Syzeron Uses

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How times a day do you take this medicine?

What is Syzeron?

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Guaifenesin and phenylephrine is a combination medicine used to treat stuffy nose and sinus congestion, and to reduce chest congestion caused by the common cold or flu.

Guaifenesin and phenylephrine may also be used for purposes not listed in this medication guide.

Syzeron indications

infoAn indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.
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paracetamol is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of paracetamol, chlorpheniramine, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, sneezing, and pain or fever caused by allergies or the common cold.

paracetamol, chlorpheniramine, and phenylephrine may also be used for other purposes not listed in this medication guide.

Uses of Syzeron in details

infoThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

This combination medication is used to temporarily treat cough and runny/stuffy nose (nasal congestion) caused by infections (such as the common cold), allergies (such as hay fever), and other breathing illnesses. This product is usually not used for ongoing cough from smoking or long-term breathing problems (such as chronic bronchitis, emphysema) unless directed by your doctor. Guaifenesin is an expectorant. It works by thinning and loosening mucus in the airways, clearing congestion, and making breathing easier. Phenylephrine is a decongestant (sympathomimetic). It reduces nasal congestion by narrowing the blood vessels in the nose.

If you are self-treating with this medication, it is important to read the package instructions carefully before you start using this product to be sure it is right for you.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

How to use Syzeron

Take this medication by mouth with or without food, as directed by your doctor. If you are self-treating, follow all directions on the product package. To prevent trouble sleeping, do not take this medication close to bedtime. If you are uncertain about any of the information, ask your doctor or pharmacist.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed.

Guaifenesin may have a bitter taste. Swallow capsules and tablets whole. Scored tablets may be split for lower doses. Chewable tablets may be swallowed whole or chewed.

Drink plenty of fluids while taking this medication. Fluids will help to break up mucus and clear congestion.

If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.

Tell your doctor if your condition is accompanied by fever, severe sore throat, rash, persistent headache, or if it persists, returns, or worsens after 7 days. These may be signs of a serious medical problem. Seek immediate medical attention if you think you may have a serious medical problem.

Syzeron description

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Syzeron Syzeron is an anti-histaminic drug which is mainly used for the control of vomiting due to motion sickness. Syzeron Syzeron was first synthesized by Janssen Pharmaceutica in 1955t acts by interfering with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. The disparity of signal processing between inner ear motion receptors and the visual senses is abolished, so that the confusion of brain whether the individual is moving or standing is reduced. Vomiting in motion sickness is actually a physiological compensatory mechanism of the brain to keep the individual from moving so that it can adjust to the signal perceptioninnarizine Syzeron could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. It is also effectively combined with other nootropics, primarily piracetam; in such combination each drug potentiate the other in boosting brain oxygen supply.

Syzeron dosage

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Adults and Children >12 years: Peripheral Circulatory Disorders: Two to three 25-mg tab 3 times daily.

Disorders of Balance: One 25-mg tab 3 times daily.

The maximum recommended dosage should not exceed 225 mg (9 tabs) daily, if necessary the dosage may be divided over 2 or 3 intakes/day. As the effect of Syzeron on vertigo is dose dependent, the dosage should be increased progressively.

Motion Sickness: Adults: 25 mg may be taken 2 hrs before the start of the journey and 12.5-25 mg may be repeated every 8 hrs during the journey when necessary.

Children 8-12 years: 12.5 mg 3 times daily when necessary; 5-7 years: 6.25 mg 3 times daily when necessary.

As with other antihistamines, Syzeron may cause epigastric distress; taking it after meals may diminish gastric irritation.

Syzeron interactions

See also:
What other drugs will affect Syzeron?

Alcohol, CNS Depressants and Tricyclic Antidepressants: Concurrent use may potentiate the sedative effects of either of these medications or of Syzeron.

Diagnostic Interference: Because of its antihistamine effect, Syzeron may prevent otherwise positive reactions to dermal reactivity indicators if used up to 4 days prior to skin testing.

Syzeron side effects

See also:
What are the possible side effects of Syzeron?

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The most common antihistaminic side-effect of Syzeron is sedation which can vary from slight drowsiness to deep sleep, and including inability to concentrate, lassitude, dizziness, and inco-ordination. Sedative effects, when they occur, may diminish after a few days.

Other side-effects include gastro-intestinal disturbances such as nausea, vomiting, diarrhoea or constipation, anorexia or increased appetite and epigastric pain.

Somnolence and gastro-intestinal disturbances are usually transient and may often be prevented by achieving the optimum dosage gradually.

Syzeron may also produce antimuscarinic effects such as blurred vision, difficulty in micturition, dysuria, dryness of mouth and tightness of chest.

Central effects may include muscular weakness, headache and euphoria.

Weight gain, perspiration or allergic reactions may be observed. Cases of lichen planus and lupus-like symptoms and an isolated case of cholestatic jaundice have been reported.

