinogenic or mutagenic potential or impairment of fertility.
Pregnancy Category D
Nursing Mothers
It is not known whether Neomycin Topical (Suzen-NS Cream) is excreted in human milk, but it has been shown to be excreted in cow milk following a single intramuscular injection. Other aminoglycosides have been shown to be excreted in human milk. Because of the potential for serious adverse reactions from the aminoglycosides in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Pediatric Use
The safety and efficacy of oral Neomycin Topical (Suzen-NS Cream) in patients less than 18 years of age have not been established. If treatment of a patient less than 18 years of age is necessary, Neomycin Topical (Suzen-NS Cream) should be used with caution and the period of treatment should not exceed two weeks because of absorption from the gastrointestinal tract.
What happens if I miss a dose of Neomycin Topical (Suzen-NS Cream)?
When you miss a dose, you should take it as soon as you remember, but you should take care that it should be well spaced from the next dose. You should not take an extra dose at the time of the second dose as it will become a double dose. The double dose can give unwanted side effects, so be careful. In chronic conditions or when you have a serious health issue, if you miss a dose, you should inform your health care provider and ask his suggestion.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
References
DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
DailyMed. "BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