In elderly people cases of aggravation or an appearance of extrapyramidal symptoms sometimes associated with depressive feelings have been described during prolonged therapy. The treatment should be discontinued in such cases.

Interactions:

Syzeron may enhance the sedative effect of central nervous system depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, tricyclic antidepressants, sedatives and tranquillisers.

The side-effects of anticholinergic substances such as atropine and tricyclic antidepressants may be enhanced by the concomitan administration of antihistamines.

Monoamine-oxidase inhibitors may enhance the antimuscarinic effects of antihistamines.

Syzeron contraindications

See also:
What is the most important information I should know about Syzeron?

In patients with known hypersensitivity to Syzeron.

The safety of Syzeron tablets in pregnant and lactating women has not been established.

Parkinson’s disease.

Active ingredient matches for Syzeron:

Cinnarizine in India.


Unit description / dosage (Manufacturer)Price, USD
Syzeron 25mg TAB / 100$ 3.08
Syzeron 75mg TAB / 100$ 6.86
25 mg x 100's$ 3.08
75 mg x 100's$ 6.86
Syzeron 25 mg Tablet$ 0.03
Syzeron 75 mg Tablet$ 0.07
SYZERON 25 MG TABLET 1 strip / 10 tablets each (Psycormedies)$ 0.31
SYZERON 75 MG TABLET 1 strip / 10 tablets each (Psycormedies)$ 0.69
SYZERON tab 25 mg x 10's (Psycorem)$ 0.31
SYZERON tab 75 mg x 10's (Psycorem)$ 0.69
Syzeron 25mg Tablet (Psycormedies)$ 0.03
Syzeron 75mg Tablet (Psycormedies)$ 0.07

List of Syzeron substitutes (brand and generic names):

Taveron 25 mg Tablet (Chemo Biological)$ 0.02
Taveron Forte 75 mg Tablet (Chemo Biological)$ 0.06
Tinimin 25 mg Tablet (Albatross Pharma)$ 0.02
TINIMIN FORTE TABLET 1 strip / 10 tablets each (Albatross Pharma)$ 2.72
Tinimin NA Tablet (Albatross Pharma)$ 0.27
6 mg x 10's (Biochemix Healthcare Pvt Ltd)$ 2.34
Tinver 6 mg Tablet (Biochemix Healthcare Pvt Ltd)$ 0.23
Tinver 6mg TAB / 1 (Biochemix Healthcare Pvt Ltd)$ 2.34
TINVER tab 6 mg x 10's (Biochemix Healthcare Pvt Ltd)$ 2.34
ULIVERT tab 25 mg x 10's (Unique Life Sciences)
ULIVERT tab 50 mg x 10's (Unique Life Sciences)
Tablets; Oral; Cinnarizine 25 mg (Ccm)
Uphageron 25 mg x 100 x 10's (Ccm)
Urizine 25 mg x 50 x 10's (Unison)
Tablets; Oral; Cinnarizine 25 mg (Unison)
Urizine tab 25 mg 50 x 10's (Unison)
V Gon 75 mg Tablet (Aarpik Pharmaceuticals Pvt. Ltd.)$ 0.07
V Gon 25 mg Tablet (Aarpik Pharmaceuticals Pvt. Ltd.)$ 0.03
V GON 25MG TABLET 1 strip / 10 tablets each (Aarpik Pharmaceuticals Pvt. Ltd.)$ 0.27
V Gon 25mg Tablet (Aarpik Pharmaceuticals Pvt. Ltd.)$ 0.03
V-Gon 25mg TAB / 10 (Aarpik)$ 0.27
V-Gon 75mg TAB / 10 (Aarpik)$ 0.67
25 mg x 10's (Aarpik)$ 0.27
75 mg x 10's (Aarpik)$ 0.67
V-GON tab 25 mg x 10's (Aarpik)$ 0.27
V-GON tab 75 mg x 10's (Aarpik)$ 0.67
Vasonic 25 mg Tablet (Tunic Healthcare)$ 0.02
VERIFIX 25MG TABLET 1 strip / 10 tablets each (Canixa Life Sciences Pvt)$ 0.40
Vernarin 25 mg x 500's (Nakornpatana)
Verticin 25mg TAB / 10 (Acto Pharmaceuticals Laboratories)$ 0.47
Verticin 75mg TAB / 10 (Acto Pharmaceuticals Laboratories)$ 0.94
25 mg x 10's (Acto Pharmaceuticals Laboratories)$ 0.47
75 mg x 10's (Acto Pharmaceuticals Laboratories)$ 0.94
Verticin 75 mg Tablet (Acto Pharmaceuticals Laboratories)$ 0.09
Verticin 25 mg Tablet (Acto Pharmaceuticals Laboratories)$ 0.05

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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